Ep 122 · 1:08:32
Full transcript
Machine transcribed. Not yet read against the audio.
Research use only
Any compounds discussed may be intended for research purposes only. Nothing here is a protocol to follow — amounts, timing and cycle lengths are reported as the named speaker described them.
We are not doctors. Use at your own risk.
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1:06Speaker 2Welcome back to the Pepatide of the Week podcast. I'm your host JD Denham. Across the way to my left
1:15Speaker 2a man that has been on our show numerous times. You know him as Doctor. Scott. I know him as
1:22Speaker 2Scotty because I've known him a long time. Doctor. Scott Cawley, he practices functional
1:39Speaker 2before we recorded and I wish we were kind of recording because we were talking about just
1:44Speaker 2the difference in food from, you know, Will just got back from Italy and we were talking, which everybody's heard these conversations, people that go to Italy and the food and
1:54Speaker 2what Will was saying, just put words out of take words out of his mouth was it was bland, but it was great. And he didn't feel heavy.
2:00Speaker 2And we were thinking like, that's just how food's supposed to taste, not full of sugar and sea oils and like stuff to make you get addicted. You know what I mean?
2:17Speaker 0now that I've been back, like not happy eating this, anything that's not just fresh food.
2:24Speaker 0I can feel it directly. I've heard that story over and over again too. Just to let you know. Probably, I mean, I probably lost, I probably probably could lost like 8 pounds. You do look thinner, bro.
2:44Speaker 0and swimming. But you know, on a vacation, I always try to like not really work out and let my whole injuries heal because there's always, if you lift enough every day,
2:57Speaker 0in heat and eat really good. I guess you stay in Positano and you're walking straight up mountains all the time. But
3:05Speaker 0I feel way better until I order little Caesar's pizza with my kid and have a pie piece of pizza and it like ruined my day the next day. So
3:30Speaker 2Because this is all we've known, you know, I mean, maybe some of us, cause I'm almost 50. So maybe some of us got some of the old school stuff, but like,
3:38Speaker 2that's why we, this is all, this is what we've known. But like, if like you have Italians come to America, they're like, what is this shit? You know what mean? Like, what is this? What is this taste? What is it? You know, they're not in shock.
3:49Speaker 3Yeah. It's just sugar. They taste the sugar. There's sugar and everything. Like, people don't even realize there's, like, sugar and salads.
4:05Speaker 3go to Australia. He goes, There's real food there. He goes, This food here tastes like, even he goes, the best food here tastes like the worst we got over there. Wow. You know, they got good. That sucks. They got great agricultural farming in Australia too, Italy. Like I said, Costa Rica was great food. You know, there was, it just, different. Yeah. I mean, we've all been places to where,
4:28Speaker 2he just got back from Costa Rica. Same thing if you go to Hawaii, I mean, you get the pokey that they catch that day.
4:35Speaker 2I mean, there is a difference about how amazing that it and the cool thing about Hawaii is
4:41Speaker 2a lot of times, Alyssa and I will just go to the grocery store, then they have like 15 different options caught that day. Yeah. And we're like, we're tired, so we just go to
4:55Speaker 3our grocery store that it's been just not doing well. And this is wild caught fish. That's a big difference. Farm drink. You got a sushi bar here. You you got to ask for the wild caught selections because so much of it is, you know, farmed race selection, which isn't always the best, you know? Yeah.
5:14Speaker 2you know, we're all into the same stuff. You know, I've been friends with both these guys for a very long time. I've been with Scott before
5:34Speaker 2Now there's a lot of autoimmune issues and things like that these days that like maybe even the nutrition can fight against some of the bacterias and some of the stuff going on in the gut. I mean, you're,
5:54Speaker 2Scott's been on the show quite a bit and we've talked about a lot of different things, but he reached out to me the other day and said, Hey, I'd like to kind of come on and
6:03Speaker 2talk about some of the stuff that I've seen in blood work because he runs deep, deep, deep panels. I've shared about him running my deep panel then which turned into a stool test and all that stuff,
6:18Speaker 2You see a lot of men that are running gear, which if you don't know what that means, it means steroids,
6:27Speaker 2For, I'm gonna probably burst somebody's bubble right now or people's bubble when I say this. So if you don't want your bubble to be bursts, plug your ears.
6:41Speaker 2And I know that, I remember I told my wife that back in the day, she's like, no. You're gonna get some crap from that. Yeah. And it's the truth. Listen, listen, I'm an honest guy. There's a 1 person truth adage. Yeah,
6:53Speaker 2right. I'm not saying it's not like ever, like it's not 100% of the time, but let's just call it what it is because
7:05Speaker 2You're here today to talk about some of the things that negatives that you're seeing on the blood work. And this is going to be a good conversation because you don't usually reach out to me and say, Hey man, I think I should talk about this. So that's odd for you. So let's kind of dig into it. What are some of the things
7:19Speaker 0that you're seeing that are of concern? Hey, can I add 1 interject real quick? The bursting of the bubble is also folks like you're probably gonna talk about people doing TRT.
7:43Speaker 2amount. Yeah. When we say gear, running gear, it's generally running a steroid cycle. Like, TRT, if you're running it properly,
7:51Speaker 2is generally about 1 50 to 1 80 megs a week. That's not exact, so don't like, don't normally lose their mind over that.
7:59Speaker 2When you start going to higher doses, even if you're running 400 testosterone, like people will be like, I'm running TRT. No, you're not. Steroid
8:13Speaker 2Tran, Mastro, Cream of All, and like we could go on and on. They're actually running steroid cycles for a specific reason to get big and ripped and buff, whatever their objective is. Including high dose of testosterone. High dose of- I want to differentiate
8:27Speaker 3the TRT versus the ear side. And that's kind of what I was going say anyways was TRT, I think, is extremely important.
