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Ep 52 · 38:57

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0:09Speaker 0What is up, everybody? Welcome back to the Peptide of the Week podcast.
0:13Speaker 0I am your host, JD Denham. And now sitting right next to me is my buddy and my cohost,
0:19Speaker 0William T. Haws.
0:21Speaker 0Dude, what's up, man? What's up, dude? It's Friday. I
0:25Speaker 0was thinking this morning, man. We got a lot going on. We're juggling a lot. And, you know, Andy, who's our videographer,
0:32Speaker 0sent us a cool video that I was looking at this morning.
0:35Speaker 0So I want to kind of take a little bit of a side note and ask you a little bit of a different question today. We are coming up at the end of a year and we're going into 2026.
0:44Speaker 0Let's let everybody at home know what are some of the things that you're grateful for?
0:49Speaker 0Boy. Because you got a lot going You got a lot going on, dude. And I've known you a long time and your life has changed pretty radically
0:55Speaker 0well, I've known you to be a long time. So And I thought I'd throw that at Well, you the 1st simple answer that I, like, start every day with is like,
1:06Speaker 11st of all, I guess I'm grateful I have a brain and
1:10Speaker 1arms and legs. Right? Grateful I'm born in America. And frankly,
1:16Speaker 1you were in America being a white male. I guess I am I've hit the lotto already. And
1:21Speaker 1that is when people may have some other
1:24Speaker 1problems with that. Now I don't think that
1:26Speaker 1white males should be,
1:29Speaker 1I don't know, should be discriminated
1:31Speaker 1against.
1:33Speaker 1But, hey,
1:35Speaker 1life is good from there. Right? I live in a gorgeous place.
1:39Speaker 1So those are the things, I don't know, every day I'm like, thank God that I can think,
1:43Speaker 1right, that I have my legs.
1:45Speaker 1But
1:46Speaker 1I am at a point where, I guess, my whole over 10 years of addiction and being miserable and having such a tiny little life and it was just me,
1:55Speaker 1all I wanted was to have
1:57Speaker 1a bigger life and
2:00Speaker 1have friends
2:02Speaker 1that cared about me and like a wife and kids
2:05Speaker 1and
2:07Speaker 1yeah, and be busy and just have a lot of things going on, right? And people like trusting me.
2:12Speaker 1And then now now I basically have that. Yeah.
2:16Speaker 1And
2:17Speaker 1still I get ungrateful of like, God, I just want you to have these friends and people. I hate them and people care about me.
2:24Speaker 1But I often am able to step back and go,
2:28Speaker 1that's dumb. This is what I asked for.
2:30Speaker 1This is what I asked for, and I'm living it. So, dude, I don't know. I am grateful that I have a woman that loves me for me
2:39Speaker 1and is supportive
2:40Speaker 1with everything. I'm grateful I have a
2:43Speaker 1kid in my life that I can
2:46Speaker 1be a good influence to.
2:48Speaker 1Even though he's not my child, but that doesn't matter. He has had not great influences and
2:55Speaker 1I don't know. Grateful for all this, all my friends,
2:58Speaker 1and just God working
3:00Speaker 1in crazy ways. I
3:03Speaker 1don't know. I mean, I guess that was the turning point is
3:07Speaker 1Finding and and it was really fine when finally get a god and say, everything will be okay as long as I just kind of put some hard work in, right, and just take 1 foot in front of the other and don't try to just force
3:18Speaker 1manipulate
3:19Speaker 1everything to my will. You know? Sure.
3:23Speaker 1But it still takes hard work. Daily. It still takes a daily,
3:27Speaker 1like you say, paying the tab. Yeah. But
3:30Speaker 1I don't know, man. I'm grateful constantly for for
3:34Speaker 1everything
3:34Speaker 1in my life. What's on with for everything.
3:38Speaker 0Yeah, there's sometimes,
3:39Speaker 0you know, with my kids and I'm thinking, I've had these huge moments of gratitude more than ever in the last,
3:45Speaker 0specifically few months. There's a lot of cool stuff going on, just family and just life, business,
3:50Speaker 0whatever. It's just been a good year in regards to that.
3:54Speaker 0Never take your eyes on the prize, man. Anybody
3:57Speaker 0that's listening to this know that Will and I have both been sober for a long time and some of the things that we work with are men that are newly sober. 1 of the lessons, I don't know if you do this, but 1 of the lessons I have my, sponsors start with is, when your legs hit where your feet hit the ground, as you're going, whatever you're going to do, go to the, take a, use a restroom or you're going to push coffee, whatever. As soon as your feet hit the ground, you start going through the role of the things that you're grateful for. It's been amazing. It's been amazing to kind of start those things off, man, because the human brain cannot be
4:26Speaker 0negative if you're sitting in a pile of gratitude. So good little lessons to kind of, it's good to start like that just because man, we are coming to an end of the year. It's obviously common sense. Everybody has
4:38Speaker 0goals
4:39Speaker 0and things that they're gonna do in 2026
4:42Speaker 0and new year, and unfortunately,
4:44Speaker 0most don't follow through with it.
