Peptide of the Week: KPV & PT-141 – Gut Health, Inflammation & Libido Peptide of the Week https://peptideoftheweekpod.com/episodes/peptide-of-the-week-kpv-pt-141-gut-health-inflammation-libido/transcript We are not doctors. The content on this site is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Amounts, timing and cycle lengths below are reported as the named speaker described them. Nothing here is a protocol to follow. --- 0:08 Speaker 0: Welcome back to the 5th time of the week podcast. 0:11 Speaker 0: I'm your host JD Denham, sitting in the podcast room, nice and cozy and in 0:17 Speaker 0: rainy, 0:18 Speaker 0: but beautiful 0:19 Speaker 0: South Carolina, 0:21 Speaker 0: Will is 0:22 Speaker 0: getting ready to go to a wedding. He's supposed to be laying by a pool, but weather did not allow that. Yes. Weather's not permitting. So we're in basically we're in Myrtle Beach, South Carolina. 0:36 Speaker 1: Which is gorgeous. I heard it's gorgeous there. Yeah. Apparently also this is like the site of the, like most shark attacks in The United States. And 0:45 Speaker 1: they're all bull sharks too. Oh, wow. You know, those guys are mean aggressive and they can go swim up into fresh brackish water, they say. Yeah. 0:56 Speaker 1: And looking outside in the waves like this, the water looks very sharky. It is not clear. Like you cannot you can't see an inch away from 1:06 Speaker 1: anywhere in that water. 1:08 Speaker 0: 0 chance in hell that I would go in that water. 1:12 Speaker 0: 0. I don't know if I ever told you the story. So like, if anybody ever asks, I don't, you know, it's funny that everybody thinks I surf because we live in Huntington Beach, but I don't. And I blame my parents. 1:23 Speaker 0: So when I was too young, I don't know the age exactly, but you know, if you're listening to this, dad, I blame you. They 1:30 Speaker 0: let me watch Jaws when I was a kid. I've never been the same. 1:34 Speaker 0: Never been the same. I never wanted to go in the damn ocean after that movie. I never recovered, dude. So, you know, obviously when you're scared of something or I don't know if everybody's like this, I'm intrigued by it. You want to learn about it? So obviously shark week and all that stuff. As you said, bull sharks, those are the worst sharks, dude. Those things have no mercy. 1:54 Speaker 1: Will get your face off. Yeah. Just for the fun of it. 1:58 Speaker 1: Absolutely. And no doubt. I don't blame you on this. I mean, and sharks are impressive animals. It's kind of fun to watch them from a TV screen. 2:07 Speaker 1: Not in the actual 2:09 Speaker 0: wild next to you. Do you see when I got 2:12 Speaker 0: married, 2:13 Speaker 0: go out, we, we, our, 2:15 Speaker 0: we went to Maui is where we stayed for 2:19 Speaker 0: the next week or so, you know, after. And 2:22 Speaker 0: we were going to go on like a shark expedition, but she 2:26 Speaker 0: wanted to go in the damn shark cage. And I'm like, that's a freaking lutely not dude. Like you ever seen those like videos where the shark gets in the damn hole? Like my new bride, like honey, you ain't going in the damn shark cage now. Lucky I lucked out because they didn't have that on Maui. They'd have another only cage that's not Maui. So I'm like, Dude, my wife's so funny. Dude, then in Florida, we took a vacation to Florida. We went on this, 2:48 Speaker 0: alligator, 2:49 Speaker 0: like in the dunes or wherever, 2:52 Speaker 0: and like boats. My wife is sitting on the edge, 2:55 Speaker 0: Alligators like swimming all around, like she's like, put I'm like, what the 2:58 Speaker 0: her on the other side What are you doing? Like, what? 3:01 Speaker 0: My wife did. 3:03 Speaker 1: God love her. You know, I wouldn't do the shark cage in Maui either because, I mean, there's no great whites. There's sharks that they're gonna see there, tiger sharks, they're pretty big, 3:12 Speaker 1: but still I would, I would rather do what I'm saying. I'd rather go in the shark cage with great whites because then they can't get in. It's the little sharks that can get in there and Alyssa could get yanked right through those, 3:24 Speaker 0: Put her hand out, My wife is just, she's smart, but does dumb stuff. 3:29 Speaker 0: Honey, I know you're listening. Yeah. Well, 3:32 Speaker 0: we're getting back to kind of the roots of where this all began, man. And we haven't had, we haven't been separated by a screen in quite some time. I'll have to be honest with you. I like sitting across from you, dude. A little more organic. 3:47 Speaker 1: It's a lot better in person. It's a lot better in person, but, 3:50 Speaker 0: at least we're used to this. This isn't like completely foreign. We did this for a while. And it's cool because like technology is pretty dope, dude. You're in, you're in South Carolina. I'm here in California and look what we're doing, man. So let's get you rolling because you need to get back to your trip. You need to like get with your girl 4:07 Speaker 0: and do all that, that fun stuff in the rain. 4:11 Speaker 1: So today, at least it's a little sunny today. So like we might as well 4:15 Speaker 1: walk out, walk out into the beach and not go swimming, but yeah, gloomy here too. 4:19 Speaker 1: So May, 4:21 Speaker 1: gray, June gloom. It's crazy in Southern California. It's like gorgeous all summer. Summer is like 9 months long, but May and June 4:28 Speaker 1: are terrible. Like always, 4:30 Speaker 1: well, especially June. It's just gloomy the entire time when you thought summer was so bad right now. Looks like it's gonna rain. Yeah. 4:38 Speaker 1: Crazy. But it's all good. It's still humid here. It's still warm. It looks like it's, you know, 50 degrees outside and you walk outside and it's probably still 75 4:45 Speaker 1: and humid, 4:47 Speaker 1: but raining. 