8:38Speaker 3You Right? Get them to the balance. It's not about going supra physiologic where we would go over. And that's where we start going into the gear side. So TRT is
8:47Speaker 3not what I'm really talking about, although I think it's extremely important for people who are on TRT, not just men, right? Women too now, a lot of women going on it. Yeah. Is to just to make sure, you know, because all
9:19Speaker 3Making sure you're getting that all in there and doing it responsibly, I think is not really who I'm talking about today. Because
9:25Speaker 3this platform is, I get a lot of guys who are coming at me who are on the gear side. I always like you know, we talk about gear. I always like to compare it to like a football field. Know, you got, you got testosterone as the quarterback. Yeah. Right? You got, you got the running backs, right? That would be like Primo Bollin and maybe Mastron. You got the receivers. We got, you know, we got Winstrolin and Anovar. You got you got, oh, the tight end will be Tremblon. You got center, a deck of Dura Bowen. Right? And then and then who's the kicker? Right? Who I don't know. Who would the kicker be? This is the kicker without Anovar. Anovar is the kicker of So, Anovar's the kicker, bro.
10:01Speaker 3You know, and then you're going to, you know, plays, you're going to use different players. So, guys are coming What's the objective? How are we going to get to the end zone? Exactly. And different
10:15Speaker 3a proponent of anabolic steroid use. I want to put that out there. You see the blood work. It's damaging.
10:21Speaker 3A lot of it's reversible and some of it is not reversible. There's irreversible damage to do an anabolic steroid. I'm going to put that out there. We're be juicy.
10:33Speaker 3they're running labs sometimes right smack in the middle of their cycles and sometimes they're on the off cycle.
10:48Speaker 3So I'm seeing here is there's a big difference whether you're going to run off cycle or on cycle 1st. So I always tell the patient that you're on, be ready. Going to see
10:57Speaker 3an ugly report. I can almost guarantee you're going to see an ugly report. When you're off, get to see like, okay,
11:15Speaker 3long term, maybe short term that can be reversed. What I like to do is there is a way to do it better. That's kind of what if you're gonna make the decision to do that and to go down that path, the anabolic steroid path,
11:26Speaker 3there's always gonna be a better way to do it. Yeah, it costs money because you wanna run labs, you want to take supplementation. There's peptides now that we're
11:34Speaker 3we'll get into about peptides that help with the anti inflammatory effect of what's, know, steroids cause inflammation in the body.
11:41Speaker 3So, you know, when I see a lab report come in, let's just start with the guys who are in
11:57Speaker 3kidney, liver. Those ones seem to be affected a lot. And we gotta remember you guys, cardiovascular
12:07Speaker 31 taker outer. I think it's heart attack is number 1 and stroke is still number 2. And I don't know how long that's been, but it hasn't changed.
12:22Speaker 3I think that it's really important. I really like to go deep diving with, especially with the guys on anabolics into the cardiovascular
12:32Speaker 3Outside of people who are not doing anabolics, if you're 40 and above, I still like to go kind of deeper into the cardiovascular workup. And when I say deeper, I mean going past total cholesterol, HDL, and LDL C. That's kind of what you get from an insurance panel and really kind of looking deep into these panels because
13:05Speaker 3may not be optimized as far as how it should be running. So when you have a hypothyroid response,
13:17Speaker 3Those are markers that we want to run too. Let me I think what I should probably do is go through a list of what I run.
13:24Speaker 3The things that I would say for you guys who are doing these cycles, who really have no idea where they're at. I get a lot of guys who say, Hey, I've been running for a year or I've been running for 20 years, 30 And I just want to know, like, what has this been doing to my body? You know what I mean? And I think it's smart because
13:43Speaker 3want to There's things You don't want to die. Well, yeah, that and there's ways you can There's things that you can take. There's things that you can do. There's lifestyle changes you can make while you're living that lifestyle to
13:53Speaker 3help kind of manage, I guess. Sometimes even reverse eventually, you you go off cycle, you can reverse some of these things so that when you're going to go back on, you know that you've kind of come back down on some of this stuff. That's what it's called cycle. You go on and off. You don't stay on. Yeah. And again, I'm not here to ever tell anybody what to do on that. That's
14:15Speaker 3don't dictate how long to see steroids, what steroids to take. It's just not me. TRT, different story. TRT is a whole different ballgame. But I think what I like to start with is everything that
14:27Speaker 3workup. We want to look at obviously blood sugar. Blood sugar is going to be important. You want to look at fasting glucose, you want look at your hemoglobin A1C and fasting insulin,
14:51Speaker 3but they got an insulin that's through the roof or they got an LP IR score that's elevated, you know, that goes through 0 to 100%.
15:06Speaker 3get high insulin and then you got some, you know, what else elevates when we do, you know, testosterone is estrogen.
15:14Speaker 3So you get estrogen and insulin running together. That's kind of a disaster. So I always like to look Why though? Let's talk about that. I'm curious why.
15:29Speaker 3side together. They really fuel it hard. That's why insulin is such a big marker when you want to look at cardiovascular, it is looking at insulin. You want to get that insulin down. And the great news is Retatrutide,
15:41Speaker 3do you know the GLPs are really making a big difference in bringing down the insulin fast?
15:48Speaker 0Can I interject? So based on that, this is what I was going to ask. So what we know is, so if you do Reta, right, the GLP-one
16:07Speaker 3but that's bad. The mechanism behind the GLP is that it actually brings, I mean, it was produced. They were,
16:17Speaker 3then we're starting to see all the other good effects on this. Right? So, you know, you do a GLP and we're seeing the triglyceride come down, which is huge too. We didn't even talk about that. Triglycerides is another big marker. But you're seeing the insulin come down, the HbA-1c come down and the triglyceride come down. So I'm just saying, I'm not just trying to promote, you know, Retta here. Just saying that like a lot of people and are on
16:38Speaker 3it's I'm seeing good blood sugar patterns. Even the guys who are on the anabolics, it's great to see that those
16:45Speaker 3levels are down. It's when I see that the insulin is high when they're running really high gear,
16:51Speaker 3that's a red flag right away. I'll kind of stop and say, we need to start working on this insulin. How are you going to do that? How do you do that? A
17:02Speaker 3There's berberine, there's natural products that help to bring down. I use glycine, I use berberine. They're products that will kind of bring down high
17:10Speaker 3just making sure that you're doing some things like with supplementation is another part of this talk. What supplements can we take to combat some of the things that we're gonna see that are elevated? Do you feel like when you see these guys coming in, and this is like a very wide question, so like, do your best with it. So do
17:31Speaker 2educated to the degree on knowing some of those things that they need to do to kinda like liver like, you know, running like liver clans and stuff like that? Or do you just see they are just kind of
17:45Speaker 3There's some that know what they're doing because they have a computer in their pocket. Maybe 20%.
