Peptide Q&A #30 – Fasted vs Fed HGH, Tesamorelin Storage Myths, Retatrutide Fat-Loss Protocol Peptide of the Week https://peptideoftheweekpod.com/episodes/peptide-q-a-30-fasted-vs-fed-hgh-tesamorelin-storage-myths-retatrutide-fat-loss-/transcript We are not doctors. The content on this site is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Amounts, timing and cycle lengths below are reported as the named speaker described them. Nothing here is a protocol to follow. --- 0:01 Speaker 0: Late night bites with friends, 0:03 Speaker 0: already hard to beat. 0:05 Speaker 0: That 1st too hot bite of fries you couldn't wait for, 0:08 Speaker 0: followed by ice cold Pepsi. 0:11 Speaker 0: Now that hits different. Suddenly, 0:13 Speaker 0: the energy kicks back in, the night goes longer, and the laughs don't stop because Pepsi brings out more flavor, more fun, and more of the moment. Food deserves Pepsi. Grab a Pepsi 0 Sugar today. 0:36 Speaker 1: Welcome 0:37 Speaker 2: back to the Peptide of the Week podcast. I'm your host, JD Denham across the way, my buddy William T. Haws. 0:43 Speaker 1: What's up, dude? What up, man? 0:45 Speaker 2: Not much. How's life? What's going on? It's good. I got a little tattoo on Friday. Was that Friday? No, Saturday. Yeah, it was Saturday and I got, think a Wednesday. Feeling pretty good. 0:54 Speaker 1: Went, Jake goes very deep. Really? I mean, I got my whole kneecap done and I could fall asleep the whole time. 1:02 Speaker 1: We only went Did back that stuff work? 1:05 Speaker 1: Yeah. It? Yeah. Wonder why it didn't work for me. Did you wrap it with a yeah, Yeah, you did. That's the key. That's the key. So all we did, I mean, you barely see, because like we didn't do a whole bunch. 1:15 Speaker 1: True, 1:16 Speaker 1: pain, 1:17 Speaker 1: dude, the older I get, the more tattoos 1:19 Speaker 1: hurt. I don't care who you are. Like if you're saying that tattoos don't hurt, Yeah. You're lying and trying to be tough. Yeah. Although girl you know what? It's funny. Girls girls, women, women have a higher pain threshold tolerance than we do. Right? Because they have to have they have to have more bear babies, and that shit hurts. 1:38 Speaker 1: But it hurts. 1:40 Speaker 1: That thing hurts. The older I get, it hurts. Yeah. Lead is same thing. More of a pain pussy I get. So, yes, I've used some I used some numbing cream on there. 1:48 Speaker 1: And for the reference, everybody, like, we have some really good 1:51 Speaker 1: numbing cream that's like, it's really good. But I also have always done, like, put it on, sometimes not put saran wrap around it. Right. And then sometimes have, it's funny, on the way there, I was chat GPTing like, much of an effect does is it to actually Saran wrap the thing? And they basically said, well, this is a clinical, like standard practice. I forget the name of it, but to wrap something in a non breathable deal and it makes about a 60% difference. That's a big deal. That's a huge deal. I've noticed that because I've done it numerous times. As you said, when you get older, I don't think that you're, 2:26 Speaker 2: I just think you get sick of pain. I'm covered in tattoos. I've had so many and like, I'm like, I don't remember like a few tattoos back and I've gotten numerous since I've said this, but I was like, I'm done. Like I'm done. I'm pained out of tattoos. I did for quite a while, 2:41 Speaker 1: but anyways, like I'd have no problem saying that I use that tattoo cream. I don't care. Don't care. Whatever. Don't care anymore. No. Now folks, everybody's listening. Like if it's your 1st tattoo, no, you cannot use numbing cream. Like we went a long, long time. We got to know it's not allowed. You have to earn it. 2:56 Speaker 1: You also cannot 2:58 Speaker 1: tattoo yourselves for the 1st time, 3:01 Speaker 1: sleeves down 3:02 Speaker 2: and knees down. Not allowed and neck up. Right? Pulling their hands 1st. Yeah. 3:09 Speaker 1: Don't stand on your hands. Yeah, you can't do that. You have to earn your way. You have to earn your way there and earn your way getting tattooed and dealing with a lot of pain. But I do remember after I got my chest done, 3:19 Speaker 2: I also said, dude, I'm fucking done. And I don't, and I took a good break. Yeah, me too. Maybe like 6 months. I'm like, dude, that shit hurts. And then you though, then you get another 1 and you're like, Oh man, I did my left hand and I couldn't always get my right hand. I like your right hand 1. Yeah, he did, he did good. He went really deep. He even told me, he's like, I had to go really deep on your right. So I was expecting him to scar up and none. 3:41 Speaker 1: Apparently we have 6 scabbed over. If you've been doing HGH, you have, you 3:46 Speaker 2: know, it's funny you said that. So I was thinking about it, I'm like, how did I not scab at all 3:51 Speaker 2: and peel off, which is very, I think it's 1 of my 1st it's never done that. Would imagine this peptides. Yeah, probably. Only difference. Probably. Taking a lot. 3:59 Speaker 1: Probably. 4:00 Speaker 1: I mean, I even put the serum, the SNAP-eight and GHK-3Cu 4:03 Speaker 1: serum on mine. So did I? Thinking like, maybe 4:07 Speaker 2: you're like in a really open wound that might not be the best idea, but I do do that. He said that. He said put it on it and I'm like, you sure it's not gonna take out the ink? He said, No, I think it'd be good. So I was roaming in at night, so obviously that was it. 4:20 Speaker 2: Good. Hip heads are awesome. Well, today is a Q and A episode, 4:24 Speaker 2: which we all love so much. Good questions. Good questions. 4:28 Speaker 2: Yeah, we'll jump right in because this usually goes about an hour or so. Yeah. We'll jump right in. You always do the honors. 4:35 Speaker 1: Okay, number 1. So everywhere I look online, it says that for exogenous 4:41 Speaker 1: HGH to work, that means like the actual HGH 4:44 Speaker 1: hormone 4:45 Speaker 1: somatropin that you're injecting. Okay. 4:48 Speaker 1: Exogenous 4:48 Speaker 1: means exit outside 4:50 Speaker 1: of the body going in. Endogenous means internally made. 4:56 Speaker 1: Exogenous is to work at its most optimal. You have to take it fasted, but I've taken HGH fasted and with meals, and I've got amazing results both times. Only difference I felt is that when I take HGH fasted, it gives me more of a fat burning effect. When I take it with food, it gives me more of a performance recovery effect. Is this something I made up in my head or does HGH only really work when take it 5:18 Speaker 1: Love the podcast. Keep up the word good work guys. 5:21 Speaker 1: Okay. I think that holy shit. Are incredibly in tune to your body. I was wondering 5:27 Speaker 1: if you felt that or read that. He 5:30 Speaker 1: read the opposite That it shouldn't really work. It should blunt the effects, but this is what I feel. Right? I mean, that's really amazing. You are in tune with your body like crazy because that is basically, that is what's happening. That's true. 5:43 Speaker 1: The, 5:45 Speaker 1: the insulin, 5:46 Speaker 1: basically if you eat, if you are not fasted and you are fed before taking the HGH, 5:51 Speaker 1: it is going to blunt the metabolic effect. 5:54 Speaker 1: It's going to blunt the fat burning effect. Okay? But regardless 5:58 Speaker 1: if you have food in you or not, when you take the HGH, it's always going to convert to the IGF 1 and IGF-one is what gives you that recovery effect. 6:07 Speaker 1: Okay. 6:08 Speaker 1: So 6:09 Speaker 1: you're feeling everything you just said is perfectly true. 6:12 Speaker 1: Although, so, so if fasted, 6:15 Speaker 1: you're getting both effects. Okay. Metabolic and IGF-one, 6:19 Speaker 1: which is the growth recovery, 6:21 Speaker 1: just as much. If not fasted, 6:23 Speaker 1: you're getting a blunted metabolic, therefore fat burning effect and the same good IGF-one output. Yeah, still getting the IGF-one. 6:31 Speaker 2: I don't know why you would not want to get both, like the fat burning. I mean, that's 1 of the reasons why I love HGH so much because of fat burning, man, you're taking it for 6 months plus you are cruising. You really do notice the fat burning, but 6:44 Speaker 2: I've also read that bodybuilders will take it with, you know, food and when they eat with a lot of like, 6:52 Speaker 2: glucose, 6:53 Speaker 2: you know, big meals. 