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Ep 1251h 32m · 27 August 2026 · Learn

Peptide Q&A #56 – SS-31 Deep Dive, Fertility on TRT & Building Muscle

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Ep 125
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Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover why SS-31 has been a game changer for JD, how to properly sequence the mitochondrial stack, NAD reactions and replacements, when to come off R, building muscle at 12% body fat, fertility protocols while on TRT, and whether you really need to plan your protocols a year in advance.

Chapters:

00:00 – Intro & Personal Health Updates

03:06 – SS-31 & Finding the Right Protocol

06:04 – Disneyland Trip & Kids' Sports Talk

13:48 – Warrior Makers Coaching Program Launch

18:37 – School Platform Updates & Podcast Feedback

21:58 – Q&A: Sleep, Hormones & Energy for a Busy Mum

34:15 – Q&A: Major Weight Loss & a Bad NAD Reaction

39:07 – Q&A: Peptide Storage & Condensation

41:50 – Q&A: SS-31, MOTS-C & NAD Sequencing

49:31 – Q&A: Coming Off Retatrutide's Maintenance Dose

55:22 – Q&A: TRT & Fertility Protocols

1:08:14 – Q&A: Gut Health Flare-Up & Peptide Pause

1:14:53 – Q&A: Runner Wanting Muscle Over Fat Loss

1:21:14 – Q&A: Building a Smart Annual Peptide Plan

1:29:13 – Outro & Coaching Call Details

We cover:

• Why JD Is Feeling the Best He Has in Years: Why higher-dose SS-31 gets the credit, why less compounds often means feeling better, and why starting with two compounds and adding slowly is the smarter approach

• NAD Allergy What to Do Instead: Why reactions to NAD may come from the compound itself not just contamination, why SS-31 at five-plus megs is the closest alternative, and why blood work and hormone optimization should come first at 35

• Peptide Storage and Condensation on Vials: Why condensation on the outside of a vial does not mean moisture got inside, and why a dedicated mini fridge beats any canister solution

• Mitochondrial Stack SS-31, MOTS-C and NAD Sequenced Properly: Why SS-31 plugs the holes before MOTS-C revs the engine, why quarterly month-long SS-31 cycles make sense, and why NAD can run anytime regardless

• 42-Year-Old Australian Female Should You Come Off R: Why she probably doesn't need it at all, why 5-Amino-1-MQ and SLU-PP-332 are the right replacements, and why discipline is a better long-term tool than any GLP

• Fertility Protocol at 33 While Trying for a Baby: Why TRT doesn't have to stop, why HCG and Kisspeptin together improve fertility odds, and why Enclomiphene is the smarter choice over standard Clomid

• Building Muscle at 12% Body Fat and Running 60-70 Miles a Week: Why all that running is burning off the muscle she's trying to build, why cutting back to HIIT and lifting heavy is the real answer, and why low-dose testosterone may matter more than any IGF-1

• Total T of 420 at 43 Is It Time for TRT: Why 420 with low energy is answer enough, why TRT will change his life, and why planning protocols a full year out is overrated for most people

• How to Build a Smart Annual Protocol Without Overcomplicating It: Why JD and Will plan four months at a time, why trying too many compounds at once tells you nothing, and why the gateway compounds R and BPC are always the right starting point

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Will's Instagram: https://www.instagram.com/williamthaas/

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Research use only

Any compounds discussed may be intended for research purposes only. Nothing here is a protocol to follow — amounts, timing and cycle lengths are reported as the named speaker described them.

We are not doctors. Use at your own risk.

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