17:49Speaker 3Know what I mean? Like do some research. Mean, it's good to hear that there are some guys who are taking care of themselves while they're doing it. A lot of
18:01Speaker 3that's the ones that, you know, were of concern of me is to see like their lifestyle along with, you know,
18:16Speaker 0Especially over 40. Oh man. I mean, that's where we hear some of the horror stories of these bodybuilders dying
18:21Speaker 0is the guys who have been chronically abusing steroids, but also doing a whole bunch of cocaine and drinking a lot blood. Those are the people who end up
18:35Speaker 3you know, and I've seen that, you know, I'll see like, you know, on the questionnaire,
18:38Speaker 3I'll see, yeah, you know, they're on antibiotics and how many drinks per week? 5 to 7 drinks per week. That's
18:46Speaker 3ain't gonna look very pretty. I just, I warned them, this is not gonna look good. I'm just letting you know. So be prepared. I'm sure they know that. But let's continue down that list. We got the insulin. You want to look at kidney obviously, right? Because what anabolic steroids do is they obviously can increase blood pressure. So we want to look at kidney health. We want to look at the GFR. We want to look at creatinine level. We want to look at a cystatin C level. These are markers to kind of see the
19:17Speaker 3does hurt the kidneys. That's just 1 thing. And that's 1 of the things that's a little harder when I talk about irreversible damage.
19:34Speaker 3And that is the main marker for kidneys. How well are those kidneys functioning? That's how we gauge kidney failure, right?
19:41Speaker 3Sometimes you'll see other things that can fuel that to look bad though, too. Dehydration can
19:54Speaker 3want to look at kidney health. That's going to be really important, right? Because we know that elevated blood pressure is going to hurt the kidneys.
20:18Speaker 3I think that the good news is we're, you get in the mess, we're finding more ways to get out of the mess now that we really didn't have 10 years ago. And
20:28Speaker 3then I'll just keep going down the list. We got uric acid. People forget about uric acid. That is an inflammatory
20:43Speaker 3easy. That's because of usually poor diet. That's usually because of over excessive. You'll see that with the drinkers, the IPA guys who like the IPA beers. That causes gout. We've heard the term gout. Extremely painful. It's extremely inflammatory. It's not good cardiovascular
21:03Speaker 3ALT, and GGT and see how is the liver functioning, right? Obviously, that's a given. How do you and again, when you are on, you're going to see the AST and ALT go up. It's almost inevitable to see that, you know, when you're doing anabolics,
21:31Speaker 3is easy with the liver. You can kind of reverse that damage. You could bring those AST and ALTs down, especially when they go off cycle and they do some detoxification,
21:44Speaker 326. I like that range. When they're on antibiotics, you're seeing things up in the forties, fifties, sixties, seventies, eighties sometimes. Right? So we know that that's a sign that the liver is being stressed.
22:01Speaker 3total iron, because sometimes being on anabolic will drive up iron levels. And iron is a interesting It's a nutrient we all need. We need iron.
22:15Speaker 3right? Because you're not gonna have good red blood cells. Red blood cells, what's their purpose? They carry oxygen to those 30,000,000,000,000 cells that make up our body and they carry nutrients to the cell so that that cell can make ATP.
22:29Speaker 3Energy, right? The mitochondria, right? It needs that. So too much iron though is very toxic to the body. It hurts the cardiovascular system. It hurts the heart, the liver, the brain. It's
22:43Speaker 3would say it's almost as toxic as mercury if it's too high. Right? So you wanna look at the ferritin, you wanna look at the total iron and what's called the percent saturation in total iron binding capacity. It's a 4 marker panel in there to kind of get an overall look at what's going on with the iron physiology.
23:06Speaker 3Sometimes you're always going to see sometimes a little bit of an elevation in the iron and sometimes you'll see other patterns also.
23:13Speaker 3Certain anabolics are interesting. They can do certain things with iron. Some of them will increase iron. Some of them will decrease iron. See both
23:20Speaker 3different patterns with different types of anabolic, which is kind of interesting. Like oils compared to
23:38Speaker 3I'm learning a lot through your platform because I'm getting to see all these guys on all these different anabolics and what they're using and how are these ones affecting
24:03Speaker 3HDL and LDL. And then you'll get some ratios in there. You get the ratios. So I think the most important marker of that is the triglyceride.
24:33Speaker 3Sometimes you'll see that measurement from med doctors. It's great, you know, cardiologists and things like that. But triglyceride pretty much almost directly fuels what's called the VLDL,
24:57Speaker 3And HDL is called the good guy. And he's not a bad guy. I was like, give the guy a break for God's sake. For 60 years, he's been beat down into the bad guy because
25:10Speaker 3there's a difference between we're talking about LDL C and LDL P. LDL C is elevated. They just want to throw you on a statin drug and not look at anything.
25:19Speaker 3The LDL is responsible for carrying cholesterol from the liver out to the tissues. That's why he's the bad guy.
25:34Speaker 3system, unhealthy lifestyle. Okay? So he's called the bad guy, but he's also the 1 that carries cholesterol
25:41Speaker 3Your hormones are made of cholesterol. The building Like, amino acids are the building blocks of proteins. Well, guess what the building blocks of your hormones are? Cholesterol,
25:50Speaker 3right? It also is responsible for the, you know, all the cells. You got 30,000,000,000,000 cells in your body, the membrane of the
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26:51Speaker 3The cell is partially made of cholesterol. So cholesterol is very important. Hell, yeah. It's not a villain. It's not a bad guy. You wanna have a good balance. The HDL is called the good guy because he's the trucks. Let's just compare the Let's compare the lipoprotein
27:05Speaker 3profiles to trucks that carry the cholesterol around the body. LDL moves it out. HDL moves it back to the liver. Right? So you wanna have a good balance. You wanna have a You don't wanna have like, even if you have like decent LDL
27:18Speaker 3and a very low HDL, that's a little off. You wanna try to get HDL up because you want a good ratio of moving in. Trucks, I always like to use a construction site. Big truck, dump trucks moving in, dump trucks moving out. The sand and the rocks and the rubble, that's the cholesterol. You're moving this stuff around the body, But
27:41Speaker 3very inflammatory at the vascular level, just like LDL, VLDL is very inflammatory also. There's also 1 called IDL, which is a very small portion of the particle.