4:47Speaker 0Anyways, but we'll kind of go into a segue of what we're talking about here because some of these things will actually have been studied to actually help you- Help achieve some goals. Help you focus and achieve some goals, ironically. It's actually some of the stuff that I read about it, so it's interesting. So today we're gonna talk about
5:01Speaker 02, they're not peptides, but they are in that category. We're going to talk about Tesofensine
5:07Speaker 0and then Methylene Blue. Let's talk about Tesofensine
5:11Speaker 01st. I know you know, both have taken it and a lot of people love it. It's
5:17Speaker 0monoamine
5:18Speaker 0reuptake inhibitor. The hell is that? It's
5:22Speaker 0gonna boost your dopamine,
5:24Speaker 0your mood, your serotonin.
5:26Speaker 0It's really just gonna be for people kind of comparable
5:29Speaker 0to an antidepressant
5:32Speaker 0in many ways. So let's tap on that a little bit. Let's tap on that because antidepressants are huge,
5:38Speaker 0especially in The United States. Many Yes, people are they on are. So let's dig into that. That's why I wanted to start with Tesofensine. So tell us a little bit, like, always a little bit about what it is, who should take it. So some and and and I guess us too sitting across from the table, like, we have different,
5:52Speaker 1very different personal experiences with this. Yeah.
5:55Speaker 1I thoroughly enjoy Tesofensine and he hates it. So it all depends on your brain chemistry. So there are basically Tesofensine, if we wanna make this really simple, it's a triple monoamine reuptake inhibitor.
6:07Speaker 1Those triple, okay, so it is going to basically increase your serotonin,
6:11Speaker 1your dopamine, your norepinephrine,
6:14Speaker 1those 3 big neurotransmitters. Mood, motivation.
6:16Speaker 1Serotonin is your happy but calming neurotransmitter.
6:20Speaker 1Dopamine is happy but
6:23Speaker 1little bit of energy, and norepinephrine is happy and excited
6:27Speaker 1neurotransmitter.
6:27Speaker 1So those 3 are being and Zoloft
6:31Speaker 1is a SSRI, serotonin reuptake inhibitor. Naltrexone and Wellbutrin are dopamine reuptake inhibitors.
6:38Speaker 1And norepinephrine
6:40Speaker 1just alone isn't very common, and I don't really know a
6:45Speaker 1brand name for that because it's not really a common thing for people just to take a single amount of. But these are not these are actually more than just those 3 put together. Right? If you just got those 3 from the pharmacy and took them all together, right, Tesofensine would actually work better and be
7:02Speaker 1more of
7:03Speaker 1of how your brain naturally reuptakes
7:07Speaker 1well, inhibits the reuptake, which is basically the wasting of of those 3 neurotransmitters.
7:13Speaker 1So it's actually better than just taking those 3 combined.
7:16Speaker 1It's a little bit stronger than than taking those 3 combined. But bay but what that's gonna do, yeah, you I wouldn't take it at nighttime because it's gonna give you energy. You might not be able to sleep very well. Yeah.
7:28Speaker 1You will be happier. You'll be yeah. It'll make you well, I'll speak for myself because he didn't have this this. But in general, the point is to
7:38Speaker 1make you make you happier, make you more content,
7:42Speaker 1not give you anxiety,
7:43Speaker 1although because of the serotonin, it helps with the anti anxiety. Those people who are very prone to anxiety, it might give you some it might activate some anxiety.
7:54Speaker 1They And- call it the happy drug. They call it the happy And why it is why are we talking about it, right, in the realm of, like, supplements and fitness?
8:02Speaker 1Because
8:03Speaker 1it is used as a appetite suppressant.
8:06Speaker 1Why? And unlike some of the GLPs that physiologically,
8:09Speaker 1you know, they work,
8:11Speaker 1in your body, this is all about your brain. So essentially, it is making your your brain just content.
8:18Speaker 1Alright? So you are not looking for any dopamine spikes from food. Yeah. Right? That's kind of a huge reason why a lot of people eat and especially eat sweets- Yeah, emotional. Is because and whether we know it or not, right, we tend to we want that sweet and bam, my brain feels good. This literally will make food and seeds not be as good, but it also makes you feel Because you're satiated. I'm satiated. My brain is satiated and I'm not looking for any extra happiness spikes.
8:47Speaker 1It's this is why,
8:49Speaker 1I don't know, I mean, my dad tried to quit smoking and was taking Wellbutrin
8:53Speaker 1to quit smoking.
8:55Speaker 1Naltrexone
8:56Speaker 1is a thing in
8:57Speaker 1the treatment
8:59Speaker 1business that helps with cravings. Okay? And that does well dopamine reuptake inhibitors. And why? Because it makes your brain feel content. You're not looking for that thing to satiate a craving.
9:09Speaker 0Which is interesting. Let's sit on that for a 2nd because I
9:12Speaker 0think 1 of the biggest struggles that most people have, especially probably in The United States,
9:17Speaker 0is cravings.
9:18Speaker 0We've both worked with numerous people in regards to diets and exercise and stuff like that. 1 of the biggest things that I was up against with people were men that I was working with was sugar,
9:28Speaker 0sugar cravings alone. You know, not let's talk, not even talk about the addiction of like other drugs and alcohol and stuff, but just sugar is 1 of the worst drugs.
9:36Speaker 1And it's been I've talked with a lot of people that take it in that it changes the cravings to that stuff. That's pretty powerful. It's really powerful. You know I mean? That, it changes the cravings. Right? You don't they don't you will be on it and go, this ice cream is just not doing it for me. It just does not taste as good, and it's because your brain just doesn't care for it anymore. So similar to GLP-three.
