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Ep 11559m · 23 July 2026 · Learn

Peptide Q&A #51 – HGH vs IGF-1 LR3, Wolverine for Dogs, GHRH & GHRP Explained & Low Libido on TRT

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Research use only

Any compounds discussed may be intended for research purposes only. Nothing here is a protocol to follow — amounts, timing and cycle lengths are reported as the named speaker described them.

In this episode

14 chapters. Timecodes play from that moment.

Episode notes

Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover whether HGH and IGF-1 LR3 can be stacked safely, why libido stays low even on TRT, Wolverine protocols for a 69-year-old with nine surgeries, why peptides don't show on drug tests, and how to dose BPC and TB-500 for a 125-pound dog.

Chapters

We cover:

• HGH + IGF-1 LR3 Together Safe or Not?: Why doubling up amplifies muscle building but also amplifies insulin sensitivity risk and who should and shouldn't do it

• Why GHRH and GHRP Work Better Together: How Sermorelin and Ipamorelin amplify each other's pulses and why Tesamorelin plus low-dose Ipa is the best combo for women prone to water retention

• 69-Year-Old LEO with Nine Surgeries: Why high-dose Wolverine is safe, why two migs of each daily post-surgery is the target, and why injecting close to the site matters

• Diverticulosis & Ulcerative Colitis Protocol: Why oral BPC and KPV are the foundation and why most medications are probably making the gut worse

• High LDL on Retatrutide in Women: Why rapid fat loss temporarily raises LDL, why it's not alarming at 106, and why the scale is the wrong metric to chase

• Low Libido at 44 on TRT: Why free testosterone matters more than total, why 100 migs may be too low, and why diet, sleep, cortisol and estrogen all outrank more testosterone

• Do Peptides Show Up on Drug Tests: Why no standard employment test screens for peptides and why the economics of testing make it nearly impossible

• Gastric Sleeve Patient Stalled at 145 Pounds: Why eating more protein not fewer calories is the fix and why adding Tesamorelin and Ipamorelin raises your BMR over time

• Switching Mom from Wegovy to Retatrutide: Why going pound for pound on dosage is the simplest approach and why she'll feel hunger again and that's okay

• Wolverine Protocol for a Saint Bernard Post Spinal Surgery: Why a human-sized dose is appropriate for a 125-pound dog, what the beagle studies show, and how to inject intramuscular

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Sources cited
0
Runtime
58:55
Chapters
14
Category
Learn

Compounds discussed

Peptide A–Z →
TB-500SermorelinIpamorelinBPC-157TesamorelinRetatrutide

From the transcript

Full transcript, searchable, every episode.

Read the full transcript →

Welcome back to the pep time of the week podcast. I'm your host JD Denham across the way like always,

Speaker 0 · 0:09

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