28:04Speaker 3It's a fatty liver and we do not want a fatty liver. When you start seeing triglycerides go up, gonna pretty much start to say, That is gonna be a fatty liver. That can be a lot, cause a lot of problems.
28:14Speaker 3You know, the liver's got about 1000 functions and all those functions are going to go, you
28:18Speaker 3know, down. So liver, very important organ of the body as we know, right? Because it's got so many functions. Give us a breakdown
28:25Speaker 0highlight for everybody. Just some of the basic, like, what does the liver do for a person? Give us some of the biggest things, the biggest things that the liver does. Detoxification, vitamin
28:42Speaker 3bile flow to make sure, mean, the list goes on and on. There's just so much that the liver is responsible for helping
28:49Speaker 3with proteins, breaking down proteins so that you can make immune products and transports
29:16Speaker 3Yeah, again, we talked about triglycerides fueling that, and then we want to go into the thyroid, right? Thyroid kind of brushed up on that.
29:27Speaker 3Sometimes you get 2 or 3 markers. I think it's more important to look at it a little bit more. I do 10 markers.
29:35Speaker 3Hashimoto's is the autoimmune side of thyroid. Pretty prevalent in a lot of that in today's, in our country.
29:58Speaker 3that are causing What I'm doing on my Hashimoto patients is I go to the gut and I kind of do that 1st.
30:13Speaker 3that I see very common. One's called Klebsiella pneumoniae, the 1 Citrobacter Friendi. I see those elevated
30:26Speaker 3I'm not. If I'm going make this a little more interesting, I'm to put your audience to sleep.
30:34Speaker 3rebuilding the gut, the lining of the gut. Autoimmunity is easy because you've got leaky gut involved with dysbiosis,
30:41Speaker 3meaning the gut's off. That kind of fuels the autoimmune side. I know there's more to it, but I'm really seeing awesome. So I'm seeing the autoimmune markers just dive, you know, through gut health. Gluten,
30:53Speaker 3I hate to say this, but- You mean going dive like mean they're going down? Going down? Yeah, sometimes completely negative.
31:06Speaker 3people. Celiac number 1, right? Yeah, celiac disease, you gotta stay away from gluten. Number 2, I'd say, Watch out, man. You got those
31:18Speaker 3Italy, I don't think. In our country, for some reason, gluten really kind of starts to fuel, you know, can fuel the Hashimoto's. We're finding that's been We've been talking about that for 10 years now, and that's been happening and we still kind of believe that.
32:05Speaker 3dysfunction where it's not going to be optimal, but it's good to see. It's good to see because hypothyroidism
32:40Speaker 3You never used to see this come from a panel from an insurance doctor and I'm starting to see this now because
33:03Speaker 3Maybe a little bit, but really what you wanna do is you wanna make sure that homocysteine
33:29Speaker 3You can get tested for that. I don't normally run into that unless I see a really, really high homocysteine.
33:46Speaker 3Different things go down these different conveyor belts. You got the methylation pathway,
33:54Speaker 3the glutathione pathway, and there's what's called 2 amino acid pathways. And certain things have to get detoxified through 1 of those conveyor belts. Homocysteine gets methylated.
34:20Speaker 3So you gotta make sure you gotta look at the whole picture. This guy got kidney failure. You might see high homocysteine. Kidneys are good. He's got high homocysteine.
34:40Speaker 3it's a free radical. I don't know if you've ever heard that term before, but it actually goes through the bloodstream and it kind of tears up the inside of those smooth vessels.
35:12Speaker 3just people need to methylate. And methylation is simple. I use B vitamins. There's B6, B12, and methylfolate.
35:33Speaker 3Is it enough just to see that homocysteine down? Is that gonna save you from cardiovascular
35:37Speaker 3disease again? No, you gotta look at the whole picture. You gotta look at the whole workup. It's a good thing to have down low because you definitely don't want it high. And if you methylate, you methylate a lot people, we lack B vitamins.
35:51Speaker 3wise, we're not getting it. People who drink alcohol deplete B vitamins, stress depletes B vitamins, blood sugar issues deplete B vitamins. Cortisol probably. Cortisol issues. So yeah, I mean, we gotta look at the whole platform and the whole picture of what would be causing that. It is pretty typical and it's so cheap and so effective to just methylate.
36:12Speaker 3they come to me, they wanna go on TNT. I say, Hey, say, you're If going to do this, you got to methylate because the testosterone, even being on TRT, will elevate the homocysteine level to some degree. It's just a good rule of thumb to follow
36:25Speaker 2for health. So you're saying methylated, but you're saying taking B vitamins. Methylators
36:30Speaker 3are the B vitamins. Okay. B vitamins are the So you're saying that the way how you say that to them is you say take these B vitamins. Yeah. That's it. Okay. And there's other methylators, by the way. There's other things besides just the B vitamins. There's other methylated products. Some certain,
36:50Speaker 3to make sure that you're getting that homocysteine down. It's just dependent on the patient. I always start with 1, are you doing on this? Oh man, I'm feeling anxious, anxiety. Okay, we got to flip that out. Very rare, but it happens and it's happened to me in practice.
37:03Speaker 3But it's fine. We just, there's another route. We just go this route and I'll do this methylator. This one's fine. I don't feel that anxiety and anxiousness on Is,
37:10Speaker 0is, is rapid or either these people who are taking Reta and they're losing 50 pounds in 3 months,
37:37Speaker 0Okay. So I don't know. I guess everybody, could you explain some of the bad things that can happen to a person when you lose weight way too fast? Yeah, I think what happens is we got to watch out for the bile flow.
