Epitalon

Longevity

A synthetic tetrapeptide developed from research on pineal extracts, studied in relation to telomerase activity and circadian regulation.

Research use only

Any compounds discussed may be intended for research purposes only. Nothing here is a protocol to follow — amounts, timing and cycle lengths are reported as the named speaker described them.

We are not doctors. Use at your own risk.

What it is

Overview

Epitalon is a synthetic four-amino-acid peptide that emerged from Soviet and later Russian research on pineal gland extracts and ageing.

Almost all of the primary literature comes from a single research tradition, much of it published in Russian and not replicated by independent groups. Reported findings include effects on telomerase activity and on markers associated with ageing in animal models. The concentration of the evidence in one institutional source, without independent replication, is the central caveat and should be read as limiting every claim made for it.

The evidence base

What the research examines

Telomerase activity, circadian and pineal regulation, and longevity markers in animal models, from a literature that is largely un-replicated outside its originating group.

As reported on the show

Reported protocols

Attributed to the person who described them. Amounts, timing and interactions as stated on air.

No protocol reported

Nobody has described a protocol for Epitalon on the show. When someone does, it will appear here attributed to them.

Reported in the literature

Adverse effects

No independent human safety literature is available. The originating research does not report serious toxicity, but that record has not been independently verified.

As supplied