6:56 Speaker 2: I don't think it's going to change the difference in regards to IGF-one. It's just going to change the fat burning. So if you're going to do it, why not burn fat? 7:02 Speaker 1: Yeah. 7:04 Speaker 1: Why not? Might as well. Even if you're big, it's still good to burn fat. So, but that was a great question. I've, it's never crossed our path. So I thought that was really he's right. Like when I 1st started doing growth a few years back, like I didn't even think about, never had heard about this fast, fasted or not several 7:19 Speaker 1: years ago. And, 7:20 Speaker 1: and it sure still worked. 7:22 Speaker 1: Now, I guess I'm not as in tune to hear going, Oh, it worked better. You're eating without not fast food. Yeah. Okay. Still works. Yeah. I 7:30 Speaker 2: mean, it's, I think that, you know, we've gone over, there's going to be some that aren't as important to do that, that you need to be fasted, like the healing peptides, blah, blah, 7:40 Speaker 2: But you know, peptides are not cheap. So if you're going to do them, do them well, you know, and you want to get the best for your buck. So again, if you're going to get the same effects with IGF-one, 7:51 Speaker 2: might as well do it faster dude and get the fat burning. Like again, who doesn't want to burn fat? 7:56 Speaker 2: You know I mean? Big bodybuilders burn fat. 8:00 Speaker 2: All right, but good question, man. That was a great 1. 44 year old female, 150 8:05 Speaker 2: pounds, five'nine athlete 8:07 Speaker 2: and gym girl 8:08 Speaker 2: in weights section, not cardio equipment. If you know what I mean, I eat protein, 130, 150, 8:15 Speaker 2: higher fat, moderate, low carb, 8:17 Speaker 2: had a baby at 42, good for you and still feeling not quite myself yet. 8:23 Speaker 2: I'm trying to figure out when did she have the baby, but anyways, looking to add muscle like bikini model build, 8:29 Speaker 2: have a great tone now, just a few squishy areas I want to firm up. So I'm 8:34 Speaker 2: close, just need some help. My current stack is Tessa, 8:38 Speaker 2: 1.5 8:39 Speaker 2: mg nightly, Reta 8:41 Speaker 2: micro dosing 1.5 mg weekly, 8:44 Speaker 2: GHKCU 8:45 Speaker 2: 2.5 mg and the GHKCU 8:48 Speaker 2: serum. Wolverine stack, Wolverine blend 1.5 to 2.5 mg, 8:53 Speaker 2: 3 to 4 times at night, 8:55 Speaker 2: 3 to 4 4 night, 8:57 Speaker 2: bought HGH, 8:59 Speaker 2: 20 vials, 9:00 Speaker 2: Tessa Ipah, and CJC Ipah. 9:03 Speaker 2: What should I do? Change my current dose, 9:07 Speaker 2: add HGH 9:09 Speaker 2: or switch to Tessa Ipamorelin. 9:11 Speaker 2: I tried CJC Ipamorelin. Wasn't as big a fan of it. Got the rash. Thanks for all you do. Love your products. Podcasts, 9:19 Speaker 2: the GHK-3Cu 9:20 Speaker 2: serum is awesome from my face. I'm Want to start there? Yeah, go ahead. Cause you have a little bit personal experience as part of that. I've been kind of ready 9:29 Speaker 2: for this to pop up because I knew it would. 9:32 Speaker 2: Man, so 9:33 Speaker 2: for the longest time I didn't run CJC just because I'd read if there was just, there's some of these secretive cogs, I run HGH and, just some of the negatives I've 9:43 Speaker 2: with the CJC. I just never had the huge interest 9:47 Speaker 2: in running it. And, I think I've talked about it on the podcast, but I did, I did it a few, maybe a month ago, 2 months ago, whatever it was. 9:55 Speaker 2: And I did good for about a week and then I injected it and I got an instant rash. I mean, it was it was so trippy that like it was so freaking instant that I was like, Woah. 10:05 Speaker 2: And I do it in my legs sometimes and it was like, rash. 10:09 Speaker 2: And I felt a little bit weird and I'm like, That was gnarly. 10:13 Speaker 2: So needless to say, I didn't do CJC anymore because 10:16 Speaker 2: for those that don't know, if you do it and you have that, it's probably going to be worse next time. Not every time, generally speaking. Yeah, 10:23 Speaker 2: generally. It's a histamine situation. 10:26 Speaker 2: So KPV does work. KPV is great. 10:30 Speaker 2: So to finish this off, 10:32 Speaker 2: my wife, you know, she's tiny and, we switched things around and she loves testing around blah, blah, blah. So I was going to try the CJC. I didn't think that she would have a reaction. I think it's not so common that I was that worried about it, to be honest with you. And I injected her just 10:50 Speaker 2: 10 units and, dude, she went to put my son to bed almost 10:55 Speaker 2: immediately. And she came out and her lips 10:57 Speaker 2: were so freaking swollen 10:59 Speaker 2: and she was completely red and she had this fear in her eyes. I think something's wrong. And I was like, Holy shit, woah. 11:06 Speaker 2: You know, that's my wife. I'm like, Woah, woah, woah, woah. And like, I'm like, Wow. So I had KPV. I gave her a shot at KPV that helped, 11:13 Speaker 2: but it was gnarly dude. I called Will. Was like, dude, bro, holy woah. 11:18 Speaker 2: So I won't really be doing CJC anymore. 11:22 Speaker 2: Mean, people love it. People love it. That's great. But then I think, I mean, you had the same thing. You had the rash. It seems to be way more common than even I was even expecting it to be. I mean, for me to get it and my wife to get it different bottle, wasn't the same bottle, widely 11:37 Speaker 2: separated from in regards to a couple of months or something from when we did it. 11:42 Speaker 2: Hey, anyways, I read negatives. There was a reason I didn't do it for a long time and, yeah. 11:48 Speaker 2: So there you go. Everybody, 11:50 Speaker 2: Tesamorelin, Ipamorelin wins in regards to the question there. 11:55 Speaker 2: Should you do the HGH now 11:57 Speaker 2: for women, my take on this might be different than Will, so let's dig into it. For women, a little bit goes a long way. 12:05 Speaker 2: Doing an 12:07 Speaker 2: HGH in the morning and the secretagogue at night, I'm going to tell you, I think that's going to be a little bit much for a woman. I just don't think women need that much. I would do either or. And I'm going to lean towards the HGH because it's actual, some somatropin in the morning. And I mean, a woman could get away, in my opinion, with 1 IU. I mean, I do too. You know, 1 IU would go a long way. 12:29 Speaker 2: So I would try that. You have it. So you bought it. So why don't you do that and kind of put the secretagogues on ice? Now you could do the Tessa Ip at night. Again, I think it's overkill for a woman. If you're a man, I think that would be great. I just think it's too much for a woman. 12:47 Speaker 2: Yeah, so that's what it meant. I would kick the CJC to the curb, man. I am not a fan and I would hate to see what happened to my wife happened to you. It sucked. It was scary. 12:56 Speaker 2: She was scared. 12:58 Speaker 1: That's where we're at. Yeah, that's scary. And it's going to get worse. Like it wouldn't. So basically Her lips were huge. 13:03 Speaker 2: Huge. I mean like huge. And she was flushed. She pulled up a shirt and she was just freaking fiery red. I was like, woah dude, that I was getting that. So if you do have that, so you all know, 13:15 Speaker 2: have some KPV that is an antihistamine. So 13:18 Speaker 1: like, and KPV, 13:20 Speaker 1: but like also 13:21 Speaker 1: an antihistamine, 13:23 Speaker 1: which we all know Benadryl 13:25 Speaker 1: stuff, stuff like that will also help. But if all you got is KPV, 13:29 Speaker 1: use the damn KPV. And 13:32 Speaker 1: it would generally like every single, every allergic histamine related reaction we have, it always gets worse every time. So 13:39 Speaker 1: you probably cannot, I would throw that away or find somebody who wants to use it. But you used it. So find a close friend. 