4:48 Speaker 0: Crazy, 4:49 Speaker 0: I did a lot of mortgages in South Carolina and North Carolina, and man, they have gorgeous, 4:54 Speaker 0: gorgeous homes. 4:55 Speaker 0: Never been there, but I've just seen the homes and they're gorgeous, man. A lot of most people have lake acres and stuff like that. So cool. Cool. Everything, every house around here, every house around here is on stilts. Yeah. 5:08 Speaker 0: By the beach. 5:11 Speaker 1: Everything is on stilts for 5:13 Speaker 1: hurricanes and flooding. It's a real, it's a potential thing. 5:18 Speaker 0: Which they deal with a lot, man. Everybody's worried about California and earthquakes, man. When's the last time we had an earthquake that we even like really did anything. Even shook us to the degree where you're worried. It's been a long time. Yeah. It's been a long, long time. 5:30 Speaker 1: Don't even do All that, 5:31 Speaker 1: right. 5:32 Speaker 0: Well, here today, we're going to bust out too quickly. These will be easy ones. These are great, 5:37 Speaker 0: great peptides. 5:39 Speaker 0: Now, a lot of times I think people wouldn't think that 5:43 Speaker 0: inflammation 5:44 Speaker 0: and gut health and 5:46 Speaker 0: sex would all kind of go together, but they kind of do because when you're stressed, 5:51 Speaker 0: you get inflamed and that affects your hormones, which affects your sex 5:56 Speaker 0: and all these things. These 2 actually, believe it or not, people wouldn't think they go together, but I think they do. So we're gonna talk about KPV, 6:04 Speaker 0: which is a great 1. We have done this a long time ago. I think this has been almost a year. And then the 2nd 1 is 6:10 Speaker 0: everybody's 6:11 Speaker 0: favorite, PT-one hundred 41, which will be very easy. And if you haven't heard of it, you must be living under a rock. So let's jump right in, man. Let's start with KPV. 6:20 Speaker 0: PT-one hundred 41 is pretty easy. Let's start with KPV, man. Tell us a little bit about it. Okay. So I guess your 1st statement saying, you know, you don't think that 6:43 Speaker 1: like hormone. And both of these are derived from that. So it's interesting. They are basically from some of the same, same piece. But 6:51 Speaker 1: that and that that hormone stimulates, you know, well, controls 6:55 Speaker 1: inflammation, skin pigmentation, 6:57 Speaker 1: appetite, immune response now, but KPV 7:00 Speaker 1: is 7:02 Speaker 1: basically its main thing is anti inflammation. 7:04 Speaker 1: Okay. So that is it's that's the general underlying 7:09 Speaker 1: current of KPV is anti inflammation. 7:12 Speaker 1: Now it's actually, it's it's light, it's made up of 3 amino acids. So it's a very short chain and a very simple thing. Body makes it naturally. 7:22 Speaker 1: So there people aren't going to see any like histamine reactions because our body recognizes it as ourselves. 7:29 Speaker 1: And therefore the side effect profile is like nonexistent. 7:33 Speaker 1: So there's no such thing really as too much. I don't think, but, but then again, more isn't necessary. There comes a, there comes a point where there's diminishing returns once you get to a certain dose. Absolutely. Kind of unlike BPC where it's like, you do 10 mg of BPC in an injection, 7:50 Speaker 1: it will work a lot better than 1 mg and you know, it'll work 7:55 Speaker 1: even better. You know, 9, 10 is better than 9 and actually, you know, equally as we go KPV, 8:02 Speaker 1: we're looking at, you know, 0.5 mg, maybe 1 mg 8:05 Speaker 1: maximum, anything more than that. It's just kind of a waste of money. But 8:09 Speaker 1: so the cool thing is so anti inflammation, it is unlike ibuprofen or an NSAID 8:14 Speaker 1: non steroidal anti inflammatory. 8:16 Speaker 1: Those just tell they say, Hey, master switch inflammation in your whole body, shut it off. No inflammation anywhere. Even the good inflammation. 8:24 Speaker 1: KPV 8:25 Speaker 1: will actually go find things that are 8:28 Speaker 1: ultra inflamed and will just target them. It will really selectively choose 8:35 Speaker 1: to lower inflammation, anything that is too inflamed 8:38 Speaker 1: as opposed to just shutting off all inflammation 8:41 Speaker 1: whatsoever, 8:43 Speaker 1: which 8:44 Speaker 1: is actually kind of elegant and nicely designed, but it's a small amino acid. So it's very small, small peptide, very small, and we'll get in and do its specific signaling job. 8:56 Speaker 1: Gut. So I guess where, I mean, 8:59 Speaker 1: gut health, is definitely, it's gonna, it's going to, so this and BPC taken together is the best way to kind of heal, heal a person's gut. And KPV 9:09 Speaker 1: is there to calm down cytokines when we basically have some inflammation going on or an autoimmune reaction, our body produces all these cytokines and they go crazy and they cause more inflammation everywhere. 