37:58Speaker 3That is 1 of the things about when patients come to you and they want to do Retta, I always want to ask them about their gallbladder history. Do you have a gallbladder 1st? Number 1. Number 2, do you have the symptoms of potential gallbladder issues? There's people who I, you know, and on labs, you can look at labs and see if there's gallbladder. You look at what's called alkaline phosphatase and a GGT.
38:21Speaker 3there's a good chance and they're having symptoms. They belch a lot, they're gassy, they might get pain, you know, under their right rib cage.
38:28Speaker 3High fat meals cause distress to them. Their poops float. They don't sink. That's a sign of, you know, poor
38:37Speaker 0right? The call- I thought that was a good thing. I thought it was good to have your poop float. No, it's not good. Oh. Yeah, you want it to sink.
38:50Speaker 3means there's lot of fat in there. Okay. So that's a potential that you're not digesting your fats very well, which what would that be from? That would be from usually gallbladder issues. Because the gallbladder is responsible for bile acids and
39:03Speaker 3enzymes that break down the fat so that you can absorb the essential fatty acids and the cholesterol and things like that. So, like
39:09Speaker 3you said, going back to your question, Will, about all that fat loss real quick, I've seen it on labs.
39:14Speaker 3I've seen the fat. I just lost 40 pounds. I run the labs and I see the lipoprotein. I see the profiles are really kind of up. Like, you'll see the cholesterols and you'll see that up because they are just Yeah. They're trying to get rid of all that out of their body and it's backing up. Yeah, yeah, yeah. They're losing their weight. That's a good question, Will, because I wouldn't even think to talk about that, but I've seen that and it's been like, wow, check Because this
39:38Speaker 3then and you can, you know, people have labs, you know, because they send me all their labs, right? And then I run mine. So
39:44Speaker 3it's like, Hey, you know, it's like, you get to see like, Wow, look what a difference is. This doesn't look good. But
40:05Speaker 3I mean, I see way more gonna good than bad. Someone's got gallbladder issues, let's fix that 1st before you go on Retta because that can be a problem. You got major gut issues, you're only pooping once a week, probably That would suck.
40:19Speaker 3There's people Especially if eat Hey, I got people, they haven't pooped in 2 weeks. That's great. That is really bad. It's a severe issue.
40:33Speaker 3No poop. Went away, went on vacation for 3 weeks, didn't poop the whole time. Oh my gosh.
41:00Speaker 0Blood testing. But like, I can't change it. Yeah, I know how you do that. Just force Anyway. Eventually they go.
41:06Speaker 3Eventually they go. And again, you want to look at not just stool, want to look at blood. Is there something that's fueling that also in the blood work that's going to give us ideas? Something's not right. So we
41:34Speaker 3It's a gauge. It's like ferritin. I talked about iron. Right? Ferritin is called an acute phase reactant. CRPA I believe CRPA is acute phase reactant also. Maybe I'm wrong on that. But it's kind of like gauges. When you're treating someone, you want to see those going in the right direction because you know that things are getting better. Because those are both signs of something is not right. Something's inflammatory in the body, whether it's cancer,
42:00Speaker 3inflammation, inflammation, which is the number 1 killer really in the country is inflammation because everything that falls under that is usually an inflammatory disease.
42:16Speaker 3fibrinogen is a protein that's made in the liver. That's another thing the liver does that makes fibrinogen. It's a clotting protein.
42:42Speaker 3I don't know if you've heard of nattokinase. Have you heard of Yeah. Great, man. It's a proteolytic enzyme that breaks down fibrinogen.
42:51Speaker 3NAD-0KIN is a great product for guys on anabolic steroids because usually I see an elevation in fibrinogen that scares me a little bit. So I say, if you're going to do this, get on the nano and stay on it even when you're even when you're off,
43:32Speaker 2because we're coming up and I wanna get into some questions and whatnot, what we'll do is we'll have you put a list so people can find it on some of our things.
43:40Speaker 2What are some of the biggest fears you're seeing? Like, you like, what are what are the markers that you have seen? I know you've touched on a little bit, but like guys that are running gear that have made you fearful and this is kind of a problem. What are they? Yeah, so the lipoprotein particles, haven't talked about LDL particles,
43:56Speaker 3We talked about LDL C, right? That's just basically looking at the amount of cholesterol that's moving out. But you want to look at the trucks. We measure the trucks called the particles.
44:05Speaker 3Okay? So you look at how many trucks you have. Are they large trucks or small trucks? Large trucks are good. Small trucks are bad. Small trucks are the ones that clog the arteries. I measure the small LDL particles.
44:20Speaker 3That's really bad news. You got high uric acid, high insulin, high blood sugar. You see how it just keeps on fueling and filling in. You got low thyroid, you're gonna have a low thyroid response.
44:35Speaker 3that's the 1 that kind of looks at all the arterial sclerotic particles that you can have. It's kind of like an overall look. So it's another gauge look.
44:50Speaker 3B is looking at the different ones, the IDL, the VLDL particle, the LDL particles, at kind of all of them. Okay? But there's another marker that's really important to you that I it's a little pricey to run.
45:46Speaker 3of stress to the heart, because of high blood pressure? It's a great marker to see, Have I damaged my heart? I've been brought especially the guys who've been running it for 20, 30 years. Plus probably like high doses of HGH. Like we talk about HGH is a good thing, but like when you're running high doses, like everything grows. You
46:07Speaker 3So it's a good 1. It's a good 1 to check, especially the guys who've been in the game for a while.
46:11Speaker 3It's a good 1 for people too who just have high blood pressure. It doesn't have be on anabolic steroids. It's a great marker to run-in. The cardiologists run these. Cardiologists run it. Not all these, though. You're not going to see these- They won't run. You've been running to get all these. If you go to a cardiologist anytime, I've been lying on all exterior for 30 years.