13:47 Speaker 1: They're to get us there, Betty. So I do think that also we have talked about this before, but the quick lesson on 13:54 Speaker 1: running the secretagogues 13:56 Speaker 1: with HGH, 13:57 Speaker 1: with exogenous HGH, right? Basically the 14:01 Speaker 1: Tesamorelin, 14:02 Speaker 1: the actual, it activating your pituitary pituitary telling body to, Hey, let's make more HGH 14:08 Speaker 1: will 14:09 Speaker 1: get blunted. 14:11 Speaker 1: Okay. By, if you're taking exogenous HGH and you already have high levels, 14:16 Speaker 1: then that pituitary action might get blunted a little bit. And that new, the secretagog 14:21 Speaker 1: just may not do much for you. It may not really stimulate any more growth. 14:27 Speaker 1: The Ipamorelin 14:28 Speaker 1: portion of it will absolutely still enhance your growth pulses. 14:33 Speaker 1: So even when taking exogenous HGH, 14:36 Speaker 1: the IpA will still kind of enhance our regular pulses. Your body just won't be making more from the secretagog. It might be, but maybe it's negligible. 14:44 Speaker 1: But Tesamorelin has another property besides just 14:48 Speaker 1: telling pituitary to make more growth, and that is to target belly fat. True. And and 14:56 Speaker 1: what's our other adip what's our other kind of fat that's stuck to your internal organs that's really bad? 15:01 Speaker 1: Forgive 15:02 Speaker 1: visceral. Thank you for that. Thank you for the crowd. 15:06 Speaker 1: Tesamorelin will do that will also burn that. Okay? And that that effect will not be blunted. So 15:12 Speaker 1: but like JD said, I still think, like, the real deal, right, They're all HGH is probably best. And 1 I use probably all you need. What I would suggest 15:20 Speaker 1: instead of stacking even more growth hormone, 15:23 Speaker 1: know, producing, 15:26 Speaker 1: compounds on there, I would maybe take IGF-1LR3, 15:31 Speaker 1: which is not really a, it's, it's the byproduct, right? It's, it's basically the portion of when you do HGH, 15:37 Speaker 1: it basically makes your body metabolic or recovery, right? Recovery, meaning build more, build tissue and build muscles back. IGF-one is 15:46 Speaker 1: the end product of that that builds tissue. So it's probably your best muscle building. 15:51 Speaker 1: Compound, you don't really wanna do it for very long, but IGF-1LR-three 15:55 Speaker 1: might be a good thing. And, and it takes time. Like your body, a bikini body 15:59 Speaker 1: is doable at your age, 16:02 Speaker 1: but 16:03 Speaker 1: things just take time and consistency, consistency, 16:06 Speaker 1: and, and, 16:07 Speaker 1: you know, get a plan that is sustainable that you can keep long term, right? And long term by a year. 16:13 Speaker 1: And that's what I mean. I don't mean 20 years, but that's kind of how you'll slowly whittle away those squishy spots and turn them hard. Right? There's nothing for a woman 16:23 Speaker 1: where there's nothing really we can give you that whack overnight like steroids would do for a man. Yeah. 16:29 Speaker 1: They would do that for a man. You took enough stuff and you ate- Retta's 16:33 Speaker 2: close. But you're doing that. She could up the Retta too. We don't know what she's trying to weigh. She doesn't talk about her weight, but 1.5 is pretty low. I mean, assuming a microdose on Monday, Wednesday, Friday, 16:43 Speaker 2: probably 0.25 16:45 Speaker 2: of a mg. You could go up to a mg and just see if that helps. That would help a little bit, I think. True. 16:51 Speaker 1: True. That is true. I'm fairly low. Yeah. It's 1 burn fat. That's very low. So 1.5 mg a week. That's very low on Loretta. 17:00 Speaker 1: Feel free to go up a little bit. No. Alright. I'm reading. Number 3. 17:07 Speaker 1: Any idea if you will discuss 17:10 Speaker 1: Prostamax 17:11 Speaker 1: and 17:12 Speaker 1: the salute? 17:14 Speaker 1: I'm 49 and have an OAB overactive bladder. I've ordered 17:18 Speaker 1: both and waiting for delivery, but wanted to see what the experts have to say. I love the show. 17:25 Speaker 1: Do you I don't really like okay. Maybe 17:29 Speaker 1: maybe once we get a little bit more data and maybe, and have tried it and have, have some more experience, 17:35 Speaker 1: I think that we could do an episode on that, but now is not the time, but 17:41 Speaker 1: we will look into it. 17:43 Speaker 2: Yeah. It's not something that's really like, like something that's really, really crossed our path. I, you know, I'm 48, so I'll tell you my experience of that. I don't really run into that right now. I did during COVID, 17:54 Speaker 2: so maybe 20 20 give or take. I was like peeing like 6 times a night. It was horrible. And, I was just thinking there was something wrong with me. Finally, my wife said, you got to see a doctor. And at that time you couldn't see a doctor. So I had to wait. So I finally got on a zoom call with a doctor and 18:10 Speaker 2: I thought he was going to have some earth shattering 18:13 Speaker 2: advice 18:14 Speaker 2: because I was peeing 6 and 7 times a night and not sleeping well. Yeah. And, 18:19 Speaker 2: his advice was this, he said, How old are you? And I, you know, at the time, 44 or whatever it was. And he goes, and I said, and I'm a testosterone, you know, put it on the line. He goes, you're just getting old man. And that's really kind of where he left it. I said, I was kind of expecting a little bit more doc, 18:36 Speaker 2: but just more proof on why I'm not a huge fan of Western medicine. But my 18:41 Speaker 2: point on that story is I 18:44 Speaker 2: never really did a whole lot to fix it. I don't know what really rectified it. Don't run, I don't have that problem anymore. 18:50 Speaker 2: But I'm going to always on the side of, you know, Vesalud is a bioregulator, so it's not, you know, it's, it's, I think Prostomax, 18:59 Speaker 2: I think that's like an over counter. I don't know much about that, but that's a bioregular. I'm going to always on the side of trying that before a pharmaceutical. 19:07 Speaker 2: I just, pharmaceutical 19:08 Speaker 2: suck. I just am not a fan of them. I didn't take whatever that doctor prescribed me just because I'm not a fan of pharmaceuticals. 19:16 Speaker 2: And I got past it. So, 19:18 Speaker 2: again, I don't remember how, why and how it fixed itself, but I don't have the problem anymore. So 19:23 Speaker 1: I don't know. That's kind of vague, but-0.23: No, that's fine. I don't really have a great answer either for you, but I would say, so is there anything that you are taking 19:30 Speaker 1: that might 19:31 Speaker 1: swell your prostate? 19:34 Speaker 1: Okay. Are you taking any steroids? 19:36 Speaker 1: Like, are you taking testosterone? Are you taking 19:39 Speaker 1: Winstrel or, 19:41 Speaker 1: Masderon or, 19:42 Speaker 1: Primo? 19:43 Speaker 1: If I take Primo for like 2 weeks, 19:47 Speaker 1: it will like swell up my prostate every time. Interesting. Yeah. 19:51 Speaker 1: And are you just peeing a lot or do you have like a weak stream? 19:56 Speaker 1: Basically you gotta pee really bad. And then you're gonna pee and like, 19:59 Speaker 1: it just kind of, I mean, it comes out, but like not nearly equal 20:03 Speaker 1: to what you 20:04 Speaker 1: had to do. And then you feel it and then you're like, well, I guess I'm done. 20:07 Speaker 1: So 30 minutes later, you gotta go pee really bad and the same thing happens. Yeah. 20:12 Speaker 1: That is generally a swollen prostate and obviously, and it occurs from those substances because of DHT, right? Those are all DHT derivative compounds, and therefore they're going to raise the hell out of your DHT 20:25 Speaker 1: And do fast, right, finesse 20:28 Speaker 0: The perfect lunch combo. 20:31 Speaker 0: That 1st bite of your favorite sub, followed by ice cold Pepsi. Add a couple of friends, and now that's next level. Suddenly, the laughs get louder, the stories keep flowing, and the food tastes better because Pepsi brings out more flavor, more fun, and more of the moment. Food deserves Pepsi. Grab a Pepsi 0 Sugar today. 