Ep 7 · 32:25
Full transcript
Machine transcribed. Not yet read against the audio.
Research use only
Any compounds discussed may be intended for research purposes only. Nothing here is a protocol to follow — amounts, timing and cycle lengths are reported as the named speaker described them.
We are not doctors. Use at your own risk.
0:01Speaker 0my friends. Welcome back to the Peptide of the Week. I'm your host, JD Denim, and I got my co host, my buddy, Will T. Hoss. What's going on, brother? What's up, man? It's good to be back home. I've been traveling. Know that before we get started, let me just throw this out there for some certain people out there. We are not doctors. We are doing this because we
0:25Speaker 0but don't take anything to heart. We're not doctors. Seek your doctor's help. We're just going to talk about peptides for fun. Sound fair?
0:33Speaker 0So today, let's talk about the peptide of the week. We are going to talk about a growth hormone secretagogue,
0:42Speaker 0Definitely a fun 1 that we're going to be able to dig into. We will dig into some of the other growth hormone peptides.
0:48Speaker 0So Will, take it over, bro. Tell us a little about a Sermorelin. We enjoyed this 1, I know, because we've talked about it. Tell us a little bit about Sermorelin.
0:56Speaker 1So there, I guess what is important to know is there's 2 different kind of types of growth hormone peptides.
1:48Speaker 1growth hormone. That's important to talk about there. That's the good the between some of them.
2:08Speaker 1which in turn makes you hungry, and some people have a problem with that. But those GHRP
2:32Speaker 0Yeah, that's important. Let's sit on that for a 2nd because I don't think that many people know that. So let's say that 1 more time, you know, I know because some things require redundancy. Say that 1 more time. That's important.
2:44Speaker 1If you are deciding to use any of these growth hormone peptides, you should always use a GHRH
3:01Speaker 1product, when it's multiplying, right, product of the whole is greater than the sum of the individual parts.
3:20Speaker 1And some other benefits there, it's like you're gonna get a better effect than if you just did a whole lot of the GHRH.
3:28Speaker 1Okay? If you use moderate amounts of both of them, we're gonna see a much higher actual positive effect.
3:37Speaker 1you don't have to use a whole bunch of 1, and then there are side effects, there's desensitization
3:45Speaker 0Yeah, and again, I think that's why it's important that Ipamorelin in regards, in general, is ran with so many different, like the CJC test, some Marelin, because you're combining 2 different,
3:58Speaker 1right. There's, you see blends, see a lot of these growth hormone blends and you will notice that they are always a GHR agent, GHRP blended together.
4:10Speaker 0agents. Yeah, I love that because I don't hear too many people talking about that. So that's why I wanted to kind of sit on that area. So let's talk a little bit about Sermorelin and just the benefits,
4:32Speaker 0all of them. But today we're talking about Sermorelin. So let's talk about some specifics
5:14Speaker 0Because if you found it in longevity, you could take Sermorelin in particular for long periods of time.
5:58Speaker 0you advise somebody in particular, because I know I do this and I kind of advise people to do this, but
6:07Speaker 0like a Sermorelin for, let's just, you said 6 months, let's say 6 months, taking a month off and going back to Sermorelin or changing it up? Mean, there's so many growth hormone peptides.
6:18Speaker 1What about like a changing it with the Tesamorelin or something like that? What would you say? I'm curious. Yes, absolutely. I would definitely say change it up. And again, we're always talking about if you're gonna take Sermorelin, you need to be taking a GHRP also. So just FYI, when we say, we're gonna use Sermorelin, we're talking about that, and then your choice of Ipamorelin,
6:44Speaker 11st of all, like, let's just try, like, all of these supplements, everything works a little bit different in every individual's body. Some people, you know, 1 person will say, man, I loved this 1, and the other person will say, I hated it. Right? And on paper,
6:59Speaker 1it says it's doing the same thing, but everybody's body makeup is a little bit different. So a,
7:04Speaker 1you should, 1st of all, experiment with yourself so you know, hey, what works better for me? And even if you find
7:30Speaker 0That's important to a lot of people out there. So 1 of the things that, I mean, I'm not 1 of them, but 1 of the things that I do like about the FDA approval is the fact that it does mean it has been studied
7:40Speaker 0for a long time. So that's what I like about it. So if we're talking anybody's out there and having questions on growth hormone, peptides, secretagogues,
7:49Speaker 0Sermorelin would probably be the 1 you would probably want to start with just because it's been studied for so long, you can take it in longevity for long periods. So that would definitely be something that I would suggest.