9:58Speaker 1Yes. Yeah. Right. It has some of those similar,
10:01Speaker 1yes,
10:02Speaker 1brain effect, new new nootropic effects as GLP-three. Also, you know, it's an interesting thing. So those people who so men, if you or men and women, if you,
10:12Speaker 1if you want your sex if your sex drive is lacking a little bit and you're the person who eats
10:17Speaker 1sweets at night before they go to bed, cut out the sweets and watch your sex drive increase.
10:23Speaker 1Because you are choosing sweet to get to get that
10:26Speaker 1spike of happiness. Right? And and that's easy. That's just you comfortable.
10:30Speaker 1You comfortable by yourself. Oh, no. I've got have Twinkies are sex. Twinkies are sex. Right. I mean, if you have a significant other that you're there next to, try cutting out the sweets and your body will be looking for some other way to be happy. Alright. Let's talk about that for a 2nd. So would you say so sweets, would that what would would, like,
10:47Speaker 0you know, God sweets do the same thing, meaning, like fructose or like, fruit?
10:53Speaker 1Yes.
10:53Speaker 0Kind of similar. Mean, it kind of probably is the same. So don't eat fruit before you before you go. You're looking to get some love? Yeah. Yeah. Don't eat some fruit? Yep. Eat a steak? Eat a steak.
11:02Speaker 1Absolutely. I would really say that. Also, if you try to burn any fat,
11:06Speaker 1or work on your physique, don't eat fruit. We understand everybody's like, hey. Fruit fruit is healthy. Okay? Now fruit is healthy because it has good vitamins and minerals, but
11:16Speaker 1a banana is the same thing as eating a Snickers bar when it comes to your physique wise. Right? They're both sugar. Okay. If you eat them before you go to bed, you're not gonna burn that sugar off. And that sugar is now going to since you don't use it, it's gonna go, well, shoot, this is perfect storage
11:33Speaker 1calories, and I'll just convert this to fat and keep it on me in case I eat it and I'm starving or or cold later
11:41Speaker 1later on down the road. So fruit should be eaten,
11:44Speaker 1in the morning when you get those vitamins, minerals, and you get to burn use the energy that's providing you.
11:50Speaker 1I'm gonna say a lot of people don't fruit. Here's another 1. Fruit. Don't eat a full meal and then eat fruit on top. You will be gassy because all of that food needs to the fruit goes in there in this hot,
12:02Speaker 1in this hot, unvented
12:04Speaker 1climate while your food is digesting, and this fruit is going to ferment
12:09Speaker 0before it gets digested Yeah. And will cause gas in your stomach. Yeah, so on the carnivore or like a ketogenic diet, and you know, that would just, man, in some of my comments when I'd post certain things in about fruit, man, you wanna get some people mad talking
12:24Speaker 0about how the fruit's not as healthy as you thought it was healthy, Especially today's fruit, probably. It's like And they're not getting organic. It's just I Alyssa gave Jack some apple the other day. He's like, it doesn't taste like anything, and I took a bite of it. I'm like, it doesn't. Like, what the hell? What the hell, bro? Just the fruit sucks. Man, if it's not organic, it's Have you heard about those apples that are flavored,
12:45Speaker 1like pink lemonade?
12:47Speaker 1Brandy brought some in the other day. Actually really did it really. And it was pink. Once you bit into it, it was pink.
12:53Speaker 1But talk about more genetically engineered fruit.
12:57Speaker 1Real bananas don't look like that, by the way. No time in history has a real banana ever grown like that large.
13:05Speaker 1They really look to they're about this big and are not all the same perfect shape either.
13:11Speaker 1Yeah, but I guess fruit isn't Fruit is good for you. It carries all these vitamins and minerals. Again, antioxidant properties, certain fruits are better, right? But as far as I'm talking about
13:20Speaker 1losing weight, maintaining physique, there's a good there's a right time to eat them and the right time not to. And it still is sugar.
13:27Speaker 0So in regards to Tesofensine,
13:29Speaker 0some of the stuff that we've read and we have a lot of people that have taken it, you've taken it, you can kind of see if you agree with this, but it's gonna improve your mood, clarity of thought,
13:39Speaker 0and
13:40Speaker 0it's been known or studied for to help make better decision making in
13:46Speaker 0that part of your brain. Isn't that crazy? That's interesting. That is interesting.
13:50Speaker 0Because of your focus.
13:52Speaker 0So if you're somebody that's not disciplined, it helps a little bit with some of the discipline. I mean, you still have to always eat right and exercise if you want certain things to happen well, but it
14:03Speaker 0kind of helps to get the ball spinning downhill is a better way to say that. Mean, is it's
14:08Speaker 1very helpful for delaying gratification because, again, you're not looking for gratification.
14:12Speaker 1Yeah. You know what I mean? You're just not looking for those spikes
14:16Speaker 1of artificial
14:17Speaker 1happiness
14:18Speaker 1that are all around us at all times. Yeah. Because you're already pretty discontent with yourself, right, which is like the ultimate
14:27Speaker 1spiritual
14:27Speaker 1experience to be, you know, is,
14:30Speaker 1right. Just to be completely happy with yourself and not need anything,
14:35Speaker 1and then you make damn good decisions, damn good at all times. So not only is your brain gonna be clearer and more awake I mean, 1 1 thing I noticed, I don't know if you knew me,
14:46Speaker 1like, I guess there maybe there were changes in my life, but I used to like to take naps.