9:22 Speaker 1: This calms them down, gets rid of them, creates an environment 9:26 Speaker 1: so that it can be healed. The BPC comes in and does the actual 9:31 Speaker 1: repairing of tissue 9:33 Speaker 1: work. 9:35 Speaker 1: I know that you are, 9:37 Speaker 1: you know, you're dealing with a lot of gut issues, but it is definitely going to help with the gut. 9:44 Speaker 1: I don't know. What else do you got to add on that? Think, I I think, 9:48 Speaker 0: well, you know, I think a lot of people aren't going realize like that 1 of the main qualities of it is inflammation because it's known for gut. I think that's if people that know about it, they're going to think about gut 1st, but it's going to bring down inflammation. So I think it would be good to be ran with 10:02 Speaker 0: ding ding ding TA-one. 10:04 Speaker 0: I think those 2 would be good for 10:06 Speaker 0: inflammation, 10:08 Speaker 0: depending on what your objectives are. If it's gut health, then you wanna kind of take a left turn and you wanna add in the BPC-157, 10:15 Speaker 0: because they'll work really good in tandem. I mean, what are some of the problems that are plaguing 10:20 Speaker 0: everybody basically 10:21 Speaker 0: with gut issues? You got leaky gut that, you know, even doctors are finally coming around and admitting that leaky gut is there, 10:29 Speaker 0: which, 10:30 Speaker 0: you know, so many things, you know, they say this, the gut's 2nd brain. I mean, that's been out there for a long time. I think that we all agree that that's the case. 10:39 Speaker 0: So many people, of the air, 10:42 Speaker 0: the food, 10:43 Speaker 0: sugar, 10:44 Speaker 0: seed oils, 10:46 Speaker 0: you know, just the food is fake. It is absolutely 10:49 Speaker 0: destroying 10:50 Speaker 0: our gut biomes and causing 10:53 Speaker 0: just countless autoimmunions. 10:55 Speaker 0: I mean, how many people do you know that has an autoimmune? You could probably talk with most. 11:00 Speaker 0: Yeah, probably. Yes. Yeah. So taking it and, 11:05 Speaker 0: and, you know, trying to work on some of that stuff where if you have some, you know, eczema or psoriasis 11:13 Speaker 0: or I mean, pretty much any type of autoimmune, 11:17 Speaker 0: it's going to help with that type of stuff. 11:20 Speaker 0: And that's just where a lot of people are sick. You know, I mean, what are some of the, again, processed foods, 11:26 Speaker 0: Stress, 11:27 Speaker 0: as we've talked about lately, 11:29 Speaker 0: Will, is just 11:31 Speaker 0: lack of sleep, 11:34 Speaker 0: high stress. 11:37 Speaker 0: Those 11:37 Speaker 0: 2 things in particular 11:40 Speaker 0: are so huge in affecting our lives in so many different ways where 11:46 Speaker 0: I've tasted it recently 11:48 Speaker 0: and never have really experienced just the power of cortisol. 11:53 Speaker 0: Cortisol is a deadly beast, man. That stuff, if you spike your cortisol, dude, it's going to mess you up in so many ways, you know, and you've heard my story recently. I've dealt with some of that stuff because I was going so long with lack of sleep. Finally it just said, boom. 12:08 Speaker 0: And man, I had this little pocket of fat that was chilling in my stomach and, you know, I'm on pretty, pretty easily fairly ripped. And dude, I could not get rid of it. And you know me, I researched the hell out of it. I'm like, what the hell is happening right now? Cortisol, dude, sleeping, 12:24 Speaker 0: So we live in a world where people drive an hour and 0.5 to work and an hour and 0.5 home. If that's you, I feel horrible for you. I don't think I ever could do that. But people do that spiking. You know, you're just, that stuff is just not just the food we eat, the air we drink, just the stress, man. 12:42 Speaker 0: Is brutal on our guts. Let's talk about the obvious also. 12:47 Speaker 0: Antibiotics, 12:49 Speaker 0: Antibiotics, 12:50 Speaker 0: you know, and it's gonna be a matter of opinion on that. You know, I don't know if anybody saw, you know, Scott come on the show, but he's 12:57 Speaker 0: highly, 12:58 Speaker 0: highly, highly against antibiotics. Now they have their 13:01 Speaker 0: purpose to where it's like a detrimental, 13:04 Speaker 0: like you need this to stay alive. But other than that, just destroy these things, just destroy our gut 13:12 Speaker 0: biome. And these are things that are like cascading events that follow. 13:17 Speaker 0: And that's why I think so many people have these damn autoimmune issues. 13:20 Speaker 0: So if you're listening to this and you have an autoimmune, 13:25 Speaker 0: I do too. I talk about it all the time. I got this damn head thing that I've been dealing with for years. 13:30 Speaker 0: I took a break from peptides and finally taking it this month and back on them. Was telling Will before we started recording, Damn, I'm gonna start taking KPV today, baby. It's been a while. So, you know, I hadn't taken it in a while, but, 13:42 Speaker 0: just doing a little studying before the show. It's, it's great, man. It's like, as you said, 3, 3, it's 3 amino acids and it carries a big punch for what it does, dude. So 13:53 Speaker 1: yeah, let's like outline the, so here's 13:56 Speaker 1: the kind of classifications. If you have 1 of these, this is, I would absolutely suggest KPV, 14:01 Speaker 1: right? So anybody with like diagnosed 14:04 Speaker 1: Crohn's, ulcerative colitis, 14:06 Speaker 1: microscopic colitis, 14:09 Speaker 1: anybody with IBS, leaky gut. Okay. So 14:14 Speaker 1: any in any inflammatory skin condition. When I started this, I said it was from the, this originates from that, 14:22 Speaker 0: Melanocyte, 14:23 Speaker 1: which which that controls 14:26 Speaker 1: our skin pigmentation. 