Any compounds discussed may be intended for research purposes only. Nothing here is a protocol to follow — amounts, timing and cycle lengths are reported as the named speaker described them.
In this episode
11 chapters. Timecodes play from that moment.
Episode notes
Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover the right order for mitochondrial peptides, why sleep and cortisol matter more than any compound, switching from Tirzepatide to Retatrutide, bone density protocols, and what body recomposition actually looks like on the scale.
Chapters:
We cover:
• Switching From Tirzepatide to Retatrutide: Why at low doses you can swap directly and why more frequent dosing beats once a week
• Tesofensine for Anxiety & GLP Transition: Why it's the best next step coming off GLPs and what to watch for if anxiety is already a factor
• Mitochondrial Stack Order: Why SS-31 comes before MOTS-C every time, what FOXO4 does, and why lifestyle fundamentals come before any peptide
• HGH Debate — Worthless or Essential?: Why HGH is a long play, why secretagogues lose effectiveness as the pituitary ages, and why real HGH wins for men over 40
• Which HGH Is Actually Best: Why Somatropin, Serostim and Genotropin are all identical and what the different kit sizes actually mean
• Firefighter Sleep & Cortisol Protocol: Why cortisol takes the top seat over testosterone, the supplement stack that fixed JD's sleep, and why sunlight and grounding still matter
• Tesamorelin + Retatrutide for Visceral Fat: Dosing both together, why gaining weight but losing inches is actually the goal, and what body recomposition really looks like
• Perimenopause Protocol Simplified: Why the Klow blend, TA-1, NAD, SS-31 and creatine cover most bases with minimal injections
• Bone Density & Osteopenia at 59: Why HGH plus resistance training beats calcium advice, and what's emerging in bone-specific peptide research
• Insulin Resistance, Anxiety & Tirzepatide in a 30-Year-Old: Why blood sugar normalizing feels like hypoglycemia, why switching to Retatrutide helps, and why NAD can worsen anxiety in some people
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Compounds discussed
From the transcript
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