14:52Speaker 1And I look back, and now I've taken started to take Tosapiensin. Now other things in my life have changed also, but
14:58Speaker 1napping, even if I'm dead tired, is the last thing that's on my mind. Interesting. Even if I get sleepy Are you taking it now? I am taking it now. Because you don't feel like taking Nathione too. No. Most people. No, I don't. That's good. No, still, if I eat some food, if I eat a big, like- Carb loaded. Yeah. Carb loaded meal, like I will fall asleep. And I mean, believe me, I could fall asleep at any 2nd during the day. Give me 5 minutes sitting up in a chair. I could fall asleep, but I don't want to because
15:22Speaker 1I would rather live
15:24Speaker 1life.
15:25Speaker 0Yeah. You have success with me. I
15:28Speaker 1think I would rather sleep because there was probably a slight bit of depression,
15:32Speaker 1and I think that the Tesofensine is taking care of that. Well, that's some of the point of it. That is kind of the clinical- There's so many people taking antidepressants.
15:41Speaker 0I mean,
15:43Speaker 0gosh, almost most people, but a lot of people. It's so freaking common.
15:48Speaker 0So I'll give you my experience. So Will's given his experience and I would say most people I talk to have similar. I've had so many people, it just makes me happy. It just makes me happy. My experience is different. So when
15:59Speaker 0we, went to Cancun with my family,
16:03Speaker 0for my cousin's wedding, blah, blah, blah, and I just started taking it because it read well. I was studying it and it read well, I'm like, sounds pretty cool. And so I started taking it and I did not have that experience. I was in Cancun and
16:17Speaker 0felt off. I felt just
16:19Speaker 0lack of focus, kind of cloudy headed, just like I hadn't had my V 8. And I was starting to go,
16:26Speaker 0Why do I feel like this? It almost was the opposite of affection because I felt lack of motivation, which I'm always motivated to go to the gym. I was like, I had to make myself. And I start peeling back things, what I've taken, what I've changed, and I'm like, Is it the Tesofensine?
16:41Speaker 0Not thinking it would be that because it read so well. So 3 days into it, I pulled that out and literally within a day I was back to normal. So the point of that is very, again,
16:53Speaker 0we are so radically different and most people have that experience, but you know, I've always been a little bit wired different. Like, if I, you know, when I said to blow, I would not be so talkative, I'd be kind of quiet. You know? So it's kind of like the opposite. If I take Nyquil, I can't go to sleep. Okay. Stuff like that. So kind of maybe a-
17:11Speaker 1Which is common, I guess, it's just common people who like upper I mean, this is what I mean, for people who actually have ADHD
17:18Speaker 1Mhmm. You know,
17:19Speaker 1Ritalin and Ritalin and and Adderall finally
17:24Speaker 1calm them down. Yeah. And make their brains, like, be able to focus because it's not just like gears,
17:29Speaker 1you know, you'd see this is my visual on those.
17:32Speaker 1Think about gears, like, kinda working, fitting together, and then they start going a little bit faster, then the then then the nut, ping, spins off. They just start going out of control, spinning. Right? That's what
17:44Speaker 1I felt like on when I just take straight up uppers.
17:47Speaker 1Too much. Just too much. Brain spinning. So anyway, that's what kinda it slows slows a person with ADHD. Maybe you have a little bit of that
17:56Speaker 1Maybe you'll have a little bit of that in you. But the point there is his brain chemistry is different.
18:03Speaker 1Right? Like, everybody's brain chemistry is different. Well, it's like- You probably had an end, which I guess is a good segue into side effects
18:11Speaker 1what not to do. Dangerous. So because this is a triple reuptake inhibitor,
18:17Speaker 1the warning is people, I
18:21Speaker 1wouldn't take any if you are taking an antidepressant. Right? If you're taking SSRI or
18:27Speaker 1SNRI,
18:29Speaker 1I wouldn't
18:30Speaker 1take those and take desofensine
18:32Speaker 1because you're just doubling up on that. There such thing as, like, serotonin sickness. And my guess is that you probably have a ton of serotonin, and it and it just overloaded you.
18:43Speaker 0Something was off.
18:45Speaker 0And so it's not for everybody. Yeah. Think you were telling me kinda recently.
18:49Speaker 0So we were thinking about doing Tesofensine a few weeks back, and I think you were saying that we were talking about it in my experience with it. And I think you were saying, bet you if you kinda let it kinda ride a little bit, would ironed out. Yeah. You know? Or started lower.
19:01Speaker 1Yeah. Started lower and then kinda worked your way up.
19:04Speaker 1Speaking of dosing, I would say that 500 micrograms,
19:07Speaker 1that's what I take a day. But I would say about, you know, maybe those who think they're sensitive to things, 2 50 micrograms a day to start.
19:16Speaker 1Taking the 1st 0.5 of the day, again, so if take it at night, it may make you not sleep. But the range, 250 micrograms to 1000 micrograms.
19:25Speaker 1K? I have taken 1000 micrograms,
19:28Speaker 0which for what I have is 2 pills, and I'm fine. I just have a little extra energy. I just feel like I just don't need that that much, and 500 is good for me. Interesting. Well, it's funny because the way that you're explaining this is how I feel on Modafinil.
19:42Speaker 1Okay.
19:43Speaker 1Because you know I love Modafinil, but do you feel like that on Modafinil? I get too that is too much for me. Like, I can't I don't like taking more than a full I mean, more than 0.5 a pill. Oh, wow. Yeah. Oh, man. I've taken 2. Yeah. So that is the difference in our brain chemistry.