14:27 Speaker 1: Therefore, 14:28 Speaker 1: this is absolutely going to help and heal and reduce inflammation of any skin disorders, including eczema, psoriasis, 14:35 Speaker 1: chronic acne. 14:38 Speaker 1: You know, it will help reduce inflammation from that. Rosacea, 14:42 Speaker 1: anybody who is a hard, if you're working out constantly, right? And therefore you have inflammation everywhere. And some that's good. That's how we build muscle. You know, we want to, a bodybuilder wants to cause inflammation. They want to tear the hell out of your muscles while you're in the gym, right? And then have even more inflammation, which elicits a healing response, but it only elicits a healing response for like 48 hours. 15:04 Speaker 1: Then it's just slowing you down and not recovering. Okay. So, 15:09 Speaker 1: it's skipping is not a bad idea to take on a regular, like, 15:13 Speaker 1: like a maintenance 15:15 Speaker 1: protocol. If you're, if you're working your ass off, 15:18 Speaker 1: if you're doing kind of too much physical activity, 15:21 Speaker 1: great. That will help a lot. Any autoimmune conditions and like you just said, the post antibiotic 15:29 Speaker 1: uses. So if you went through a cycle of antibiotics, 15:32 Speaker 1: run some KPV. Run 15:34 Speaker 1: Run it. This. You know what I mean? What? Got gut inflammation, 15:39 Speaker 0: IBS, 15:40 Speaker 0: helps support gut lining. What else? Bloating, 15:44 Speaker 0: digestion 15:45 Speaker 0: issues. I mean, how many people have that for countless different areas? I mean, again, the food that we eat is just 15:54 Speaker 0: causing a lot of problems. So it's great. I think everybody listening to this is probably going down. I need to get some of that stuff. Yeah. I'll leave you with 1 last anecdote. No doubt. My, 16:03 Speaker 1: well, 1st of all, do want to talk about, cortisol. 16:06 Speaker 1: Cortisol. 16:07 Speaker 1: I think we all know cortisol. It's in commercials for women's products. Oh, bad. You know, get rid of the bad cortisol. Cortisol is our, 16:15 Speaker 1: is our, is the hormone that goes off essentially that from a fight or flight response, right? So anytime 16:22 Speaker 1: stressed, 16:24 Speaker 1: we that elicits a fight or flight response in us in this stress response. Okay? And think of it this way, guys, we are all cavemen still our body genetically, 16:33 Speaker 1: you know, it takes a lot of evolution does its time, but it takes a while. 16:37 Speaker 1: So we 16:38 Speaker 1: are what happens to our body when we're in this, in this fear response, our body just start thinks it thinks we're going to have no food. We need to use a lot of energy. 16:48 Speaker 1: We 16:49 Speaker 1: basically need to be in a cave and we have to fight off a bear for 3 days with no food and heat. Okay. So what it does is it just starts, 16:57 Speaker 1: it starts storing fat. So any little bit of food you can have, you eat, it'll store it as fat. It will start actively breaking your muscle down and turning it into sugar, filling your blood with sugar to give you energy 17:09 Speaker 1: right now to go do the necessary task to essentially like keep you alive, right? Any of that energy that you do not use, it tears your muscles down, fills it with sugar. If you don't use that energy, it goes great. Let's store this as fat because who knows how long we're gonna have to be here working 17:24 Speaker 1: hard. 17:25 Speaker 1: And, and actually, and we know this, like all of that, that cortisol fat is stored right by your belly button, right? That's your lower belly is where all that fat works. Now, a lot of things can elicit this response. So like you said, no sleep, Like, sorry, if you just slept less than like 5 hours, guess what? All day long. 1st of all, you didn't build, 17:45 Speaker 1: didn't build any muscle while you're sleeping. You didn't burn any fat while you're sleeping. You're not losing weight. 17:51 Speaker 1: We have a lot, if we actually get a good night's sleep, you will people, I mean, I sweat when I sleep because my metabolism is just revved and I'm burning tons of calories. 17:59 Speaker 1: My body's rebuilding all of its muscle, right? And is burning a lot of fat. But if you have low sleep all day long guys, guess what? Your body is not burning any fat. You're in this cortisol cortisol response, right? Your body's actively breaking muscle down 18:13 Speaker 1: and storing fat. If you drink alcohol, alcohol is poisoned, folks. That immediately 18:19 Speaker 1: elicits the same response and alcohol burns off, you know, maybe 2, 3PM the next day, you know? So that entire time your 18:28 Speaker 1: body is not burning fat and is not building muscles and it is just basically 18:31 Speaker 1: creating 18:32 Speaker 1: fat. 18:33 Speaker 1: That's why you get, it's usually why you get fat from drinking plus your inhibitions for good, healthy food and decision making goes down. Was gonna say that word. So 18:41 Speaker 0: you're tired and you feel like shit and like, you know, like cortisol high and like, you're like, even if you don't even know what's happening, which most don't in their body, like, the hell? 18:50 Speaker 0: You make poor decisions, man. When you're tired, I do. When I'm tired of my dude, I'm not eating my steak and eggs. Dude, I want some like Doritos and shit. You know what mean? Like, that just sounds better. You know what mean? We make poor decisions when we're tired. You know what I mean? It's so funny, dude. Absolutely. And then also like any, so, so he said low sleep stress, 19:12 Speaker 1: traveling. 