8:14Speaker 1on how much growth hormone it's going to it's gonna make your body make. Which is huge if somebody's like
8:24Speaker 0taking another Ipamorelin and stuff like that. I mean, if you're taking too much, obviously you could take too much. And if your body is creating too much growth hormone,
8:35Speaker 0You know, your bones might hurt, you know, have you ever taken too much growth hormone where you're achy and stuff? Those are some of the signs that you're taking too much growth hormone, but this is a governor that will kind of block that. So that's right. Yeah,
8:48Speaker 1yes. And then I guess why, I mean, what the hell? Why do we want take, why do we want higher growth hormone in general?
9:05Speaker 1a little bit better that this than some others, but it is going to increase your sleep, especially that sleep
9:21Speaker 1And anyway, so improved sleep. Right? Promotes it'll promote fat loss, especially visceral
9:34Speaker 1repair, hypertrophy, but also like DNA repair, which in turn, you know, improves skin, skin elasticity,
9:57Speaker 0Blood vessel side, actually. So there's some studies actually. Recovery, you're gonna get a little bit more cuts in your muscle. You know, obviously, you just focused on this, but everybody wants this. It's gonna focus in on that visceral fat in your in your belly.
10:19Speaker 0So I know both you and I are big fans of actual human growth hormone synthetic, you know, like centropin or dentropin.
10:43Speaker 1human growth hormone, right, exogenous or that is the actual growth hormone. It's not 1 of these peptides that's telling your body to naturally make more of your own. I take small doses. I take 2 IUs and I take those in the morning. So I guess
11:05Speaker 1secreted in our body is actually in pulses throughout the day. Throughout the day and throughout any 24 hour period,
11:11Speaker 1our human bodies have a natural rhythm and they generally say about 4 to 7 times a day we have these growth hormone releasing pulses.
11:19Speaker 1The biggest pulse, 70 to 80% of all of our growth hormone in 24 hour period is released when we are sleeping.
11:34Speaker 1most is pre wake up from 4 a. M. To 6 a. M. We have a moderate pulse and then from 7 a. M. To 10 a. M. Mild
11:52Speaker 1why that is important. So in the morning, at night sleeping, we make the most. We make an overwhelming majority.
12:04Speaker 1when your body is making it, because then your body will say, Hey, I already have a bunch.
12:10Speaker 1I got a bunch in me. Right? Why would I make more? So you don't wanna slow your patterns down. Now when we wake up,
12:16Speaker 1right when we wake up, it's pretty low, and that's a good time to just give our body artificial growth hormone. So I take the, like, 2 IUs in the morning, but at night, the this is when these
12:37Speaker 1a meal. You wanna do them fasting, they're organ fasted. They're gonna work a whole lot better,
12:47Speaker 0Yeah, so it's funny that you say that because, you know, we've been around just gym room, the gym, gym rats and just guys like that for so long, but man, I'll tell you what, it's very common for people to think that you should be taking actual synthetic growth hormone at night.
13:19Speaker 1your natural growth hormone was very, very deficient, doctors were saying, Hey, take growth hormone
13:27Speaker 1That's what naturally we have a bunch of growth hormone. So, and at that point, they weren't worried about slowing their growth hormone down because there was not much left to slow down. So there's still a lot of literature and prescribing recommendations out from doctors
13:53Speaker 0Yeah, so like what he said to focus on that for a 2nd, you know, again, if you wanted to kind of run it in the best, like synergistic order to really maximize the growth hormone is human growth hormone in the morning, right? When you wake up,
14:33Speaker 1really, really important to take them in a fasted state. Yeah. Yep. And I would say, hey, better safe than sorry. Right?
14:51Speaker 0Did I say that right? Yeah. Yeah. Let's talk about, people in particular, this is the easy part, but people that should be taking growth hormone,
14:59Speaker 0the Sermorelin, because I know this is the focus on, who would you say that you would highly recommend it for?
15:29Speaker 1so, absolutely, a 100 they should be doing they should be doing this. We also see just muscle declining off of us as we get older.
15:41Speaker 0young kid who's 20 who wants to just get huge, right? Sorry. My next question, I was gonna actually ask you because I wanted to throw a curve ball at you. So I've had a few fathers with younger sons
15:56Speaker 0give or take, year and ask about this. So I wanna throw this to you. So a little bit of a curveball I'm gonna throw at you. Father asks you, Hey, my son is trying to play professional baseball. We want Johnny to play in the NFL.