19:59Speaker 0Yeah. Like to be I took a midafinil before this. I take it every time I would do a podcast because I feel razor focused. Yeah.
20:05Speaker 1And for me, if I took a if I took a full midafinil
20:08Speaker 1on a pretty empty stomach, right, and maybe drink some coffee, I would feel like kind of cracked out. Oh, wow. That's just true. And like as you do, when you take too much stimulant,
20:18Speaker 1I would get kind of her kind of jittery and almost hypertensive and withdrawn
20:22Speaker 1because I don't feel good. Yeah. You know? There's always trap, bro. Everybody's different, man. Everybody is different.
20:28Speaker 0It's just tough. So it's like so when you hear some dude on TikTok saying that you should do this, you should do that, and,
20:33Speaker 0just do the damn research. Not really the research. Do are doing the research. Like, we've tried it. We we,
20:39Speaker 0we try it. We study it. We try it. We talk to a lot of people. And the research is is yourself.
20:45Speaker 1Because you're not gonna get the same effect. Always just established it. Yeah. Absolutely. And if you just read on a piece of paper,
20:52Speaker 1well, cool. That's what it
20:54Speaker 1might do or that's supposed to do, but who knows until you actually try it.
20:59Speaker 1You're all a science project. So there you go. I'm a fan of I'm a fan of it. I've said the Most are. Most people love it. And but, again, I guess I have taken antidepressants in my life. Every
21:10Speaker 1rehab I went to,
21:12Speaker 1I remember I would
21:14Speaker 1be in rehab, I'd get off drugs and be like, Man, am I depressed. Oh, really? Duh. I always felt great when I finally got off drugs. Yeah, I
21:20Speaker 1would feel great.
21:22Speaker 1But as I turned life,
21:25Speaker 1would get definite bouts of depression for sure.
21:28Speaker 1And so they would put me on antidepressants
21:30Speaker 1and then of course, you I would just stay on them. Yeah, you're holding off. Ultimately, I got off, you know, especially like serotonin Zoloft.
21:39Speaker 1Yeah. The worst part of that is like the brain zaps. Well, the worst part of that
21:43Speaker 1is just not being able to be happy. Right? When you're getting off of it, you do go through a week period of like, damn, dude, I'm not happy. So you do wanna wean yourself off. But 1 of the noticeable side effects is brain disaster. Your brain kind of just go like
21:57Speaker 1you can be, let's say if you're walking down the stairs, you might just lose track of 0.5 of that step you took and good thing there wasn't an obstacle you need to
22:04Speaker 1avoid really fast because it wasn't gonna happen. Off that stuff? Holy crap. That sounds scary. No. Frankly,
22:10Speaker 1somebody like me, I don't really mind them. I think they're kind of fun. But
22:14Speaker 1my girlfriend was looking at it and was like, oh my god, this look at this girl on TikTok or whatever. She she's like, The brain zaps are the worst side effect. And I was like, Oh my God, she's never actually withdrawn from
22:25Speaker 1anything real, Yeah. Brain zaps are nothing. Hell,
22:29Speaker 0can even induce them.
22:31Speaker 0Which I would do. Because I've never come off Xanax, I've seen some people look at Xanax. Is gnarly. That's another 1 that just is I was never into Xanax. There was 1 drug that I wasn't
22:41Speaker 1into. I mean, I hate Opiates win.
22:43Speaker 1Opiates is the most miserable thing in the world. Although you cannot die from that withdrawal. Alcohol. Whereas alcohol and and See, someone come off alcohol, shakes Oh, will it's bruise. Those ones you die. Yeah. Because of seizures.
22:55Speaker 1Crazy, man. So don't do drugs. Well, there you go. Tisofensine.
23:00Speaker 0Most people like it. I do not, but it doesn't matter. You should try it for you if you're somebody that, you know, most people I will tell you straight up, they're like, It just makes me feel happy. Yep,
23:10Speaker 1happy
23:12Speaker 1being a drug. You know, it's not like this super euphoric like, oh, yes, I'm high.
23:20Speaker 1It's not like that. Right? You don't and I don't find it
23:23Speaker 1addictive. Now now, again, like I just said, it's coming off of serotonin,
23:29Speaker 1coming off of like an SSRI
23:31Speaker 1can pose some problems. Now, Tesofensine
23:34Speaker 1will has the capability of doing the same thing. So
23:38Speaker 1I would say it's either something you wanna do and just stick with.
23:43Speaker 1Although, just for example, like, I've just spent the last 5 days
23:46Speaker 1not doing it because I forgot. Mhmm. And I definitely didn't have
23:52Speaker 1any of the withdrawal symptoms that I would have coming off serotonin.
23:55Speaker 1But theoretically,
23:57Speaker 1you should have to have some withdrawal symptoms.
24:01Speaker 1So long as you take Yeah. Longer you take it and the higher dose you take, right, the more potential withdrawal symptoms you have.
24:09Speaker 0Right, let's jump into Methylene Blue, which we
24:14Speaker 0took a little while before us to come around to it. I didn't really study it because, you know, when you and I 1st started talking about it, you had said some things that you had dug into it, so we ended up not
24:25Speaker 0getting it.
24:27Speaker 0But now we have decided to. I just started taking it about a week ago, I can give that experience, but it's been my 1st time taking it. Tell us a little bit about what it is and why we who take who should take it? Yeah. Methylene Blue is
24:38Speaker 1Methylene Blue is the thing that is it's a dye. Right? Still used in, like, modern science today
24:45Speaker 1to dye like microbes. So look in the microscope so you could see things better.