46:33Speaker 3They're going to also, they're going to run, you know, they're going to do more imaging though too. They'll do the image. I don't, I can't do that. That's not in my office. So
46:40Speaker 3some of the imaging can maybe keep you from having to run some of the markers. This is if you wanna stay away from the cardiologist, you wanna see what the blood's showing,
46:47Speaker 3it'll give you a good sign. And then seeing the blood, you might wanna say, hey, might want to go get some imaging done.
46:53Speaker 2This doesn't look good. You may have had some damage going on. You want to see what degree, you know? I mean, what's the degree of when somebody walks in where you're like, holy shit, you need to go to a doctor.
47:03Speaker 2What are you, I'm assuming that's happened where you're like, guy's messed up. His blood,
47:28Speaker 3Then come back in 3 months and let's recheck and see things are gonna, you know, going back in the right direction here. People are gonna run gear.
47:35Speaker 2That that that's the thing. They're gonna run gear. That's just they've done it forever. Like, at least at least, you know, when, you know, when a long years and years ago, there was not as much information at our fingertips. So now if you're running gear and you don't at least do some research, you're just being silly.
47:52Speaker 2put down on paper for some of these guys that are gonna run gear that aren't gonna do the research themselves. What are some of the supplements
48:01Speaker 2that will at least help them that they should be running on a cycle? Okay. Ready? Yep. Do you rank the top 5 and then add more? Okay. All right. Omega
48:25Speaker 3form, that's really important, guys. Triglyceride form. Gotta say it on the bottle. TG form. Triglyceride form.
48:54Speaker 3That's a really good 1. Those are the ones you kind of see. Those are the common ones. They do the job. They do the job. And they stick those guys in 1 bottle and they're good to go. Yeah.
49:03Speaker 3Bergamot, big 1. That's good. Bergamot shifts, and I, again, test this on myself. It shifts the particles.
49:13Speaker 3small to more large. It does kind of, you know, more cardiologists are starting to use bergamot. It's from Italy, by the way.
49:19Speaker 3It comes from Italy. It's from a fruit called the bergamot Most things are If you look at our modern Glutathione
49:25Speaker 0in Italy. Really? I didn't know that. Well, the good stuff comes from Italy. But just most of like the products and cheeses and meats and all this other stuff, you know, you think about it like the origins are
49:37Speaker 0He wants to be Italian. They've been around there for and absolutely no, I'm not Italian. But
50:05Speaker 3liver product. There's a bunch of them, something to kind of help with liver support and bile flow.
50:16Speaker 3Wonderful product, both of them. I'm a big fan. I'm a big fan of both of those. So N acetylcysteine is a great precursor if you're going to take glutathione.
50:28Speaker 3in about 30 minutes, you dump the or inject it however you're to do it. Right? You can do it orally or injection. Glutathione, run the glutathione with the NAC. Really good combo. Great antioxidants.
50:38Speaker 3Number 1 antioxidant in the body. The strongest antioxidant known to the human body is glutathione.
50:43Speaker 2Yeah. So how many how many how much glutathione would you recommend a week, like a week? A week? I usually do it on a daily basis. You do it daily? I do it daily.
50:53Speaker 3Injection? On and off. I run I run bottles. Okay. And I go off of it. Yeah. I go on and off of glutathione.
51:33Speaker 3once or twice a day. I do them in the morning and night. You do it morning and night? Yeah.
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52:46Speaker 0Talked about you just gave us kind of a mix of peptides and supplements, but I just I'm curious. This is a peptide called peptide of the week. So we are talking about some peptide specific questions, but like, give me the rank, the top 5 peptides
53:13Speaker 2Yes. So I wouldn't be right. It's gotta be inflammation, right? So what are the top 5 peptides?
53:22Speaker 3honestly. Right? TB, those are really you know, the Wolverine stack. Amazing. I I think internal health. I think that eventually, though, with the Wolverine, you shouldn't keep running Wolverine before I think you should split that up eventually. Eventually. Right? Yeah, I think so. I think need TB-five hundred every day for a long period of time. Think that they're finding that could maybe
53:49Speaker 0really like that 1 a lot. I think it's getting a lot of attention. JD and I both have been taking, well, I don't know about you, but like I've been taking,
53:56Speaker 0I've started to decide, I wanted to ease myself in a bit. So I've been taking 15 mg a day for the last 4 days. And with the goal, we'll be about we'll be 30 mg a day.
54:07Speaker 3We had Jake Hamilton, and he was kinda recommending stuff. We were both, like, right after we went and grabbed a bottle. Does he what is he I was wondering, like, was there a study done on on that much? Like, why would you say 30 mg? Where does that come from? I'm just wondering. No. Mouth is so much. What he said was,
54:32Speaker 0etcetera, and that was his recommendation. This guy has some type of credentials the owner's license come behind? No, he doesn't.
54:42Speaker 0But if you look at, I mean, well, what do we know about SS-thirty 1? We know that it was up for like clinical trials and close to being FDA approved.
55:18Speaker 0who have like almost like HIV, wasn't HIV patients, but like have muscle wasting disease. Like the whole point of this is 31 was to help
55:46Speaker 0Mean, NAD glutathione, they'll probably be in there somewhere. NAD for sure. NAD glutathione is awesome.
55:52Speaker 3I mean, I really liked the GLP. I think that's doing some amazing stuff. Also, like, I'm finding it's anti tumor anticancer. I mean You're talking about internal. Right? GLP 3, though. GLP 3. Hopefully, the five's coming. And, like, neuroprotective
56:05Speaker 0I mean, there's a whole bunch of benefits that we don't even know from Retta that That we don't even know yet. Right. Yeah. I would throw in TA-one.
56:16Speaker 3so many. It's hard to it's hard to put the top 5 in because there's so many good ones.
56:27Speaker 3obviously you wanna run that- It's for autoimmunity too, by the way. I'm seeing autoimmunity. However it can, it
56:36Speaker 2If your auto immunity is inflamed, it can actually, it's like you're throwing gas on it and living proof of that. I've really toyed around with the TA-one quite a bit. I love it.
56:46Speaker 2I don't really get sick much anyway, but man, when I'm running TA-1D, like you just feel great. Awesome.