20:51 Speaker 1: Thread are the, like, 20:54 Speaker 1: pharmaceutical 20:55 Speaker 1: drugs that Brutal. That will fix those. But side effects on those things suck. Horrible. It's the same thing that they we talked about, like, for me taking, 21:05 Speaker 1: to combat 21:07 Speaker 1: hair loss. 21:09 Speaker 2: So sex drive sex drive, 21:12 Speaker 1: like I really feel those things. I disliked 21:15 Speaker 1: them, but the good thing is whenever I, in the past, if I have felt to that, I take literally 1 pill for 1 day, 2 days, and it fixes the problem for a year or until I'm dummy again, try to do like pretty much, 21:28 Speaker 1: but it fixes them immediately. I did the 1st time I ever took them, you know, I took it for like a week straight and like, yeah, killed this, killed my sex drive, but also just made it like, 21:38 Speaker 1: it made me almost just depressed. 21:41 Speaker 1: Like brain's like, don't 21:43 Speaker 1: care about much, you know, no happiness, 21:46 Speaker 1: no motivation. 21:49 Speaker 1: Sucks. Nobody wants to feel like that. Nope. Unless you're making yourself rather P 6 times the week, the same night than feel like that. So I don't know. I'd look into it. 21:58 Speaker 1: Sometimes it's just an estrogen hormonal imbalance, 22:02 Speaker 1: but I would 22:03 Speaker 1: I'll guess with JD too, like, man, you ordered them, take them. 22:09 Speaker 1: I do 22:10 Speaker 1: not have any direct 22:12 Speaker 1: experience with them either of those. So, 22:15 Speaker 1: and don't have much anecdotal like experience than anybody else. So I don't want to give you any answers I don't know about. Okay. 22:23 Speaker 2: All right. Why is this so, this is a good 1. So why are there so 22:26 Speaker 2: much different information around Tesamorelin 22:29 Speaker 2: meaning why it gels up, 22:31 Speaker 2: has to be used in 3 days, in the fridge, don't put in the fridge, keep room temperature 22:37 Speaker 2: in the dark, 22:39 Speaker 2: mix it room temperature, mix it cold, 22:41 Speaker 2: etcetera, etcetera. Great question. You want to take that 1? Cause I know we've discussed it. It's very interesting. 22:46 Speaker 1: Yeah. 22:47 Speaker 1: Okay. So Tesamorelin 22:49 Speaker 1: is that, 22:52 Speaker 1: is 1 of these kind of like, 22:54 Speaker 1: well, all peptides are fragile, right? They're like living, 22:57 Speaker 1: living, but like amino acid chains that are really fragile. So all of them, this is why whenever you mix water in there, you don't want to blast the water in. You don't want to shake the thing. So Tesamorelin 23:06 Speaker 1: seems to be 23:08 Speaker 1: ultra sensitive. 23:09 Speaker 1: Okay. 23:10 Speaker 1: And it gels up. We knew a lot of people that were mixing like really cold water in and then getting it in and it was gelling up even, even putting as you're putting your water in just too fast. 23:21 Speaker 1: Right? So you really, 23:24 Speaker 1: it will make it gel up. It doesn't mean it's bad Tesamorelin. 23:27 Speaker 1: Just is it's because that is the compound. The higher the dose Tesamorelin, the easier it's going to do that usually because like a 20 mg is still coming in a 3 mil bottle. 23:36 Speaker 1: It's a max amount of water you can put in it. 23:39 Speaker 1: Therefore it'll jelly even easier. 23:41 Speaker 1: But so here's a suggestion. Now the 3 days, like mix it and use it all in 3 days. 23:47 Speaker 1: There's no evidence. 23:49 Speaker 1: There's no evidence I've come across that that's true. Even from the actual prescription manufacturer, 23:54 Speaker 1: it's like EGRIFTA or something like that, 23:57 Speaker 1: that makes it, 23:59 Speaker 1: they don't even say that. 24:01 Speaker 1: It, that may just be some, I don't know. Well, that's manufacturer Yeah. 24:07 Speaker 1: Or even right. 24:08 Speaker 1: Rumor from manufacturers. 24:10 Speaker 1: So people buy their stuff more often and use it faster than buy more. 24:14 Speaker 1: But here is the strategy. 24:16 Speaker 1: It will so 24:18 Speaker 1: really we'll also realize so 1st of all, mix room temp water. 24:22 Speaker 1: Okay. Then the Tesamorelin, if you want to store it in a cool, 24:27 Speaker 1: cool, 24:28 Speaker 1: not cold, 24:29 Speaker 1: not really cold and 24:31 Speaker 1: dark and dry place, 24:33 Speaker 1: that will be just fine. Okay. 24:35 Speaker 1: It'll it'll work and it will stay that way. The problem occurs when people put really cold water in. Right. Or they even put room temp water, put it back in their fridge and their fridge is like 1 of the people who keeps their fridge really, really cold. 24:48 Speaker 1: That's the, that is gonna be the problem. So if you can keep your fridge maybe a little bit normal, warmer than a normal recommended fridge, it'll be okay to put in there. Yeah. 24:58 Speaker 1: Likewise, 24:59 Speaker 1: or in a cool, 25:01 Speaker 1: mean, I probably not even up to 70 degrees, 65 degrees or so dark, 25:06 Speaker 1: dry cabinet. 25:08 Speaker 2: That's okay. That's also okay. But put room temp water in. That's new. I mean, that's, we've come a long way from that. I mean, we continue to grow and learn and we wouldn't have said that. I mean, we, in the beginning, I mean, if you looked at some of the stuff, like some of the podcasts a year ago, 25:21 Speaker 2: were injecting 25:22 Speaker 2: cold water because at the time that's what we thought we'd read that. 25:26 Speaker 2: Yeah, 25:27 Speaker 1: like anything cold water into the box. Yeah. Yeah. But now I keep my water out in room temperature. Yep. Kept in the freezer a little because there's lots of experience, but also it's because, you know, back way back when the new peptides are coming out all the time. When we started, 25:41 Speaker 1: there weren't that many peptides and the ones that were out 25:45 Speaker 1: were ones that weren't very fragile. Yeah, it's true. Right? And so then the new stuff comes out and they have other complications 25:52 Speaker 2: and they're delicate. Yeah, it's funny. I mean, Tesamorelin 25:55 Speaker 2: is definitely like an AOD. Those 2 gel up pretty commonly. I've just never had that problem with Tesamorelin. AOD I have, but not ever since we've been using acetate water in it. 26:06 Speaker 2: But yeah, don't know. A lot of people do. I've never had it. Yeah. 26:09 Speaker 2: And I guess just use it like everything else. 26:13 Speaker 1: If you're gonna do Tesamorelin, 26:14 Speaker 1: like don't also just don't let it be sitting mixed. Don't miss your doses. Leave it out a little bit. It'll Yeah, it might it might ungel. I often see people will send me like videos like, look, and it, you can tell that it's just halfway frozen. 26:28 Speaker 1: Warm it like you tell it's like about to turn into ice, which I think will basically ruin it also if it actually gets frozen. 26:36 Speaker 1: But use it. Okay. A 10 mg 26:40 Speaker 1: Tesamorelin 26:41 Speaker 1: generally, I think people should start at maybe 500 micrograms, 26:44 Speaker 1: test their tolerance, and then be, then bump up to 1000 26:48 Speaker 1: micrograms 26:49 Speaker 1: daily. 26:50 Speaker 1: So that would mean that the 1000 micrograms, a 10 mg bottle will last you 10 days. 26:56 Speaker 1: It'll be just, it'll be good for those 10 days. I promise you as long as it doesn't 27:01 Speaker 1: gel up. The same thing for 20 mg, 20 days, 27:05 Speaker 1: it'll be good for those 20 days as 27:07 Speaker 2: long as you don't allow it to gel up. And again, do not squirt the water on there very hard like a lot of people do. Yep. None of the pepatides. Don't do that. If you're gonna coach it, 27:19 Speaker 1: coach it to the side of the thing and just be like Yeah. Yeah. Let's put the needle in and then bend it, do this, and shoot it on the sidewall. Yeah. Let it go in. And if it's and it's really vacuumed, right, just kind of impede the plunger from just blasting the water in. You know? Depends on how big if you happen to use in, a 3 mil 27:37 Speaker 2: syringe, that water will go in fast if you let it. So don't let it. Okay, next. Cool. Alright. So, hey guys, huge fan and all in the peptide game with you both. I'm 38 year old man 27:49 Speaker 2: aiming for a body recomb, lifting weights 27:52 Speaker 2: 4 days a week at least and eating a high protein, 27:55 Speaker 2: tight diet. 6 weeks in to CJC Ipamorelin, 28:02 Speaker 2: 2 Migs recently increased AOD, 28:04 Speaker 2: 500 micrograms, 28:06 Speaker 2: Retta, 8 Migs just increased with CLO NAD 28:10 Speaker 2: and MOTS-C. My question is, when I am done with my 12 to 28:16 Speaker 2: 16 week cycle of GHRP 28:18 Speaker 2: and GHK-six, 28:20 Speaker 2: I want to keep up with the momentum. What are your thoughts on cycling on HGH 28:26 Speaker 2: HGH 28:27 Speaker 2: 1 to 2 IU per day during my rest period of peptides? 