16:09Speaker 0He is, let's just throw that out, that number 20. What is your stance on that? What would you recommend
16:25Speaker 0Sermorelin? Would you recommend that at all or would you say, Hey, listen, let's be super conservative. Your son has a lot of growth hormone in it. Let's just not do that.
16:42Speaker 1The only studies say that when your growth plates are still growing, it actually can, but the science isn't there. So do not give your little children
16:51Speaker 1this stuff. Okay? It's not gonna probably make them taller. It's gonna probably give them some weird side effects.
17:42Speaker 0a young person. Gear or anything aside, do you think so your stance is you don't think it would benefit a young 20 year old enough to the degree where you would risk it? Is that what I'm understanding? Yes.
18:01Speaker 1That will help. That will because that'll eat make them eat more. Exactly. That'll make them eat I mean, that will make them eat more. Everybody want every young kid wants to gain weight depending
18:32Speaker 0say that because that was kind of my stance because it is, it's a rough, I mean, you're talking about young, younger kids and 1, you don't want to open the doors to any type of steroids and these things can lead to that. Obviously,
18:47Speaker 0just because of the food part. It would make them hungry. If you're a young 20 year old,
18:53Speaker 0eat, you want to get big, eat a lot. You have a fast metabolism, so you should be eating. So MK-677
18:58Speaker 1will really help with that. It will help with that. I mean, yes, and some of us, it's hard. I went to
19:06Speaker 1when 2 15, 2 20, even by the next year, I was playing football starting the season at a 2 65.
19:15Speaker 1There were plenty of nights where I would eat and just eat so much that I would end up throwing up after dinner because the coaches are walking by like, eat more, get another plate, get another plate. That's funny.
19:25Speaker 1I mean, I would start seasons at 2 65 and finish them at 2 15 just because I could not. That's a lot of weight up from all the film and travel, etcetera.
19:35Speaker 12 15, I was a tight end is is a tough position to play at 215 pounds. A lot weight 2 65 to 2 15. Damn, dude. Yeah.
19:44Speaker 1But, you know, I guess I'm naturally a lean person. When I stopped playing football, I think I lost 40 pounds in the 1st
20:00Speaker 0let's talk a little bit about people that should not take it. This one's kind of an easier 1, think, just simply because
20:07Speaker 0there are some risks with human growth hormone. There are some risks with growth hormone and secretagog.
20:30Speaker 1Cancerous cells, precancerous cells, I don't know. There's there's people that say, hey, we all have cancer. We all have precancerous cells in us. But
20:38Speaker 1I don't know, guys. I would just be very conservative with it. If you have had cancer,
20:58Speaker 1is just not worth it, and I'm not going to advise anybody to do that in case it actually
21:18Speaker 0I mean, everybody thinks that because that whole thing has ran wild. But I think what Will is saying, not to put words in his mouth, but just
21:26Speaker 0be safe, man. There are so many rad peptides that if you have a family that cancer runs in your family,
21:42Speaker 0so many other peptides that will have some similar benefits, if not others that are better.
21:48Speaker 0You know what I mean? So like, just air on the fact of just being safe. That's all we're saying, man. Yeah, agree. And you're right. The risk probably isn't as much as,
22:08Speaker 1a lot of supplement companies who these Rumor mail just to compete. I don't know. Let's just say this stuff is just terrible for people. And we'll send you shouldn't be taking it, we'll sell more. But
22:19Speaker 1I wouldn't risk it. I mean, that's me personally. People can do whatever they want to do, but there's a lot of
22:25Speaker 0other effects. Taking growth hormone. I mean, I'd heard that too. It's going to lead to cancer, blah blah blah. But anything that I do, I kind of study and I look into it and
22:34Speaker 0there's really not that much out there that says that it's going to lead to cancer. Now, if you're taking 8 to 10 IUs a day, if you're taking anything abusively,
22:47Speaker 0using something for the benefit, like literally to get the benefit and that's it, like conservatively,
22:58Speaker 0the truth. Just the truth. It's got a bad rap. Growth hormone has a bad rap. We would on the side of being conservative if cancer runs in your family. And by all means, if you have had cancer, don't take it. Why risk it?
23:10Speaker 0But for the normal, you know, Joe Brown, you know, we both take them. We both take growth hormone and we both take these, pedagogues
23:19Speaker 0because they work well. And for guys like us that like to lift weights, they help prepare your muscles, man. Especially,
23:26Speaker 0you know, we both played ball, we both have been lifting heavy weights for a long time, so we take these for a reason because they work.