24:49Speaker 1But and it was 1 of the it's shoot. It's 1 of the 1st drugs drugs, like, ever ever made back in the 18 hundreds, and actually was used as, a malaria
24:58Speaker 1medication.
24:59Speaker 1But
25:01Speaker 1it's
25:03Speaker 1who should take it? Like, it is being used right now for, like, in clinical settings for
25:10Speaker 1oxygen,
25:12Speaker 1to help oxygen travel throughout somebody's blood. There's rare conditions where
25:16Speaker 1oxygen,
25:17Speaker 1even though blood is flowing just fine, oxygen isn't flowing. Okay?
25:21Speaker 1And so it's been used in hospitals for that. It's also being used kind of off label
25:28Speaker 1in emergency
25:29Speaker 1medicine for patients with going into shock, where their blood pressure is lowering.
25:35Speaker 1It does the opposite of any pump
25:37Speaker 1drug, right? So
25:39Speaker 1any pump drug that you take is a vasodilator,
25:42Speaker 1opens up your blood vessels, right? This is going to restrict your blood vessels, therefore making your blood pressure higher. So those people who are in shock and blood pressure is lowering and is going to very, very dangerous levels and it's too low,
25:57Speaker 1it's gonna kind of close-up your veins and cause more pressure in your blood. So blood is gonna flow, I don't know, the veins will be more rigid and blood pressure will rise to healthy levels.
26:08Speaker 1So the takeaway there is if you're trying to get a huge pump at the gym, Won't work. Probably not the best thing to take. Yeah. Right. Now it is is gonna help with oxygen and blood. K? So oxygen
26:19Speaker 1is the lifeblood of of of blood. Right? Like, that is what the hyperbaric chamber does. Yeah. It is basically the same you like, you take Methylene Blue if you're a athlete
26:29Speaker 1training
26:30Speaker 1for the same reasons that you would train do high elevation training. Right? Or hyperbaric
26:36Speaker 1chamber training because it's going to oxygenate your blood, which in turn gives you better performance,
26:44Speaker 1stamina,
26:45Speaker 1muscular stamina. But also, so there's the physical
26:49Speaker 1benefits. But also it is
26:52Speaker 1pretty similar to Tesofensine where it's gonna affect those 3 neurotransmitters also. K? So it is a nootropic
26:57Speaker 1as well. Brain function. And it's gonna help your brain function. Mood, it's gonna it's gonna work on those 3 neurotransmitters
27:03Speaker 0also. Helps, like, stabilize emotions is what I read. That's interesting. So if you have a so, man, if you have a sensitive
27:10Speaker 0bride, maybe give her some Methylene Blue. Just joking. Joking. Don't
27:15Speaker 1put it in your pee. The problem is, yeah, she's gonna know.
27:18Speaker 1You just took it and,
27:20Speaker 1your pee was blue. I never I've never seen anything like it. That can be an alarming side effect, folks, but that's Like, real blue. It's okay. That's normal. Your tongue, you see them a lot. Like, they're usually in pills. Well, shit pills, liquid, or troches, which is like sublingual
27:37Speaker 1tab. Yeah.
27:39Speaker 1It's pretty clear who's taking them if they open their mouth and stick their tongue out because it will be blue. Yeah. That's normal. That's okay. But, yes, mental clarity,
27:47Speaker 1those of us getting older, it's right, some neuroprotective.
27:50Speaker 1Yeah. Those who are losing, yeah, losing memory, you know, I forget simple words sometimes.
27:56Speaker 0You're right? How
27:58Speaker 0do you spell the the the
28:00Speaker 0getting old such, man? 1 of my favorite quotes is, youth is wasted on the wrong people.
28:05Speaker 1Yeah,
28:06Speaker 0that's true. Yeah, I so I started, what I was starting to read about, because we didn't have it for a long time, then so many people were asking for it. Yeah, you know? And so I, yeah, I hadn't studied it because you and I had talked about it for bit. So I started digging into it. That was why I wanted to try it just because as you get older, our brain, our mitochondria starts to obviously
28:22Speaker 0not work as well. So it helps it be more efficient in regards to just getting old. It's good to boost, like it has antioxidant
28:30Speaker 0properties. So like in regards to like,
28:33Speaker 0you know, what antioxidants
28:36Speaker 0do is going to get rid of like free radicals, like toxins. I mean, we breathe in just crap. Yes, you know. Like just eat crap.
28:44Speaker 0So it's gonna help with that type of stuff. So that's kind of why I started to take it. Yep. I'm feeling older. Brain feels a little bit slower.
28:52Speaker 1I hear you.
28:54Speaker 0I'll let you damage that we have both done to our brains. Yeah. My memory sucks, dude. Yeah. Was yours? Yeah. Mine's bad. It's good. My
29:02Speaker 1short term memory sucks. My long term memory is pretty good.
29:06Speaker 1You know? I don't know. It's like the recollection of words is the that's the main thing that kills me sometimes. Yeah. But, like, I can learn processes still very good, you know, and retain all of that memory, but I absolutely forget simple things. Yeah. Like, yes, like words, just things right in front of me. What is this thing called?
29:25Speaker 0Table. Camera.
29:27Speaker 1Like, you know?
29:29Speaker 1Yeah. It it also so another thing, it will it will help regenerate
29:33Speaker 1other antioxidants.