28:31 Speaker 2: Easy math. Yes, do it. You should be doing that anyway. 28:35 Speaker 2: Yeah. 28:36 Speaker 2: 38, 28:37 Speaker 1: 38. 28:38 Speaker 2: I would say just, you're obviously somebody that's 28:43 Speaker 2: into peptides as we are. You're 38, 28:46 Speaker 2: know, TRT and HGH. We've said it numerous times. I mean, that's a staple for me. 28:51 Speaker 2: 1 to 2 IU, 28:53 Speaker 2: you can run that, not necessarily in perpetuity, but maybe 28:57 Speaker 2: I plan to run it in very long periods and that'll just help you to 29:02 Speaker 2: lay your base and then you can add in secretagogues. 29:05 Speaker 2: Think, did you say CJC and Tesa? I wouldn't run those 2 together. I would run either or. 29:11 Speaker 2: And then the HGH in the morning, but the answer, my answer is very easy. Yes, do that. Dude, I don't know. I think that, 29:19 Speaker 1: you know, okay. 29:21 Speaker 1: Exogenous HGH like take there's like a ramp up period. Okay. It doesn't, 29:26 Speaker 1: we always say it's a, it's a long term play. Okay. 29:30 Speaker 1: I don't think frankly, it's a very good idea for you to do to like get on security dogs and pull out the HGH. 29:37 Speaker 1: So then now you're on security dogs 29:40 Speaker 1: for 12 weeks. And then as soon as you stop those at HGH in for, for 8 weeks and then pull that and then go back to security. That how you read that? I didn't read it like that. If 29:50 Speaker 2: he's just going do that for 8 weeks, if that's the case, then don't do that because it's not an 8 week play ms at The 29:56 Speaker 2: secretagogue sure. 29:58 Speaker 1: HGH is not an 8 week play. It's a lot longer. Yeah. It's a lot, it's a lot longer that that is pointless. And you're really just kind of, you're, you're not, 30:06 Speaker 1: I don't know. You're not me. You're really kind of throwing off your body's like pulsatile 30:10 Speaker 1: function, 30:11 Speaker 1: how it normally produces HGH. I would 30:14 Speaker 1: stick with either 1 or the other. Frankly, I would go either, Hey, just, 30:19 Speaker 1: can, you can keep running the security guards and maybe switch between like, Hey, go see if you're good with CJC, 1st of all, right? CJC Ipamorelin for 12 weeks and then go Tessa Ipamorelin for 12 weeks. 30:30 Speaker 1: That keeps your body's, you know, pulsing and that keeps a normal rhythm sustainable rhythm to it. 30:38 Speaker 1: Or 30:40 Speaker 1: just do the HGH that whole time. Okay? You could also add just Ipamorelin 30:45 Speaker 1: on top of just the HGH. 30:48 Speaker 1: Because again, 30:50 Speaker 1: the worry is that these secretagogues, 30:53 Speaker 1: if you run HGH, 30:54 Speaker 1: okay, 30:55 Speaker 1: and now a secretagogue on top, that secretagogue on top ain't gonna be doing much because the HGH is blunting 31:02 Speaker 1: that pituitary response. So it's just not gonna be really making more of its own growth. 31:07 Speaker 1: And I don't know anything just, just like, just like a bodybuilder bulks and 31:13 Speaker 1: cuts and bulks you like that, that is not good for a human body. 31:17 Speaker 1: With growth, we kind of wanna get it into a good rhythm and, and that's why HGH is a long play. Right? We want to get into a rhythm, doing the same thing and getting better and better ramping that up as opposed to just switching the way that the body makes it and receives it. It's confusing. 31:34 Speaker 1: So me, I don't know, despite how the question was asked, hopefully that gave an answer that you can apply. Yeah, that was good. Alright. 31:43 Speaker 1: 6. 31:44 Speaker 1: So my current stack is Reta 3 Migs 31:46 Speaker 1: once week 1, once weekly 31:49 Speaker 1: morning fasted 2 mg Tessa, once nightly 31:54 Speaker 1: fasted 2 50 micrograms of IpA once nightly fasted. 31:58 Speaker 1: I'm not sure there's no punctuation, so I don't know which goes with which, but fasted 1 mg Wolverine blend. 32:05 Speaker 1: 500 mgs BPC 32:07 Speaker 1: and TB-five hundred nightly, fasted 2 mg GHK 32:11 Speaker 1: CU nightly fasted. 32:13 Speaker 1: That's it, maybe. 100 micrograms 32:15 Speaker 1: B12 morning fasted started 32:19 Speaker 1: at 365, 32:20 Speaker 1: 12 16, 32:23 Speaker 1: started at 365. 32:25 Speaker 1: I think that's a weight pounds. Okay. On December 16, currently 3 38 32:31 Speaker 1: on February 14. Yeah. K. Good job. 32:36 Speaker 1: Resistance slash cardio 3 days a week. 32:39 Speaker 1: BBJ 32:40 Speaker 1: BBJ 32:41 Speaker 1: Muay Thai 3 days a week, 1,500 calorie 32:45 Speaker 1: intake daily, 32:47 Speaker 1: and typically around 125 32:49 Speaker 1: grams of protein and carbs, 50 grams of fat, feel amazing. Any suggestions and anything else to help with body recomp 32:55 Speaker 1: or cellular help? Any chances you guys would recommend? 32:58 Speaker 1: Any changes you guys would recommend? 33:01 Speaker 1: Why don't you start since I was 33:03 Speaker 2: studying through The 1st thing, and this 33:07 Speaker 2: is just, I don't know. I mean, 100 calories is pretty low. 33:11 Speaker 2: You're a big guy. Now you're trying to lose weight obviously, and that's great. I'm going to always tell you, I think you should do some 33:45 Speaker 2: And then on the weekends eat. I do that a lot and it's worked out great. I think that will help you. 33:50 Speaker 2: You're saying you're at your 33:54 Speaker 2: weight is 3 38 and you were eating 125 33:56 Speaker 2: grams. Would up the protein 33:59 Speaker 2: for sure. Eat more protein. I you're not eating enough, dude, to be honest with you. You're a big guy. 34:04 Speaker 2: And I know that's kind of a mind F to a lot of people. They think we're not supposed to eat, but you got to keep in mind that you got to keep your metabolism going. And if you're eating too much, it sometimes does the opposite of what you want it to do. So 34:18 Speaker 2: I would throw in some fasting and eat a little bit more when you eat. 34:22 Speaker 1: Okay, cool. I agree. 34:25 Speaker 2: Were you thinking that too? 34:27 Speaker 1: 1,500 is a little bit low, 34:29 Speaker 1: but here's the deal. Do not make a drastic increase on that immediately. 34:34 Speaker 1: If you are, if your body is used to eating 1,500 calories, if we say you should be eating more than you go up to 3,000, 34:41 Speaker 1: it's not going to be good. But like, so, but what I would do is start 34:45 Speaker 1: slowly increasing that number. And let's increase it by protein. You know what I'm saying? Like rats get more calories 34:53 Speaker 1: via protein, please. You're 34:56 Speaker 1: a big dude. So my general, I guess if you want if a person wanted to gain the most amount of muscle possible, okay, I think that 35:05 Speaker 1: 1.5 g of protein per pound of body weight 35:10 Speaker 1: is about what we can take in. Also, every time you eat, it takes about 2 hours for protein to 35:17 Speaker 1: and depending on your size, 40 to 50 grams of protein per serving, then it takes 2 hours for your body to actually digest and use that, shove it to your muscles. So like in a perfect world, 35:28 Speaker 1: taking and you're a big dude. So let's go with 50 grams per meal, 50 g of protein. I want an 35:34 Speaker 1: injection of 50 of protein every 2 hours, 35:37 Speaker 1: 20 fourseven. 