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Ep 1121h 8m · 13 July 2026 · Learn

Peptide of the Week: Gear, GH, Blood Work & Real Talk With Josh Holyfield

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Ep 112
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Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Josh Holyfield fitness coach, educator, and one of the most straightforward voices in the peptide and optimization space. This one gets into blood work patterns, the real problems with Western medicine, gear cycles, HGH science, and why most men are failing before they even start.

Chapters

00:00 – Meet Josh Holyfield

01:16 – From Fitness Coaching to Peptide Education

06:29 – Why He Walked Away from High-Ticket Coaching

10:04 – Why Traditional Medicine Falls Short

15:36 – The FDA, Pharma & the Future of Peptides

20:49 – Blood Work Every Man Should Understand

24:25 – Low Testosterone: Fix the Foundation First

28:23 – Helping Men Transform Their Lives

34:27 – Favorite Anabolics & Building Muscle

37:19 – Growth Hormone, IGF-1 & Recovery

45:10 – Optimizing Steroid Cycles Safely

55:11 – Enhanced Games, Sports & Final Thoughts

We cover:

🩺 What Josh actually sees on blood work

– Most men are walking around with total testosterone between 300–500 and most doctors think that's fine

– Low T is often a sleep and diet problem first not a TRT problem

– Elevated LDL on keto or RETA is expected your doctor doesn't know that

– APOB + HSCRP are better predictors of cardiovascular risk than LDL alone — and most doctors don't test for them

– Statins remove cholesterol the raw material your testicles use to make testosterone. Doctors prescribing statins to low T men are making the problem worse

– Women are almost universally under-eating this is the #1 issue Josh sees

🏥 Why Western medicine is failing

– Doctors aren't malicious they're programmed, incentivized, and legally constrained

– FDA is funded by the pharmaceutical companies it regulates

– Insurance companies dictate treatment guidelines not patient outcomes

– A drug that cures at 79% for $5 can't go to market if a 95% drug exists at $10,000 that's the law

– Peptide regulation is coming but so is more freedom for doctors to prescribe them

💉 HGH — the science behind timing

– GH converts to IGF-1 in the liver that's what builds muscle

– Insulin and IGF-1 compete take GH fasted so it can do fat burning and repair FIRST

– Morning dosing: just came off an 8-hour fast, pituitary still gets its natural 2–3AM pulse

– Night dosing: shuts down your natural pulse for ~18 hours you lose the freebie

– On GLP-1s: morning GH is even more important since RETA keeps insulin elevated for days

– Josh's dose: 6 IU before bed, fasted spectacular results

⚗️ Favorite Compounds — Round Table

– Josh: Testosterone cypionate daily (long ester), Masteron E, micro-dose Tren, EQ for aromatizers. Never needed an AI even at 600mg test/week

– JD: Low test base, Winstrol to kick start, Masteron, occasional Primo. AOD, 5-Amino-1MQ, Testofensine, HGH 2 IU

– Will: Sustanon 3x/week, Masteron, Winstrol, Cardarine for athletic performance. HCG 1500 IU + HMG for fertility prep. Low dose RETA twice/week for brain function

🧠 Real talk on gear

– More gear is not always better diminishing returns are real above 800mg test

– Anavar is a starter drug because people are scared Winstrol actually does more

– If you don't know the difference between esters, you're not ready

📺 Subscribe for more no-fluff peptide education every week.

Follow us on social media:

JD's Instagram: https://www.instagram.com/jddenhamofficial/

Will's Instagram: https://www.instagram.com/williamthaas/

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Follow Josh Holyfield:

Instagram: https://www.instagram.com/josh.holyfield/

YouTube: https://www.youtube.com/@josh_holyfield

Join The Community: https://www.skool.com/peptideoftheweekcommunity

Research use only

Any compounds discussed may be intended for research purposes only. Nothing here is a protocol to follow — amounts, timing and cycle lengths are reported as the named speaker described them.

We are not doctors. Use at your own risk.

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