19:14 Speaker 1: Like, I don't know if you've, for people who travel a lot, that sucks. I'm sorry, but your body isn't always in this, you know, it's circadian rhythm is messed up. It's always in this kind of stress state. Anybody who's going through a breakup with a significant other, These big stressful events in our life, like you'll notice that that's when people get out of shape or don't for sure as hell don't make a bunch of physical progress just because you can't, your body is just not burning fat and not recovering as it should. So consistency 19:40 Speaker 1: is key that ever you I mean, there's a whole bunch of lifestyle changes that we talk about all the time that can keep you out of that response, but also, 19:48 Speaker 1: a ton of peptides that help help with this also 19:52 Speaker 1: to keep you out of there and to combat it. 19:54 Speaker 0: I mean, think about it now because peptides have made such, you know, are making such waves and so many people are taking them and falling in love with them rightfully so. 20:03 Speaker 0: Gosh, think about 10 years ago when really nobody heard about them and these people were going through the same stuff. So at least we have these types of things because, 20:11 Speaker 0: you know, I speak with experience when you're going through something and you go to a doctor, 20:16 Speaker 0: you know, 20:17 Speaker 0: what's their response 20:19 Speaker 0: almost always is here, here's some antibiotics. I've had doctors tell me what I have. My autoimmune can't be cured, but take some antibiotics. Well, why the hell would I do that? Like, if it can't be cured, then why am I doing that? My problems with my gut, you know, and like, why am I telling you this? You know what I mean? But, that's what they know. So they're going to give you these antibiotics. 20:38 Speaker 0: So if that's 20:39 Speaker 0: somebody that's dealing with something like that now, like you can have, you can start with KPV and you can start with BPC and you can do these things at least 1st and start fighting it and 20:51 Speaker 0: not necessarily go the Western medicine route, because regardless of what your stance is on that, I don't care. It's not the point of what I'm talking about. 20:58 Speaker 0: You know, like they're going to jack you up. Antibiotics, 21:01 Speaker 0: they fixed like a little problem here, but there's 17 chain reactions that a lot of times don't show up for months, years, and that's autoimmune. You know what I mean? So if we can kind of step away from that and just start to use peptides, which are just chains of amino acids, dude, 21:19 Speaker 0: that's a healthier lifestyle, dude. And then when you need, when you really, really need the antibiotics to work, they just won't work if you build immunity. Cause we know we can easily build immunity to them. 21:31 Speaker 0: So yes, don't use them if you can't. So yeah, everybody, 21:34 Speaker 0: go out and get some KPV. KPV. My 21:37 Speaker 1: last thing is 21:38 Speaker 1: anecdotal like story. So like my girlfriend, for example, she was having, I've said this before, was having like gut, like what's what sounded to me like heartburn issues, except for she wasn't experiencing it up where a heartburn occurs. Right? It was like it was a lot lower. 21:54 Speaker 1: And the 21:56 Speaker 1: only response that I had was, it's probably this you're starting of leaky gut, right? This is what starting of an ulcer is when our mucus lining of our stomachs, we have our stomach acid mucus 22:07 Speaker 1: lining over that. That gets, when the mucus lining starts to get burned through with our stomach acid and this acid touches the actual stomach wall, 22:16 Speaker 1: that hurts like hell. And it is like, it well, it feels like acid, right? Except for it's not reflux. It's not going up the tube. It's actually kind of going out the side of the stomach. So she did a heavy course of KPV 22:29 Speaker 1: and 22:31 Speaker 1: BPC 22:32 Speaker 1: as well. And I was talking to her yesterday and she's like, I have no pain 22:36 Speaker 1: like whatsoever. That's right. Healed. Now she needs to keep doing. She also, what she also did was lower her caffeine, her coffee intake, 22:44 Speaker 1: right? Cause that's just pouring acid down in there. 22:47 Speaker 1: So she did some other lifestyle changes as well, but yeah, 22:52 Speaker 0: dude, that's a good point, dude. That's a good point. Cause we're talking about peptides and that's the focus of this podcast obviously, but, you know, we do tap on this a lot, but there is a lifestyle change. If you're going through some type of problem in the peptide, let's focus on whatever peptide, hypothetically peptide fixes that. There's so many other things that you need to do, like diet changes, 23:13 Speaker 0: obviously exercising, 23:14 Speaker 0: get moving. You need, if you, I hope, to God people do research this and dig into these things because it's not just the peptides, 23:21 Speaker 0: it's, you know, we've said it about hormone replacement 1000000 times that the peptides are only going to work well if you're optimized 23:27 Speaker 0: hormonally. 23:28 Speaker 0: Like, it's, there's so many things and like, dude, I'm living proof of just some of the stuff I've recently gone through and I was blown away by it. It's not like I think I'm a pretty healthy dude, but I'm going to be 49 in a month. And 23:40 Speaker 0: for years I abused my body and I put it through hell and back and there's residual, man. There's just, there's, it's unavoidable. I took a lot of painkillers at 1 time and I jacked up my gut and I'm paying for it. You know what I mean? Later on in life, it is what it is. But, you know, I'm taking those, those, 23:58 Speaker 0: I'm doing what I can do working with Doctor. Scott, you know, stool tests, all those things to fix this stuff, man. All of us. It's important because every single 1 of us should want to 24:08 Speaker 0: obviously feel good 24:10 Speaker 0: and the best that we can do. And that takes work, man. 24:14 Speaker 1: Does. It takes work. It takes consistency too. Does. 24:18 Speaker 0: Figure 24:19 Speaker 0: out why, right? If you're off and you don't, because I think, I think Americans 24:24 Speaker 0: in general 24:25 Speaker 0: have gotten so used to kind of feeling like shit because we have such bad diets. Are most people, right? They just eat poop food, dude. And like, I think you start just like, you think that's the norm. And when you can start to back that off and heal yourself, 24:43 Speaker 0: you can go, Dude, I feel like 1000000 bucks. 