35:38 Speaker 1: That way that's not real. We're not really actually injecting protein, but 35:44 Speaker 1: then you will gain the absolute most amount of muscle. Okay. And I know you're saying, Hey, I'm trying to lose weight, but like promise me, promise you like lifting weights and gaining muscle is, 35:55 Speaker 1: is going to make you burn fat and lose fat so much faster. Okay? Just the recovery time that your muscles are sore because you train them. That's the only way to build muscle is by working them out to soreness. Your body's burning a shit ton more calories. 36:09 Speaker 1: Just recovering plus every pound of muscle we had, metabolism 36:13 Speaker 1: speeds up by 50 calories a day. Okay? 36:17 Speaker 1: And that stuff adds up over time. So 36:20 Speaker 1: I would try to increase the caloric amount plus your your your your body burns 36:25 Speaker 1: pretty damn equal to the amount of calories you take in once it gets used to that. So 36:31 Speaker 1: you're just kind of killing your metabolism by eating a low amount of calories, 36:35 Speaker 1: whether you think so or not. It's about the macros of those calories. It's the most important. Always, I frankly just don't think calories should ever factor into anything. I don't care about calories. 36:46 Speaker 1: What we care about is macros. Right? I care about 36:49 Speaker 1: protein, fat, and carbs. Don't give a shit. Right? If you're eating 1,500, 36:54 Speaker 1: 1,500 calories and it comes from Twinkies, 36:56 Speaker 1: right? Or 1,500 calories and it comes from steak. There's a massive 37:00 Speaker 1: difference. I know there's some people's philosophies. Calories in Like that's been around for a long time. And I'll say calories in calories out makes you lose weight, but it's like, what kind of weight do you want to lose? 37:10 Speaker 2: Like if you're 1,500 37:12 Speaker 2: calories of donuts compared to 1,500 calories of like chicken and vegetables, very different. It's a night and day difference. So 1st of all, there's that 2nd. 37:21 Speaker 1: Let's 37:21 Speaker 1: that's great. It sounds like your exercise is really good. 37:25 Speaker 1: Is your sleep good? 37:27 Speaker 1: Sleep, sleep, sleep, sleep, sleep, deep sleep, right? DSIP for deep sleep will help. 37:32 Speaker 1: Dihexa even. 37:35 Speaker 1: Then you 37:37 Speaker 1: basically 37:38 Speaker 1: just know like you're going to be, this is a journey, right? You've kicked ass already from December to February. Okay. 37:45 Speaker 1: You've lost 20, 37:46 Speaker 1: 25, 27 pounds. That's really good. Okay. 37:50 Speaker 1: But this is going to be long term. Like it sure sounds like you are well on your way to making a good lasting life change, but 37:57 Speaker 1: results are going to be, mean, it's going to be kind of fun for you though, because you're going to see fast results, right? It starts to get really hard towards the end 38:05 Speaker 1: as you just need to lose a little bit more, right? So you're doing the right thing by not just 38:10 Speaker 1: losing 50 pounds in a month. Although you're on that, you're on that track since you lost 25 pounds and oh no, no, not in 2 weeks, 38:18 Speaker 1: in 2 months. So you're actually doing, you're doing this at a really healthy rate even 38:22 Speaker 1: based on that starting at $3.65. 38:24 Speaker 1: So like, yeah, you should be losing weight pretty fast at the beginning doing all these things right. 38:29 Speaker 1: So 38:30 Speaker 1: I just hate to, 38:33 Speaker 1: I just really want you to get into a rhythm of general health. Mitochondro, I'd still may MOTS-thirty 38:40 Speaker 1: 1. To get to 3 65 38:43 Speaker 1: pounds, you probably 38:44 Speaker 1: had to not be living the most healthy life. Okay? Therefore, 38:48 Speaker 1: my guess is your mitochondrial health, internal health, insulin sensitivity 38:53 Speaker 1: is not very good. 38:55 Speaker 1: So I think it would actually benefit you a lot. Maybe try to add in MOTS-three 39:00 Speaker 1: 1, 39:01 Speaker 1: which helps you give us more energy in your mitochondria. SS-thirty 1 basically makes that mitochondria a lot more efficient and healthy so it can use all of that energy. 39:09 Speaker 1: You might want to try that, see if you notice a difference, but you're feeling great, bro. Just 39:13 Speaker 1: stay the course, dude. Go with it. What is working and getting you results? Okay. Until you plateau, 39:19 Speaker 1: that is when it's time to switch everything up. Yep. Okay. So as long as you are losing weight at this rate, 39:27 Speaker 2: 1 thing that I don't think that we would 39:29 Speaker 2: probably won't when I say that you're going to catch it too. So why don't you try to do the microdose? You do it 3 mgs of Retta once a week. I know that's a lot of people think that that's the way to do it. We will say a little bit differently. Why don't you try? Why don't you try to do a MEG Monday, Wednesday, and Friday? You're a big dude too. You can go up on the Retta. I mean, that's a pretty low dose for a guy that you're is your side, so you could go up if you want. 39:53 Speaker 2: But 39:53 Speaker 2: either way, even if you stay at the 3 megs, 39:56 Speaker 2: do a make Monday, Wednesday, Friday, we have just found that it works better. 40:02 Speaker 2: Just try it. 40:03 Speaker 2: You can always go back. Absolutely. 40:06 Speaker 1: But dude, I don't know. Keep kicking ass. Like, let us know how it goes and ask us when you do plateau out. 40:12 Speaker 1: Cool. Write in, tell us, tell us what's up. Tell us what's next. All right. Go ahead. All right. Does Retatrutide 40:20 Speaker 2: have any effect on birth control as far as losing weight or effectiveness 40:26 Speaker 2: on the pill? And that was a good question. I've never heard that. Great question. Well, 1st of all, 40:32 Speaker 1: there's a lot of like secondary effects that potentially could have like, right going through big hormonal changes, like losing a whole bunch of weight while being pregnant 40:40 Speaker 1: is probably 40:41 Speaker 1: not a great idea. 40:44 Speaker 1: Plus, it's slowing the gastric emptying. It's basically just really, really slowing down 40:49 Speaker 1: food going through your intestines and your stomach. 40:53 Speaker 0: The perfect lunch combo. 40:55 Speaker 0: That 1st bite of your favorite sub followed by ice cold Pepsi. Add a couple of friends, and now that's next level. Suddenly, the laughs get louder, the stories keep flowing, and the food tastes better because Pepsi brings out more flavor, more fun, and more of the moment. 41:11 Speaker 0: Food deserves Pepsi. Grab a Pepsi 0 Sugar today. 41:16 Speaker 1: How do we how does a baby eat? 41:18 Speaker 1: It eats the food that you eat, right, and feeds the baby, 41:23 Speaker 1: so 41:24 Speaker 1: I would not pick that the time to starve myself. And when I just starve myself, I'm just talking about just general and GLP-1s. People just eat, start eating less food. Okay, even on Retta, because it makes you not eat as much during each sitting. So 41:38 Speaker 1: I wouldn't do, I wouldn't do Retta just because of the secondary effects. I don't think I actually write read up on this. I don't think there's any 41:45 Speaker 1: like direct effect, 41:47 Speaker 1: like something in Retta is really like gonna harm the baby, but 41:53 Speaker 1: those secondary effects, you know, keep your babies when we get fat while they're pregnant for a reason, dude, because you need to eat. You're eating for 2. Sorry. You just gotta I'd error on the more nutrients to give that baby. 42:05 Speaker 1: Also, we do know if we're talking like pre, 42:09 Speaker 1: if you're trying to get pregnant, 42:12 Speaker 1: you know, women who are doing bodybuilding shows, you get down, women get down to below like 17% 42:16 Speaker 1: and they stop having their period. Because 42:20 Speaker 1: God goes, yeah, you don't eat enough food for 2. So you don't have enough fat on you for 2 people, so you shouldn't be having a baby. 42:29 Speaker 1: So I wouldn't you're not gonna wanna do that and put yourself in that 42:33 Speaker 1: Yeah. 42:35 Speaker 1: She's pregnant 42:37 Speaker 2: though. That's what she's trying to do because birth control, is it affecting like, I think what she's trying to get out is if she's on the pill 42:44 Speaker 2: is taking Retrutide 42:46 Speaker 2: going to basically dilute it and my understanding is it can, I don't think it will? 42:52 Speaker 2: It can 42:53 Speaker 2: just by like slowing down the absorption of 42:56 Speaker 2: the pill. 42:59 Speaker 2: My 43:01 Speaker 2: somewhat guesstimation for just logic is I don't think I think you'd be fine. Yeah. I think you'd be good. 43:08 Speaker 1: Fertility will increase as you get as you get more estrogen, more fat, more estrogen, more estrogen, 43:13 Speaker 2: more fertility also. All right. Am I up? Yeah. Am I up? Yeah. Okay. 43:19 Speaker 2: Hi guys, as always, thank you for bringing such great information and insight to the world of peptides and wellness. 