29:36Speaker 1So like your natural, like NAD levels, glutathione.
29:39Speaker 1So basically it will boost your NAD levels and
29:43Speaker 1glutathione.
29:44Speaker 1So take those and they will be,
29:47Speaker 1yes,
29:48Speaker 0hyper- Boosting glutathione. Boost it. Needed.
29:50Speaker 1Yes, everybody should be taking Glutathione.
29:53Speaker 1When I got my blood work done, my Glutathione levels were low. I was like, Dude, he's like, Yeah, that was weird, right? Yeah, that was weird. So I don't know. Yeah. That's why we get our blood work That's why you get blood work done. You have somebody like Doctor. Scott who tells you why. Deep dives into So,
30:09Speaker 1Methylene Blue again, I guess here's the concern, folks. The same thing that the concern is with Tesofensine.
30:15Speaker 1I would, and frankly,
30:16Speaker 1I would
30:18Speaker 1be reminiscent if I didn't say, Hey, don't take Methylene Blue and Tesofensine together.
30:23Speaker 1Don't do it. Okay? Also, just the same reason we don't wanna take either of those and any of those 3 antidepressants,
30:29Speaker 1especially
30:30Speaker 1SSRIs.
30:32Speaker 1K? That seems to be the serotonin sickness seems to be the biggest worry,
30:37Speaker 1not so much like a dopamine or norepinephrine
30:41Speaker 1overdose.
30:42Speaker 1You know?
30:43Speaker 1The signs of the serotonin sickness is is like kind of hypertension, anxiety, nausea, diarrhea.
30:52Speaker 1So that's what a person's gonna feel if you've accidentally taken too much serotonin.
30:56Speaker 1But, yeah, to be safe, I wouldn't take them together. This is an eitheror thing, and you for sure could and probably should cycle between them. Right? If we wanna talk about not building tolerance
31:06Speaker 1Right. Or
31:07Speaker 0Yeah. I think that'd a perfect scenario. Month on, month off. It's weird. Was thinking as we're talking, I didn't even think about that, but I have not felt the hated Tesofensine. I I haven't I can't say that I dig Bethany Blue or I hate it. I just started taking about a week. But I mean, I felt Tesofensine immediately.
31:25Speaker 1Tesofensine is pretty I think it's going to be Tesofensine
31:27Speaker 1is going to be the stronger 1 on the neurotransmitters. Yeah. In fact, like, it is a because it's up there where you with, like, the, like, appetite suppression. Yeah. It's up there.
31:37Speaker 1So looking at,
31:39Speaker 1I actually read some studies and looking at the comparison chart of, like, clinical trials between
31:45Speaker 1GLP-1s,
31:46Speaker 1so semaglutide,
31:47Speaker 1what was it? Was semaglutide
31:49Speaker 1versus Semaglutide. Tirzepatide
31:51Speaker 1versus phentermine, which is Phen Phen, which is basically it's an amphetamine stimulant to
31:58Speaker 1curb appetite.
31:59Speaker 1And
32:00Speaker 1patients
32:01Speaker 1lost
32:02Speaker 110%
32:04Speaker 1on
32:05Speaker 1Tesofensine
32:06Speaker 1and
32:07Speaker 113%
32:08Speaker 1semaglutide,
32:10Speaker 1percent on Tirzepatide.
32:11Speaker 1I think it was 3%
32:13Speaker 1of PhenFen.
32:14Speaker 0Which is kind of interesting, like, because the semaglutide
32:17Speaker 0is,
32:19Speaker 0gosh, I mean, so many people lost so much weight on it because they didn't eat at all. Yeah. So it's kind of interesting that it's only 12 or 13%. I know. Gosh, it's such a bad drug. That's the only peptide that sucks. It does suck. It does suck. I wouldn't take that, everybody. Don't take that.
32:33Speaker 1Yeah. Yeah. Because there's just so much side effects. You just feel like shit. Like, great. I mean, when it 1st came out, I'm like, okay, so you got, so there's a drug that just makes you so nauseous and sick. Yeah. And that's why you lose weight. Well, shit, I could have done that. I mean, I could have figured out something Right? Like
32:48Speaker 1There's lot of people that Trick started something maybe. You just poison yourself another way. You won't eat any food also.
32:54Speaker 0That's why they- Although it won't kill you. Semaglutide
32:58Speaker 0has wounded people to the degree that got
33:00Speaker 0so sick on it that they weren't even willing to try tirzepatide,
33:04Speaker 0let alone reticutide, which you're not even talking about the same sport. No. No, not at all. Just Not at sucks. And I like when I tell somebody about reticutide,
33:12Speaker 1it's I'd say, yes, it's in the GLP-one family, but like, let's just get that out of your brain. It's not like Semaglutide, right, because everybody has that negative connotation in their mouth. Have I ever told you about my Semaglutide experience? No. Not like I ever have. So
33:26Speaker 0it was when don't remember where, like, it was sometime this year and I was still doing a lot of the fitness content, blah, blah, blah, blah. And I wanted to throw out a 72 hour fast, which I'm great at them, but I was more in tune to work and I think it was my back was hurting, blah, blah, blah. I just needed some content. People love the 72 hour fast things. Mentally just wasn't there. I just wasn't ready to do it. And if you're not ready for a 72 hour fast, it's mental.