24:45 Speaker 0: That's how we're supposed to feel. It doesn't matter how old you are. We're supposed to feel good. We 24:50 Speaker 1: are supposed to feel good. And 24:53 Speaker 1: like making these changes, here's what I see a lot is people, 24:56 Speaker 1: okay, I feel bad. Oh, let's make a change. They try something for like a day or 25:02 Speaker 1: once or instant gratification. They're like, Oh, doesn't work. Doesn't work. Screw it. I'm not going do that again. Like, dude, you need it. And maybe it didn't work. Hey, maybe you do it for something like 3 weeks a month. Okay. It didn't work. And now it's not time. Well, I 25:15 Speaker 1: just can't be, just can't be fixed. No, that's, that is data. That's good. You kind of sometimes need to know what doesn't work before you figure out what does work. Okay. So 25:25 Speaker 1: good job, but keep persisting. 25:29 Speaker 0: Look at it like this. Watch this, folks. Didn't gain all this weight overnight, so you're not going to fix it overnight. It's 25:36 Speaker 0: going to take time. You gained weight over a long period, right? So give yourself some time to 25:41 Speaker 0: rectify the boat. 25:43 Speaker 0: Oh shit. 25:45 Speaker 1: Yes. You and Matt, we want it fixed now. We 25:48 Speaker 1: want to fix it now. We're all the same. We all are the same. Cool. KPV, awesome dude. Let's talk about the fun 1 that, 25:56 Speaker 0: if you are listening to this and you have not heard about PT-one hundred 41, 26:01 Speaker 0: you're gonna love this because it is definitely 26:03 Speaker 0: 1 of my favorites, at least for fun. I mean, I don't, I don't have a erectile dysfunction or any problems with arousal. I'm madly in love with my bride, but, every once in a while 26:15 Speaker 0: it's just good to take it, man. And like, it does help with arousal. 26:18 Speaker 0: And so tell us a little bit about 26:20 Speaker 1: Okay. So we had talked about this. Well, so 1st of all, how did this thing get discovered? So in the eighties, that university of Arizona, 26:28 Speaker 1: they were studying, 26:29 Speaker 1: drugs, peptides specifically for tanning. Okay. They're doing tests on 26:34 Speaker 1: men and actually specifically on Melanotan II to see how well it worked to make them tan. Then 26:42 Speaker 1: they started getting 26:44 Speaker 1: all of these men started just getting spontaneous erections. 26:48 Speaker 1: And I said, what the hell? Why is this? Which then shifted the entire field, the entire research project to, okay, maybe let's now develop a libido drug. 26:58 Speaker 1: And this is what they came up Right? By the way, Melanotan II folks, if you take that, it has the same like amino acid chain PT-one hundred 41 does. So it will also make you a little bit horny and PT-one hundred 41 will overuse 27:12 Speaker 1: over long term use 27:14 Speaker 1: will affect the pigmentation of your skin. It will make you a little bit darker, not to the degree in as fast as MTN2, 27:21 Speaker 1: but it will. So 27:23 Speaker 1: then, so yeah, it is now, so as 2019, 27:27 Speaker 1: it was FDA approved for like post menopausal women with low libido. 27:32 Speaker 1: And the cool thing is it does not, it does not work like a Viagra Cialis. Okay. So it is not, those are just purely, Hey, let's pump blood to blood vessels where our body asks us to pump blood. Okay. So a lot of people have ED that is not fixed by Viagra Cialis. Imagine, 27:50 Speaker 1: I don't know, I guess that happens, but apparently that is happening. That happens. 27:54 Speaker 1: Their problem with their ED is 27:57 Speaker 1: a mental thing, right? They're just not getting turned on. So that's what this is purely a mental peptide, 28:04 Speaker 1: right? It just enhances 28:07 Speaker 1: your dopamine, which is what is our like desire and our motivation. 28:12 Speaker 1: And 28:13 Speaker 1: it will enhance that. So anything you start to kind of want more, it will make you really want it. 28:19 Speaker 0: And for some, and it worked really well with our sex drive really well. It really does. Mean, it's great to be incredible. I mean, 1 of, I think 1 of the things we come across 28:29 Speaker 0: very often is just women, menopause and stuff like that. You know, I mean, gals that go through a lot, but you know, if your sex drives off, if you're moody and you're probably your husband's bugging you and whatnot, 28:40 Speaker 0: this will work. It really will. You know, I know some people have like say that it doesn't work. I don't know what you're talking about because I'm telling you, it's a pretty powerful thing. And like Will said, it's not like a CLS where it's going to affect the blood flow. It's a, it works from your brain. So very different. I mean, very different in what they do. Similar results. Now, best part, 28:58 Speaker 0: CLS doesn't do anything for the ladies. 