56 year old woman here, fit, active, and closing in on those last 5 pounds after the significant weight loss journey. 43:32 Speaker 2: Hoping to lose another 2 to 3% body fat, which is going to take some time. Question about using Ipamorelin without Tesamorelin 43:40 Speaker 2: or other GH secretagogues. 43:43 Speaker 2: I'm finishing up a 12 course of Tessa, 43:47 Speaker 2: AOD, 43:47 Speaker 2: GLOW, and ongoing RETA. 43:49 Speaker 2: I hadn't tried Ipamorelin before because I was concerned about 43:54 Speaker 2: grilling ghrelin interfering with my recomp and weight loss goals, but your recent podcast made me think that the hunger pulls might be completely manageable and 44:04 Speaker 2: not contradict 44:05 Speaker 2: what the Red Eye is doing. So I'm interested, would it be worth trying Ipamorelin 44:09 Speaker 2: on its own alongside Retta with some sloop? 44:13 Speaker 2: Or 44:14 Speaker 2: should I wait 6 or 8 weeks until I start another round of Tesa? Thanks so much for your feedback. That was a great question. Yeah. 44:21 Speaker 2: I don't think that's in, I don't personally think that the hunger of Ipamorelin, 44:27 Speaker 2: I don't even notice it. I mean, I know that's some of the job of it, but 44:32 Speaker 2: you know, we've talked about comparing it to like a MK-six 77 and that will make you hungry. It will make you hungry. 44:40 Speaker 2: Ipamorelin, 44:41 Speaker 2: I've done countless times, I've never even noticed a difference in hunger at all. So, 44:47 Speaker 2: my answer to that is I think you're fine. I think you're good. I wouldn't even worry about that. You seem to be a pretty conscience gal anyway. 44:54 Speaker 2: So I would do that. And then 44:57 Speaker 2: it's a matter of an opinion. 44:59 Speaker 2: I think Tessa Ipamorelin together are great. Can you do Ipamorelin? Sure. I mean, I think Ipamorelin for a woman would go a really long way. I think you'll get a little bit of a tone, 45:08 Speaker 2: toneness, but why not do the Tesamorelin because it's going to burn that belly fat too. 45:12 Speaker 2: So I'm going to on the side of do the test of Ipamorelin. Why not? 45:17 Speaker 2: And don't worry about the hunger. You're going to be good. Yeah, I would agree. I don't think that the 45:23 Speaker 1: hunger caused by Ipamorelin is all that much And you're right because 45:27 Speaker 1: of the ghrelin receptor. 45:28 Speaker 1: I 45:29 Speaker 1: think it'll do more plus you're taking Retta. I would. So yes, I would say to answer the question directly, 45:35 Speaker 1: hell yeah, I would take Ipamorelin all by itself and SLU-3s. Okay. 45:39 Speaker 1: On top of those. And then if you want to wait for your another round of Tesa, then just add that Tesa back in. So you're doing Tessa and Ipam then at that point, 45:47 Speaker 1: you'll 45:48 Speaker 1: love it. On. And you know, you're 56 and you gotta lose that last pound of 5, 5 pounds, right? Like that takes discipline and good for you to get after it. But like, that's going to be hard. It is hard and it's going to take some discipline, right? Abs, abs and all this stuff made in the kitchen. So 46:06 Speaker 1: watch, you know, eat and be disciplined. 46:09 Speaker 1: Yeah. She's there. Can tell. Yep. Sleep. You're up. Sleep. All right. Hi, I'm 48 years old 46:16 Speaker 1: type 1 diabetic female and would love your thoughts on peptide use specifically for T1D individuals. 46:23 Speaker 1: Context, I'm five'seven, 126 46:25 Speaker 1: pounds and have lost 48 pounds 40 pounds 46:28 Speaker 1: using tirzepatide and ritatriptide. 46:31 Speaker 1: Currently running Reta 1 mg every 4 days, 46:35 Speaker 1: glow 5 days per week, AOD 46:38 Speaker 1: 9504, 46:40 Speaker 1: 5 46:42 Speaker 1: days per week. I recently finished the cycle with Tesla Ipi, and I absolutely loved how I felt on it. I'm feeling really good. Now focusing on building more lean muscle. I did deal with a bit of skinny fat early on after the weight loss. My question is, are there any peptides, stacks, or cycling considerations you found particularly helpful 47:00 Speaker 1: or things to be cautious with for people with type 1 diabetes? 47:04 Speaker 1: I'm currently working on 47:06 Speaker 1: calendaring it, calendaring a year long peptide cycling plan. Would love any high level guidance or principles to keep in mind for T1D specifically. 47:15 Speaker 1: You all for your education 47:17 Speaker 1: you put out. So 47:22 Speaker 1: I would 47:23 Speaker 1: not take regular 47:25 Speaker 1: HGH. 47:27 Speaker 1: Okay. 47:28 Speaker 1: That doesn't sound like you wanted to, but while you're taking any of these secreted gugs, 47:34 Speaker 1: I would keep getting your blood I mean, it's you're you're measuring your own blood, my guess is. 47:40 Speaker 1: So if you did great and you felt great with that, 47:45 Speaker 1: do on those that's kind of, I would say that that's 47:48 Speaker 1: the secretagogues 47:49 Speaker 1: are the biggest worry on 47:52 Speaker 1: anybody who 47:54 Speaker 1: has insulin issues or diabetes. 47:58 Speaker 1: Gosh, I don't know. I don't really have much more like you're doing. 48:02 Speaker 2: I mean, you could take out the secretagogues 48:04 Speaker 2: and just go with AOD, 48:06 Speaker 2: you know? Yeah. Absolutely. 48:08 Speaker 2: Just take it to see your drugs and not even mess with it. We're going to, Will and I just known a long time, so I know I can speak here when I say that we're always going to air on the side of caution. Like, why not? You have so many dang 48:19 Speaker 2: peptides 48:20 Speaker 2: out there that are rad. So like throwing SLU-0.0, throw an AOD, take out the secretagogue and just be safe. I think you're going to get equally as much out of it. 48:28 Speaker 2: What do you think? Yeah, I think so. I mean, just kick the kick the secretive 48:32 Speaker 2: goggles through the curve, man. AOD is amazing. 5 amino-1MQ 48:36 Speaker 2: is amazing. SLU-3P-thirty 48:38 Speaker 2: 2, amazing. Those are 3 compounds that are not secretive goggles and they are awesome. 48:43 Speaker 2: So I would do that. 48:44 Speaker 1: Yeah. I think that everything else, all of the, if you want to do 48:48 Speaker 1: the fat burner, AOD is great. 48:51 Speaker 1: 5 m 1 MQ is just fine with type 1 diabetes. 48:55 Speaker 1: Sloop is just fine. 48:57 Speaker 2: Stack them too. I mean, if you're trying to like lose weight and, you know, burn fat, I mean, you can stack those. They go really well together. 49:06 Speaker 2: And again, just be safe. Worried about that. Just, you know, it is a great worry. 49:11 Speaker 1: Why mess with it? Growth hormone, the growth hormone 49:15 Speaker 1: products 49:16 Speaker 1: are the worst 1, are the ones that you need to worry about. Frankly, everything else is either 49:21 Speaker 1: a non factor or is helpful. 49:24 Speaker 2: Okay. So 49:26 Speaker 1: that's, that's all I got, but I don't mean to, yeah, just keep doing what is it? Being consistent. 49:34 Speaker 1: Right. You're up reading. Am I taking this home? Yes. All right. 49:39 Speaker 2: Hey guys, I love the podcast. Thanks for putting so much knowledge out there. I have a few questions and 49:44 Speaker 2: would appreciate any guidance when you get a chance. 