33:48Speaker 0And I could breeze through them usually, but my mind wasn't there. So I'm like, I'm gonna take some Semaglutide. Okay. Because it's just gonna shut my Yeah. It sucked, bro. I felt like I was gonna die. I fucking hated it. I was just like,
34:01Speaker 0Oh, I felt so bad. But you know what was cool about that experience is I got to experience it because I was never really gonna try it.
34:08Speaker 0This is, you know, this is what we've heard about it in like so many people. But it was interesting.
34:13Speaker 0It really held up to par what I hear, and it sucked. I felt like I was sick. Yes. Yeah.
34:19Speaker 0Well, don't
34:20Speaker 0take it. There's there's it's like you have a choice to drive drive a Pinto or a Lamborghini with Retatrutide as people are still driving a Pinto, and you literally can choose. Mhmm. Silly. Yeah. So for those, I guess, listening, like, I would say, you know, if the goal is
34:34Speaker 1naltrexone's
34:35Speaker 1another interesting 1 that we didn't that we just kind of glossed over. But
34:39Speaker 1people have been taking naltrexone
34:40Speaker 1in the treatment community is known to you take that if you're an opiate addict and it blocks
34:48Speaker 1your opiate receptors. But you can't get high. Cannot get high.
34:52Speaker 1I've had several treatments,
34:54Speaker 1like I've had, I won't get into like gory stories here, but right, I've had several like implants and no, I didn't get paid for them. Oh, of
35:00Speaker 0injecting that? Yeah,
35:02Speaker 1so they they take a big ass pill, and they cut you open,
35:06Speaker 1and then basically stuff
35:08Speaker 1it in you and then, yep, and then sew it back up. Similar to basically a pellet, except when they inject those pellets, the testosterone pellets. Right? They cut you off sew it in. Okay. So same thing, and it's a slow release. But the 1st time I did it, I was not ready to be done
35:23Speaker 1using drugs.
35:25Speaker 1So you wanna get high. I wanna get high. And I, can't do that. I bought every drug to try to get high, and it didn't work. In fact, it blocked it was crazy. It blocked all,
35:34Speaker 1just all of my fake happy receptors. So every drug did not work. Right?
35:40Speaker 1Yeah. Tried to do cocaine. It just felt like I was just coming down. It was like I had sort of no dos. You know? All the all the anxiety and energy and no euphoria.
35:50Speaker 1Ugh. So cut all the euphoria out, and, literally, I found, like, the only things I could do to be happy was drive fast, work out,
35:58Speaker 1have sex,
35:59Speaker 1and listen to loud music. Right? Those are the only things and I was at a point in my life where I was just
36:05Speaker 1you know, that's the only thing that mattered, just, I need happiness right now. You know? And,
36:11Speaker 1ultimately, I ended up, you know, pulling a box cutter out and and
36:15Speaker 1surgery ing me myself,
36:18Speaker 1so I could get out of me. But Things we do, man. Yeah. Drug addiction. Crazy things we do. Drug addiction. But people are using naltrexone for,
36:26Speaker 1for for appetite suppression.
36:28Speaker 1Unless appetite suppression, it's really for just no dopamine spike
36:33Speaker 1suppression.
36:34Speaker 1And if you happen to search for your dopamine spikes with food,
36:39Speaker 1that's why you take it. Boom. But
36:42Speaker 1those of you who maybe don't wanna take any of those GLP-1s, test fencing's a good start.
36:47Speaker 0Yeah, man. I mean, like you said, it's a it's been somebody I have I'm the only person that I've heard of that doesn't like it, but each is own. But here you go, man. Those are good. I think that
36:56Speaker 0we kinda dug into those good. Anything else you wanna add before we kinda
37:01Speaker 1No. Cut this off?
37:03Speaker 1I personally am not taking methylene blue because I am taking Tesofensine.
37:06Speaker 1But
37:07Speaker 1Have you ever been? You know what? We started this conversation about methylene blue of why we didn't
37:12Speaker 1originally try to pick it up. Mhmm. And because as I I did some research
37:17Speaker 1and heard some horror stories of people's, like, livers failing. And
37:25Speaker 1since then,
37:27Speaker 1I've
37:28Speaker 1read more research articles and saw thousands of people taking this and that not happening.
37:34Speaker 1So
37:35Speaker 1that could have been just bad PR or a
37:39Speaker 1fake article or whatever.
37:41Speaker 1You beloved.
37:42Speaker 1I don't know. I guess, I don't I don't even wanna say that that's a potential
37:46Speaker 1thing to happen because I don't I just don't know, folks. But that's why we had a little we that's why we we didn't do it at the beginning, but
37:54Speaker 1I know tons and tons of people who love it, take it all the time.
37:58Speaker 1And,
37:59Speaker 1I'm excited to
38:01Speaker 1I'm gonna very soon stop the Tesofensine and
38:04Speaker 1do the Methylene Blue.
38:06Speaker 0Okay. It's been a week. So, so far so good, man. So far so good. But give us some, feedback guys in regards to some other peptides. I know those 2 aren't peptides, but they're in the category of that.
38:18Speaker 0What do you want us to talk about? The next round we're gonna go obviously to the Q and A, but, we do 2 a week And, so give us some feedback on some ones you want us to dig into. We've done a lot of them, if not most.
38:30Speaker 0So we're gonna obviously circle back around for some, but, give us some feedback of what you want. Anything else before we jump ship?
38:38Speaker 1That's it. Alright. Yeah. Good weekend. Although, we will. I don't know when you watch this, but Monday.
38:43Speaker 1Okay. Have a great work week now. Take care, guys. Later.