29:01 Speaker 0: BT-one 141 equally, equally as much in regards to arousal and stuff like that. And I know that for 29:08 Speaker 0: whatever reason, 29:09 Speaker 0: know, and it's coming around for hormone replacement for women and whatnot. We've seen such a big change. Thank God, even women get in on a small dose of 29:18 Speaker 0: testosterone, 29:19 Speaker 0: but let's say a woman doesn't even know about that and their sex drive probably sucks. This is at least going to help, you know, you take this 1 night, you're probably gonna like at least, you know, want to get some that night. It will, 29:31 Speaker 1: you know, fucking works, man. Like you have really worked. So I would say in like how, okay, here's, 29:37 Speaker 1: this is what everybody can expect. So I would take it like 45 minutes before the actual 29:43 Speaker 1: act of sex. It takes a bit to kick in when I do it. And what I do is like a 10 mg bottle. 29:49 Speaker 1: I add 2 mils of water and then at a higher dose for me is about is 20 units. So that's equals that. That means I'm injecting 1 mg. Okay. Anything 30:00 Speaker 1: less than 10 units, anything less than 0.5 a milligram, it's probably not going to do anything for me at all. 30:06 Speaker 1: I have done up to 40. I've done 2 mg. Okay. And it was way too much. You once I do the injection, I definitely get flush red. 30:15 Speaker 1: Right away. Right away to varying degrees. And then it and then it's it slowly builds in your system. 30:24 Speaker 1: And it's, what's funny is like, don't really start going, gosh, I'm just super horny. But as soon as you maybe like touch your girlfriend or start kissing her, then it's like, oh my goodness. 30:34 Speaker 1: And then during the act it makes you hypersensitive 30:38 Speaker 1: and 30:38 Speaker 1: really into it, I guess. Yeah. But you can, but it will at the same time, nausea and so it can make people nauseous. Don't really get nauseous. Like it doesn't make me want to throw up. What I do 30:49 Speaker 1: feel almost is like slightly almost like hypertensive, 30:54 Speaker 1: But I got to find the right dose and that's if I do too much, right? Like, it can make me feel like crap. 31:00 Speaker 1: It can increase your blood pressure, 31:02 Speaker 1: folks, for some people, especially at higher, higher doses. 31:07 Speaker 1: But, you know, finding the right mix, I would say women, 31:10 Speaker 1: I think you should be doing 31:12 Speaker 1: If I'm a man and I'm going do 1 mg, I'd say, well, I'm going to start with 0.5 a milligram to maybe 0.75 of a milligram. 31:19 Speaker 1: Just a smaller body. I'm a big body. Maybe I can take more. The clinical dose like the FDA approved dose for postmenopausal 31:26 Speaker 1: women is a 1.75 31:28 Speaker 1: mg, which strikes me as like, that's crazy. That's high. So I don't know. Maybe they're maybe they're PT-one hundred 41 they had isn't very good, but let's get these girls corn that I use is, 31:40 Speaker 1: that's a lot too much. 31:43 Speaker 1: So it 31:44 Speaker 1: also is very stable. So it's, 31:47 Speaker 1: I've had open bottles of PT-one hundred 41 for 31:51 Speaker 1: 7, 8 months. They are not even in my fridge. 31:55 Speaker 1: It's still work. Yeah, for sure. And you use them as needed, right? I don't, you know, you don't, it's just as needed. I know that at 1 point you were experimenting, taking 32:03 Speaker 0: a little mixture of of of a very low dose of PT-one hundred 41 and oxytocin in the morning, just no matter what. Because I was reading about a lot of people that are starting to like microdose it on a daily basis, kind of like how people might microdose Cialis. 32:17 Speaker 1: So 32:19 Speaker 0: I was doing it for a while. I mean, because the 1 thing about that I've experienced with it is similar 32:24 Speaker 0: effects to like a Cialis to where for me, I don't have any erectile dysfunction type stuff. So it works for days after. Not so like intense as the 1st day, right? But like, you know, you kind of feel, I was telling him before this, like, so I take about the same. Take, I do 1 mg or 1 mil of water. He does 2, but then he does 20 units and I do 10. So it's the same math. It's a milligram. And that's generally the sweet spot I have, but you know, me just being me and just wanting to test the limits. So I did 20 units of that. So 2 mg 1 day and it was great sex, you know, it was an intense night. 33:02 Speaker 0: But the next day, you know, I was like a 16 year old dude. We did a podcast and I'm like, you know, all day long, like a 16 year old, I'm like, Oh man, it's just too much, dude. I don't want to be like that. You know what mean? I got stuff to do. So, 33:16 Speaker 1: 1 time, 1 time I gave myself twice as much. I forgot. I messed up and forgot 33:22 Speaker 1: that I only put 1 milli water in. And so then I did 20 units. Right. And then I gave my girlfriend similar to that and it was too much and we both felt like crap and she's like not wanting to take it ever since. Oh, really? Because 33:34 Speaker 1: it was a lot. Was way too much. But I also, it worked, but we were in Palm Springs and yeah, 33:40 Speaker 1: I like couldn't really like leave the pool, but, and I did not feel good, but it worked. It worked really In 33:46 Speaker 0: the beginning of, 33:48 Speaker 0: like peptides and whatnot, I would have my stack and I would have Alyssa with her stack and my wife, she's come a long way and knows a lot about peptides for obvious reasons at this point. But in the beginning it was just like, she just, I would load her up and just give her what, and she took whatever I told her to take. She knew that I knew what I was talking about. I would give her sometimes a little bit of PT-one hundred 41 and we would