Selank

Selank is a synthetic peptide based on tuftsin, developed in Russia and used clinically there for anxiety. Research has examined effects on anxiety and on the balance of neurotransmitter and immune signalling, with interest centring on whether an anxiolytic effect can be achieved without sedation or dependence.

As with the other compounds from this research tradition, the literature is largely Russian-language and has not been substantially replicated by independent groups. It is registered as a medicine in Russia and is not approved elsewhere.

Anxiety, stress response, and effects on BDNF and neurotransmitter signalling, from a literature concentrated in one research tradition.

The originating literature reports it as well tolerated without the sedation or dependence associated with benzodiazepines. That record has not been independently verified.

Supplied as a nasal solution in its registered form, and as a lyophilised powder elsewhere.