23:41Speaker 1somebody is hugely buff or cut up because they're taking HGH. Like, guys, it is not. Regular
23:47Speaker 1HGH. The security guys, they're they're they're they're not as amazing also as people as people think, and they sure as hell don't work fast.
24:08Speaker 1yeah, the threshold. I wouldn't even start. I wouldn't even I mean, we talked about this earlier. Right? Like, I wouldn't even don't even waste your money. If you're gonna buy 1 bottle
24:22Speaker 0Yeah, so let's talk about that because I don't think we've talked about that on here. That's important, dude. Let's sit on that. For anybody listening, any type of peptide company you wanna use, doesn't matter.
24:34Speaker 0don't do it. It's not going to do anything. Like if that's, you're going to play for 3 weeks or 1 month, it's just really just save that money, man. These peptides are good. They work great.
24:43Speaker 0Unless you're talking about GLP-one or something like that, most peptides need to be ran for months, months, plural, where like, you're really gonna get the benefits over time, you know? So,
24:54Speaker 0you know, if that, we're just being honest with you, you know, if you get a 1 bottle of BPC-157:5mg,
25:01Speaker 0that's not even a full cycle of what it's, so just don't do it. Like, you know, it's not worth the money. So these things are, peptides
25:09Speaker 0are so amazing, but you need to run them for months, just to be blunt. You need to run them for months. So unless you're in it to really get the true benefits,
25:18Speaker 0that's what I would say and get advice I would give anybody if you're doing it for a while. Yep. And especially the secretive drugs.
25:30Speaker 1Don't make a decision if something works or doesn't work in any shorter amount of time for that. And budget for it, plan for it, and
25:51Speaker 0Don't even mess I mean, and that's part of the reason why we're doing this. We love peptides and we're still growing and learning ourselves, but that's the key is we are still growing and learning and we don't stop. We continue to read and read and read and try and try and try. And we work with a lot of people that try different things. So that's how we know, you know, and you're not gonna know unless you try it, you know? That's just the best way. You can read all about it, that's good to start there.
26:20Speaker 0But everybody's body is a science project, man. Just because it works, Tesamorelin works great for me, you might hate it. You know what I mean? So you're not gonna know until you try it. Yep, absolutely.
26:33Speaker 0these are chains of amino acids, man. You don't need to worry about them much. There's not a whole list of risks, a little bit here and there, I guess, but not really.
26:55Speaker 0growth hormone peptide for a few months, you will see a difference. You will. You'll feel different. So- Yep. And right. Peptides are just our
27:26Speaker 1slowing down its production of that same hormone or etcetera. Right? These are just signaling your body to do something normal.
27:47Speaker 0love when I read through certain comments when I talk about different peptides and there's certain people that yell and scream,
28:12Speaker 1and expect it to make you healthy immediately just just from that. Right? We also have some lifestyle factors that we need to increase. Oh, yeah. Which brings us to another point. So
28:33Speaker 1releases our natural growth hormone. Any type of stress, and I mean positive stress like exercise,
28:44Speaker 1Even every time that you are hungry, right, guess what, our body is starting to make more growth hormone,
29:06Speaker 1and that makes us produce more growth hormone. So this peptide, all they've figured out is if we could just signal the ghrelin receptor to wake up a little bit,
29:22Speaker 0We didn't talk much about that, but fasting. So anybody, obviously, I'll talk about fasting part because I'd fast so much, but I love it, man. I mean, why does fasting work so well, especially longer fasts, 24 hours plus?
29:34Speaker 0You know, your body is really shooting up an exorbitant amount of human growth hormone, man. A lot of people think that you lose a lot of muscle. You don't, you're really shooting up that human growth hormone in your body.
30:17Speaker 1for 3 to 6 months, take 1 month off and repeat. The only reason you're taking that month off is again so we just don't build
30:26Speaker 1It it'll it'll stop being as effective over a long period of time. The whole point is to just give your body a little reset.
30:35Speaker 1What that looks like is most most Sermorelin you're gonna find is in 5 or 10 mg bottles.
31:20Speaker 0Good stuff, man. We can talk about these security dogs forever, man. Next time we'll probably do it. We'll pick another 1, but
31:32Speaker 0Will and I both take HGH in the morning and we take 1 of these at night. I personally switch it around every few months, CJC
31:43Speaker 0and I switch it, you know, every few months, but I'm always taking HGH in the morning and secretagog at night, and it's really- And he's talking
32:14Speaker 0Right on, my brother. Well, this is a good 1, man. Well, we appreciate you guys. We will be seeing you next week.