57:08Speaker 03 months on, 2 months off. No. Take your blood test. And if you have testosterone, here's 1 here's 1 general rule of thumb is right. Well, the goal the whole point of taking a break, a, is well to let your body kind of rebound.
57:19Speaker 0And, yeah, all of the medical markers, but also your natural, shuts down your test. So you want your
57:38Speaker 0far as I know. What would you tell somebody if 3 months on, 3 months off, give or take, but nobody ever waits 3 months. So that's 3, 2.
57:45Speaker 3I was I tampered with them, you know, starting at 21 years old. Yeah. Well, then. And it was always that was the rule. You go on for 3 months, well, then you gotta go off as long as you're on. So if you're on 2 months on, 2 months off, 3 months on. I mean It's been 3 months. That that's kind of like vague though. It depends on the person, the body, how jacked up. And what you're running. Like, guys are running in trend. Like, trends depends on what you're doing too. And then, of course, like, you know, like, some people maybe they should take a year off. Yeah. Maybe they maybe they only need to take a couple. I mean, it's so case dependent. For sure, your answer would be, Hey, get off until we do enough blood tests that we can test you that you are, like, a healthy individual. Yeah. You can I'd say it's a good idea. Like, maybe, like, you know, run a little blood test before you want to go back on just to kind of say, hey, this is where
58:32Speaker 3gonna look worse. So, you know, maybe you need to wait a little longer, maybe you need to do a few things before you think about doing that. And that's kind of what I like to do with these guys is just to kind of, you know, they want someone to kind of
58:44Speaker 0tell them that. For sure. They need it. They need it. So then the next person is like, yeah, so if I'm a person who wants to do cycles,
58:53Speaker 0when should I get my blood tested? I was talking to somebody the other day and they're like, Oh, I'm about to go get my blood tested and they're at their height of their cycle. And my answer was like, but like why?
59:05Speaker 0What's the point of that? Like what we would, what I would kind of want you to do is take your blood test before you started the cycle. So we see what healthy normal. Yeah. I think that's smart. Let's
59:16Speaker 0do it again. Once you get off to see if you've got back to there, See how you are after- These guys are going to run at mid cycle just because they want to see if anything's way too high. See if they're about to die. Got it. Got it. Because those guys are running
59:29Speaker 3way too much. At the beginning of the conversation, I talked about it. I said, Hey, people are right in the middle of the cycle. I told them, This is not going to look pretty. You're on this.
59:38Speaker 3This is not going to look pretty. Let me give you the heads up because you're doing it mid cycle. You know I mean? Just be ready.
59:45Speaker 3People freak out. You know? They're like, oh my god, I'm gonna die. Well, you did this mid cycle. This does not look good, but, you know, maybe you should do it after you've been off for a while before you want to start. I think that's a great idea, Will. You know? Kind of see where you at when you're kind of yourself in the natural, more in the natural, because we know that going on anabolic, you're going super physiologic.
1:00:05Speaker 2You're to go out of the natural. You're going to see out of the natural response on your labs. It's similar to the degree where, I'm going to just state stupid here for a reason because I think it just needs to be said. Like, if you're going to run gear, you need to do it responsibly.
1:00:17Speaker 2We're not advocating you should or you shouldn't. People do it and let's just be honest. That's what it is. Like, if you don't know what certain compounds do, if you don't know different esters and things like that, you shouldn't be running it. Like, you need to research again, like, you know, when we were younger, like, we didn't have it was hard to find out the answers to these things. Yeah. Literally, you have a phone because we get a lot of questions through this channel
1:00:39Speaker 2of men and like, I'll literally say, you shouldn't be running gear, man. Like, no offense. Like, if you don't know the answer to that, you're not ready for gear. Like, that's that's a silly question. Unwilling and too lazy to actually read and to get the answer for yourself. Asking me that? Like, you could find that in 3 seconds, bro. Like if you don't, don't start, you're not ready. Maybe people don't really trust
1:01:07Speaker 3get a 100 different answers on 1 question. It's like, man, it's pretty shoot. It's a little
1:01:23Speaker 0mean, I you can do them as responsible as possible, but it doesn't mean they're not gonna be bad. It's still gonna be bad for you. Right. And thank you for saying that. Let's
1:01:50Speaker 2don't drink in water and dehydration. I'm not running gear on a crappy diet. Like people think you take steroids and you just get ripped. No,
1:02:01Speaker 2of discipline. That's funny though. Like it's seriously like the general consensus of people that don't know
1:02:07Speaker 2if you take steroids, if I took steroids, I could look like that. No, it doesn't work like that. You can't just get jacked.
1:02:14Speaker 0then real answer is like, you know what? No, but really you didn't really need to take steroids if you just worked really hard and ate right. You could also look like that. Literally throwing some fasting meat right. You can look great. Who are doing steroids and don't look like they are.
1:02:32Speaker 2like you're eating like shit. You're gonna eat like shit, you're gonna look like shit.
1:02:38Speaker 3lot of viewers probably I'm seeing them, they're my patients and I can never reiterate this enough, high vegetable eating,
1:02:45Speaker 3especially when you're cycling because of the polyphenols, the antioxidants, and the detoxification
1:02:50Speaker 3abilities that vegetables have. And I know some guys can't do it. I know sometimes we struggle with vegetables,
1:02:56Speaker 3but I mean, are very healing Why you guys looking at me? Too. Why are we looking at you, JD? You know? But I'm just saying, like, you know, diet is so important. It's it's extremely important. Hydration is so important. Hydration. Hydration.
1:03:11Speaker 3the RBC hemoglobin and hematocrit is gonna be up and you can have that. I see it elevated even for a lot of people. When you see RBC hemoglobin and hematocrit elevated on someone who is not on steroids or does TRT, that's a sign of dehydration.
1:03:30Speaker 3I mean, that's just a sign of dehydration. It is not always like, Oh, I don't drink enough water. It's a sign of cellular dehydration.