have sex and it was great. And, 34:11 Speaker 0: you know, then she realized that that's what it was. And like, she'd bought, did you give me that stuff? I could tell. 34:17 Speaker 0: I did. 34:20 Speaker 0: Know Alyssa, dude, she's so funny. Yeah. So 34:23 Speaker 0: if you're ever going on a trip, like you're on vacation with obviously without the kids probably, but, man, it works well. You know, you'd like Will said, that's the cool thing about it is people think about like losing, 34:36 Speaker 0: efficacy and all that stuff. I've had it in my fridge for man, a long time and I hadn't used it for a long time and I used it. We're the exact same. 34:44 Speaker 0: We're the exact same. Yep. We're just saying it works. That's why 34:47 Speaker 1: it's so it can be used. It can be made into a nasal spray, and 34:51 Speaker 1: be shipped in last- Have you done the nasal spray? I haven't used it yet. I have. Yes, I have. And it's a bit, know, obviously, hey, look, the subcu injections are just, it's going to work better. You're giving yourself more of a concentrated dose. 35:04 Speaker 1: It's more of an exact dose also, right? And the nasal spray sometimes you spray 35:08 Speaker 1: like it gives you 0.5 of a spray and it's hard to quantify that. The they work the same. I mean, it's the same result. I think that the nasal spray is you can give yourself a smaller gentle dose, I suppose. And 35:22 Speaker 1: I don't care either way. So or you can just, you know, exactly how much you're giving yourself 35:27 Speaker 1: and do it right with the injection. I don't think I don't notice there's no difference in effect. 35:32 Speaker 1: Yeah. It's just personal preference. Doesn't really Each his own, man. Another use, like, you know, you go to a party and you just, like, bring a couple bottles of that and, like, spray it into the punch, 35:42 Speaker 1: for everybody at the party. 35:44 Speaker 0: It's so hot in here. Don't 35:47 Speaker 1: do that actually because there might be some people who have like allergic reaction. So don't do that folks, but I thought it'd be funny. I actually just told a story to somebody about this doctor that did that, but with Viagra, 35:57 Speaker 0: I think that's brilliant. He did? Like, is that real? Yeah, 36:01 Speaker 1: real. Like crushed up like 100 Viagras into fine powder and just like poured them into the punch bowl at the party. 36:07 Speaker 1: I doc. 36:09 Speaker 1: I know. 36:10 Speaker 1: You are a doctor. Same type of people who like same type of doctors 36:14 Speaker 1: who've who are like, oh, they have those injector, the the like, 36:18 Speaker 1: erection injectors. 36:19 Speaker 1: Right? They just straight up in there and just inject it. That's 36:24 Speaker 1: where you run the risk of having a erection for lasting longer than 12 hours. Go see your doctor. 36:30 Speaker 1: Anyway, PT-one hundred 41, man, it works. Get your doses down, try it, you know, let's just maybe start with 0.5 a mg. 36:39 Speaker 1: You don't, you can always do a little bit more, right? You can start it 45 minutes later. Oh, let's add, let's give myself 10 more units, I don't really feel it. Right? And you'll people, you'll feel it. You'll notice what happens when you do 10 more than that. 36:53 Speaker 1: There will be a point to like, hey, I'll hold too much. Nausea, 36:56 Speaker 0: like Yeah. About maybe, like, 36:59 Speaker 0: 5 minutes later, it'll just like, it's a quick And 37:03 Speaker 0: then I just get through. Know it's there because it always happens. 37:05 Speaker 0: And then it just passes quick, but I do every time I get a little quick wave of nausea. 37:10 Speaker 1: Yeah, interesting. I mean, it's same thing. Like, it's funny, like, all they're all derived from 37:15 Speaker 1: from this Alpha MSH. And right? What do we know about Melanotan II? Like, it makes me nauseous. 37:20 Speaker 1: Every time. I can't I Melanotan II, there's I cannot there's no way I'm not taking that during the day. It'll ruin my day. I'll be nauseous all day long, even a tiny little dose. 37:30 Speaker 1: So Melanotan 1 does not do that. But even though if I were to you do them, I would definitely do them right before I go to sleep. 37:37 Speaker 0: So if there is nausea, I'm sick for it. It's been a while since I've done that. Long 10. But yeah, man, PT-one hundred 41 works. It works right now and it does. Yeah. If you're having some problems in your marriage, maybe try a little bit of this. Sex always helps it out a little bit. You know what I mean? But 37:54 Speaker 0: those are great, man. I think those are 2 great peptides. I thought those are, would be fun to do together. 37:59 Speaker 0: So 38:00 Speaker 0: awesome dude. I know, 38:02 Speaker 0: you come back on Sunday. 38:03 Speaker 1: I'll be back Sunday night. Yep. Back on Sunday. So let's 38:07 Speaker 0: let, 38:08 Speaker 0: we'll get back to his wedding. 38:10 Speaker 0: Make sure you join us on school. 38:13 Speaker 0: That's growing quickly and we got a cool stuff that we're about to drop for the VIP. 38:18 Speaker 0: So jump on there and we're gonna exclusively 38:21 Speaker 0: give content 38:22 Speaker 0: for just the people on the VIP. So we are improving it 38:27 Speaker 0: constantly. 38:28 Speaker 1: We are. We're working hard to improve it, put new stuff out all the time. Yep. 38:32 Speaker 0: Cool buddy. We'll get some rest. 38:34 Speaker 0: Enjoy your trip. We got the, we got the rock here. We're, doing good and, enjoy your trip and, we'll talk to you soon, man. Cool, man. Thank you. Take care, buddy. All right. All right, man. Later.