49:47 Speaker 2: I'm 35 year old female who strength trains regularly, 49:51 Speaker 2: tracks my diet closely. 49:53 Speaker 2: Like many of us, I am chasing the dream of getting lean while maintaining muscle. 49:58 Speaker 2: Don't worry, I have my Retta already 50:01 Speaker 2: in order after all you guys have to say about it. I previously ran IpocJC, 50:06 Speaker 2: very popular compound, right? 50:09 Speaker 2: And love the results, especially this sleep. During my 1st cycle, I developed a well, red welts. Here we go again at 50:16 Speaker 2: the injection site that 50:18 Speaker 2: lasted a few days, but I pushed through it On my 2nd cycle, 50:22 Speaker 2: about 2 weeks, I started getting full body hives. 50:26 Speaker 2: The hives resolved 50:28 Speaker 2: within 2 to 3 days of stopping Ipamorelin. I've 50:31 Speaker 2: since switched to Tesamorelin, 50:33 Speaker 2: but I'm not seeing the results as impressive as I did of the Ipamorelin. 50:38 Speaker 2: It's because CJC is just more stronger. 50:40 Speaker 2: I remember it being a mentioned that KPV may help reduce allergic reactions. It will though at the time I broke into hives, 50:50 Speaker 2: I was also taking Clo. 50:52 Speaker 2: I'm not sure if the reaction was from Ipah, CJC or combination, 50:57 Speaker 2: so I'm hesitant to retry without guidance. 51:00 Speaker 2: Is there any alternative you'd recommend stacking with Tesamorelin instead? 51:05 Speaker 2: After listening to the podcast, 51:07 Speaker 2: I started MOTS- C huge game changer for energy and focus. I run it with NAD plus which I like, but MOTS-1C really stands out for me. I'm considering adding SS-thirty 1 as well. What protocol would you recommend with running NAD MOTS-1C 51:24 Speaker 2: and SS-thirty 1 together? Question mark, 51:27 Speaker 2: should they be stacked on the same days or staggered? 51:30 Speaker 2: Great question, All 51:32 Speaker 2: right. I can give you some answers on this 1. So, A, so you got a reaction twice to C2, CJC and Ipamorelin. All right. Well, that was the CJC Ipamorelin. My guess is the reaction was to the CJC, 51:46 Speaker 2: by the way, 51:48 Speaker 1: twice. So don't do that 0.333 time. Right? But you also got a reaction to Clo. 51:54 Speaker 1: Or was it Glow? I think that she was saying that the Clo- 51:59 Speaker 2: Because she was saying it had KPV, so maybe she was saying that that helped. Well, 52:03 Speaker 1: it may help reduce allergic reactions, 52:05 Speaker 1: though at the time I broke into hives and I was also taking Clo. Well, okay. So KPV, 52:10 Speaker 1: so 1st of all, KPV 52:12 Speaker 1: is helpful for your gut and helps with your immune 52:16 Speaker 1: system. It is not 52:20 Speaker 1: a straight up antihistamine. 52:24 Speaker 1: Like a So Benadryl 52:25 Speaker 1: is the thing that is going to help the, the, the reactions. 52:29 Speaker 1: Okay. Clo. 52:31 Speaker 1: It might help. It's worth a try. And 52:34 Speaker 1: it could help, but 52:36 Speaker 1: it's all you got. 52:38 Speaker 1: But Benadryl is like the guarantee we will fix it. Now. I still think that the reaction is probably not safe for you to go, well, screw it. I'll just take CJC, Ipam and a Benadryl every time. Not a good idea. 52:49 Speaker 1: Now if you did happen to react, so therefore the KPV and CLO may just not, you still had a reaction. The KPV wasn't strong enough in there. Or, 52:58 Speaker 1: Hey, sometimes people are, 53:01 Speaker 1: can be allergic to the binder fillers that are put in these peptides when you do make a blend. Okay. So they have to put something different, 53:10 Speaker 1: in there when they actually blend a couple peptides together. 53:13 Speaker 1: And I know some of those, I read a big long article about an employee for a lab, like literally couldn't, she couldn't hang out with her friends 53:21 Speaker 1: if they wore the lab coat, which touched their regular clothes, 53:25 Speaker 1: like 16 hours later, if they were making any blended pipettes. So she was that allergic to that binding that binding chemical. That's crazy. Yeah. Like it was like bad. Like she almost died the 1st time that she was in there when they started doing it. 53:38 Speaker 1: So some people can be allergic to the 53:41 Speaker 1: actual blends. 53:44 Speaker 1: You taking Tesas, you said, Hey, I didn't have a great, didn't really notice much. Well, it could be, I don't know what you were taking for dose timing, 53:53 Speaker 1: you know, 53:54 Speaker 1: fasted or not fasted. 53:56 Speaker 1: Also you weren't taking Ipamorelin. 53:58 Speaker 1: I don't think CJC is the culprit usually. Okay. Not Ipamorelin. 54:01 Speaker 1: Just happen to have always have CJC blended with Ipamorelin. 54:05 Speaker 1: I would still give Tessa Ipamorelin a fighting shot. Yeah. Now I might also have a bottle of Benadryl next to you. 54:13 Speaker 1: In case you were allergic to that too, 54:16 Speaker 1: that blend. But 54:18 Speaker 1: kick ass, go with I mean, I'm glad to hear that the MOTS-3C and NAD is really a game changer. So you asked here, I can't answer this direct question. Here's what I would do on the protocol 54:28 Speaker 1: with the MOTS C SS-thirty 1. I like doing 1 mg of MOTS C daily 54:36 Speaker 1: and then between 5 54:38 Speaker 1: to 10 or maybe even a 15 Migs 54:41 Speaker 1: daily 54:42 Speaker 1: of the SS-thirty 1. That's 54:45 Speaker 1: too high. But like I wouldn't do any less than 5 mg of SS-thirty 1. Sorry. I just wouldn't. 54:50 Speaker 1: But so I do MOTS-1MIG 54:52 Speaker 1: and SS-thirty 1 at least 5 mgs daily. 54:55 Speaker 1: It doesn't matter. Daily timing of those 2 54:58 Speaker 1: doesn't really matter. Right? That's not really going to make a difference. 55:02 Speaker 1: Since you're already taking SS-thirty 1, I mean, you're already taking MOTS-thirty you might just add the SS-thirty 1 in. Yeah. Hell yeah. If you asked us, we've had this question before and we answered it in the, in discussed it. If you asked us, which should I, if I want to take SS-thirty 1 and MOTS-three, 55:17 Speaker 1: okay, I want to take them, but if there were 1 that I wanted to start 1st, like a month before I introduced the next, which would it be? And the answer, 55:26 Speaker 1: well, my answer is now that thinking about it is the SS-thirty 1 1st, because that is what is strengthening the integrity of the mitochondrial wall, right? So I don't care, you add MOTS-1MQ 55:38 Speaker 1: in and you don't have any good integrity of the mitochondrial wall. Great, it's pushing energy and that energy is just floating out in the universe and not doing anything. That's not helpful. So let's make the, the, the, like the housing unit very strong, 55:51 Speaker 1: then add the energy in and now it will really work and harness that energy correctly. 55:56 Speaker 1: So that was my answer. The NAD, 55:59 Speaker 1: frankly, I think 15 mgs a day. Yeah, daily. 56:03 Speaker 2: Daily. A lot of people do it like 3 times a week. Don't know. I do daily. Think so. So 56:08 Speaker 2: you can get away with 3 times a week. Depends on your objectives. I use it as a coffee type deal. So those 56:14 Speaker 2: 3 together though, you just nailed it are amazing. 56:17 Speaker 1: Are so light your mitochondria up baby. So you're rocking and rolling. Good job. Thank you guys, JD. Thank you for getting through this. It was a rough weekend at the Denham household 56:27 Speaker 1: with his wife and- A 56:29 Speaker 2: lot of stuff going on. So we got through. Having issues and yeah, so 56:34 Speaker 1: we are good to And 56:37 Speaker 2: then I called Will this morning. I'm like, coming in a little late today. I'm sleeping like shit, but we got through it. Always enjoy this either way. We love the Q and A and the next 1 we will be doing, 56:48 Speaker 2: pep out of the week. So that'll be next. Anything else? Yeah, I get to use my, I get to give you all some visual learnings. I'm excited. He sure does, man. But, we will catch you guys next round. Yep. Later.