1:03:38Speaker 3Sometimes people all see that pattern. They'll realize you could get 2 gallons a day. Said, well, either you're drinking too much water, number 1, or it's you're inflamed and the cells are dehydrated. Sure. The cellular dehydration that we're talking about here. The water needs to be in the cell. We talked about 30,000,000,000,000 cells. You need water too to make ATP. You need oxygen to make ATP, glucose, you need thyroid hormone to go into that cell. In that cell, you got vitamins, minerals, antioxidants, and the mitochondrial,
1:04:15Speaker 3sugar, water, thyroid hormone, be a dysfunction. You can have nutrient deficiencies that could be a dysfunction that
1:04:29Speaker 2So like, what do you recommend? Because I know a lot of, like if you're drinking general water, like you're not really getting hydrated. You need Celtic salt over. Yeah, it's good to put some Celtic salt in there. Like, a lot of people don't know that. Like, you need to, like, have minerals in the water because it's just even the water sucks.
1:04:43Speaker 2Jeez, dude. Like, you pee all the time. Yeah, like it's because you're not, the water's not doing what you think the water is don't want go drink Yodosian water. Yeah. Like I start off the morning, I'll go and I'll like lick my finger. My wife, give me a little salt box. He's so cute. And I'll like lick and then use a both Celtic salt, let it soak into your tongue. Good for you. And then you start with water. That's literally the best thing. Like
1:05:04Speaker 2if you don't like try saltwater, it's the best pre workout there is. You get so much energy off of that. Yeah. And that's what I mean. People laugh at me like your workout. It's not a pre work. I'm like, listen, I've doing it forever because I fast a lot. Like I'm on a 48 hour fast now. This is full of Celtic saltwater. And like my sons now go, dad, is there salt in that water? My
1:05:23Speaker 2wife always laughed. My little 2 year old goes today, this morning, he goes, dad, there's salt in that water. I'm like,
1:05:40Speaker 2don't do that. You start your day with saltwater and it's huge. Like you need to get hydrated after you sleep. Yeah, I agree. It's huge. I agree. Like those are simple things. We wake up pretty dehydrated. We do.
1:06:00Speaker 2I had struggled with cortisol recently and that opened up my brain to a lot of just reading about cortisol. I wasn't super intrigued by it.
1:06:12Speaker 2cortisol, I don't have coffee for an hour because it spikes your cortisol. Like what I'll do is I pray and I read into you my whole
1:06:27Speaker 2I mean, whether again, I always say this, well, here's it all the time, but if it's please SIBO or not, it works for me because it's working. Yeah. Mean,
1:06:37Speaker 2everybody needs to do. Like we talked about in the very beginning, our food sucks. This is what it is.
1:06:44Speaker 2We need to have a good diet because we have to scramble through shit food to find good food, man. And,
1:06:54Speaker 2was on a sweet spot for years, man. I was just feeling good, dude, dude. And, but man, I got knocked on my ass in the last 6 months. You know, we ran blood work, reran stool chest and we've been working through it. You know, I've sat down with Scott for 2 hours going through my blood work. Finally said, I think I'm throwing in the white towel, dude. My brain doesn't even like, I'm
1:07:18Speaker 2you get it? Did you go to lab yet? No, I need to do that. I was going to wait, you know? So, but
1:07:24Speaker 2like we've been, I've been working with you and it's been great. I mean, it's been eye opening as you listening to this podcast,
1:07:31Speaker 2he's intelligent. He's 1 of my best friends. I love him to death. And these are the people that you need to have run your blood work because they know what they're talking about. If it's obvious,
1:07:40Speaker 2not to say it, medical doctors don't, but they'll run small little panels that show a piece of a picture and you're not going to see the picture. You need,
1:07:47Speaker 2again, we say it all the time, but you don't have to feel like shit. You should have a sex drive. You should have a clear head. You should feel good.
1:07:56Speaker 2These are things that like, I think society has purchased the lie of I'm getting older and I don't have a sex drive and I'm feeling like shit. Like, that's just so wrong. Now it takes time and blood work and stool tests,
1:08:11Speaker 2But then little, little, little things that you implement in your life, little disciplines, little things that compound drinking salt water, right? When you wake up implementing these little things in your life that just will yield health. It can make a huge difference.
1:08:24Speaker 2Geez, just sleeping is a huge difference. I mean, you know what I mean? Yeah, definitely. Sleep something. Yeah. So
1:08:31Speaker 2guys, you're going to run gear. That's up to you. We don't care if you do or you don't, you're a grown man, but if you do,
1:08:48Speaker 2Please, for the love of God, if you're going to run gear, at least of know what the gear does. Don't just like your brother, your buddy at the gym told you to run some D ball and certain amount of Milgram. You know, it's like,
1:09:33Speaker 0tell us if we want to put out your information. As freely. We'll find you anyway, but like, I mean,
1:09:40Speaker 2you know, we've been blessed. I've known Scott for a long, long time, man. Geez, like early twenties. And
1:09:48Speaker 2you know, we've, we've gone through drug addiction together. We've done through some stuff. It's been life and, to see where our life's at right now, man, it's a blessing, man, to be able to work with people.
1:10:02Speaker 2lean on some of our experience, your expertise, for sure, of just trying to be healthy, man. And it's a blessing, you know, and this podcast is getting out there. We've just had the blessing to be able to have
1:10:12Speaker 2rad guests on the show that are really good at what they do. We're going to have that water gal on. I'm really excited to have her on. Like she's gonna, it's a Kagan girl that just,
1:10:25Speaker 2didn't invent Kangen water. Yeah, she started knew all about it and we were like, dude, that's rad. You should come on the show and like drop that because like, we didn't know any about that stuff.
1:10:42Speaker 2excited to hear it too. Yeah, that's a lot of stuff. And like, we, like, we get to lit lit sit here with guys like you and learn. I mean, it's the best. I mean, you alright? You got a blast. We love this stuff. Good stuff. Good stuff. So Same to me. It's good to be invited. Good to have you back. We'll obviously have you back many more times because we love you. Other than that, we want to say anything, dog? No. Thank you. We'll
1:11:01Speaker 2see if we want him to be found. We'll talk to him because he's already very busy. He's out there. Yeah, you can find me.