Peptide of the Week: Kisspeptin + Oxytocin – Hormone Balance, Libido & Love Drug Effects Peptide of the Week https://peptideoftheweekpod.com/episodes/peptide-of-the-week-kisspeptin-oxytocin-hormone-balance-libido-love-drug-effects/transcript We are not doctors. The content on this site is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Amounts, timing and cycle lengths below are reported as the named speaker described them. Nothing here is a protocol to follow. --- 0:09 Speaker 0: Welcome back to the Peptide of the Week Podcast. 0:12 Speaker 0: I'm your host, JD Denham, as always, my man, my brother, 0:16 Speaker 0: my friend, my cohost, William T. Haws, probably. What's up, dude? What's up, my man? Good to be here. Was funny, man. I 0:25 Speaker 0: was talking about this on my other podcast. I was thinking, man, and it's crazy how 0:30 Speaker 0: Christmas is in 2 months, dude. Christmas is in 2 months, bro. Like, it just seems like it was just January, you know? Like, I remember thinking it was January, like, with the whole year ahead of us, and it's like, dude, we are almost done with the year. 0:43 Speaker 1: Know. It's going fast, man. Hey, every year, the older you get to, time flies. 0:48 Speaker 0: I don't know if that's the case, man. Remember? Yeah. I always, like, kinda resort back to, like, high school. Do you remember 4 years in high school? I was like, dude, this takes forever, dude. Like, what the hell? 0:57 Speaker 0: You get out and it's like rocket ship. 0:59 Speaker 1: Crazy. Sometimes the minute it's like sometimes, right, the minutes are slow, the hours are slow, 1:06 Speaker 1: but the months and years are fast. 1:08 Speaker 0: Blinking is done. Right? Yeah. 1:11 Speaker 1: I don't know. It's probably because we 1:13 Speaker 1: as you get older, you just have more on your plate, dude. You just got more on your plate and you go, 1:17 Speaker 1: then just try to get everything done all the time. Before you know it, time is gone. 1:23 Speaker 0: Busy is the good thing, man. I'll take busy over slow any day. Yeah. 1:27 Speaker 0: Any day. Well, today is an exciting day. 1:31 Speaker 0: I love what we do, man. I love this. I love I geek out on this. I love talking about it. I love just digging into this stuff. I'm so intrigued by all this stuff. So today 1:40 Speaker 0: we're going to talk about 2 different peptides. We're going to talk about Kisspeptin, 1:44 Speaker 0: which is, I think everybody that's going to listen to this 1 are going to enjoy it. 1:48 Speaker 0: With some of the things going on in the world with men's testosterone, 1:51 Speaker 0: blah, blah, blah. 1:53 Speaker 0: It's Peptin's awesome. 1:54 Speaker 0: And then we're going to talk about the love drug oxytocin. 1:58 Speaker 0: So, 1:59 Speaker 0: yeah, 2:00 Speaker 0: these are going to be good, dude. So let's start with the Kisspeptin because 2:04 Speaker 0: why not? 2:07 Speaker 0: Not? 2:08 Speaker 0: Tell us, Will, and we'll dig into this because I think there's a lot going on with this peptide in general that we can discuss. 2:15 Speaker 0: But as always, I'll throw it to you. Tell us a little bit about what it is, what it does, why we should take it. 2:22 Speaker 1: So, 2:24 Speaker 1: I guess what people are, if we're talking about taking it, right, you're looking for Kisspeptin-54. 2:30 Speaker 1: Okay? It's 54 amino acids. There is a 2:34 Speaker 1: different form out there like Kisspeptin-ten, 2:37 Speaker 1: which 2:38 Speaker 1: is a shortened version, 2:40 Speaker 1: but 54 is what 2:42 Speaker 1: people should be looking for. It's what's naturally in our body. 2:46 Speaker 1: It 2:48 Speaker 1: so Kisspeptin 2:49 Speaker 1: is, I guess, in men is really 2:52 Speaker 1: main goal is to deal with our testosterone and reproductive 2:56 Speaker 1: health. 2:59 Speaker 1: It basically the quick sign that we got an answer to is 3:02 Speaker 1: it stimulates your pituitary 3:04 Speaker 1: gland in your brain, 3:07 Speaker 1: which then 3:08 Speaker 1: signals out down to your testes to 3:11 Speaker 1: increase your luteinizing hormone, which now makes 3:15 Speaker 1: testosterone. 3:16 Speaker 0: Right? 3:17 Speaker 1: Huge. And sperm and etc, right? 3:22 Speaker 1: That is how and that's the natural process. So basically, just like think of it this way, it kicks off the actual natural process. A lot of people are familiar with HCG. 3:32 Speaker 1: Right? Men are from doing, like, post cycles 3:36 Speaker 1: and 3:38 Speaker 1: trying to be fertile. So HCG 3:41 Speaker 1: just is a LH mimetic, so luteinizing hormone mimetic, 3:46 Speaker 1: which basically is only so it 3:49 Speaker 1: just does 1 thing at the very end of that cycle, okay? It just tells the luteinizing hormone, Let's go. Let's make more right now, right? Whereas Kisspeptin kind of kicks off the whole reaction naturally, 4:00 Speaker 1: if that makes sense. 4:03 Speaker 1: But 4:04 Speaker 1: it's cool. It's being researched for a whole lot of things and 4:08 Speaker 1: some of the main research findings really are helping men with feelings of desire and increased libido. 4:15 Speaker 0: So 4:16 Speaker 1: daily doses and really, 4:18 Speaker 1: yeah, feeling more horny, I guess, all the time. 4:21 Speaker 1: And your research is coming back like very, very positive. 4:25 Speaker 1: With people I know and who have taken it, 4:28 Speaker 1: it's working. I know that. You even have some experience on 4:33 Speaker 1: taking it 4:34 Speaker 1: and it working. 4:35 Speaker 1: Yeah. It really worked because it produces some of the side effects that you know come along with testosterone increase. 4:42 Speaker 0: I mean, that's interesting. Let's talk about that because there probably would be some men like me, and I've discussed it on podcasts multiple times, but if you're new to the show, I've struggled. Everybody's different. 4:52 Speaker 0: Are all science projects. For some guys that I know, good friends of mine, they don't ever deal with gynecomastia 4:58 Speaker 0: from 4:59 Speaker 0: day 1 of taking testosterone. 5:01 Speaker 0: I mean, from the 1st shot, I struggled with gynecomastia. 5:06 Speaker 0: Testosterone 5:06 Speaker 0: converts to estrogen, and I'm just that guy. I've actually even had the surgery because when I was younger, even before the internet, it wasn't so freely available. 5:16 Speaker 0: I was not doing things properly. 5:18 Speaker 0: So I got a bad case of gyno and had eventually had it cut off. 5:22 Speaker 0: But for you guys out there that think after you have the surgery that it can't come back, you are wrong because I'm telling you, can. Will knows because Will's known me a long time and we've discussed this umpteen times. 5:35 Speaker 0: I just have struggled with it. So for whatever reason, I think that I've just kind of got a good grasp on it. I hadn't struggled with it for a very long time. 5:43 Speaker 0: When I was reading about Kisspeptin months ago, 5:46 Speaker 0: I was intrigued by it. I'm like, this sounds amazing. It increases your libido. 5:50 Speaker 0: It naturally brings up your testosterone without your own testosterone bringing it down. It's not like you're injecting testosterone. It just sounded great. So I want to try every peptide, so I did. 6:02 Speaker 0: And it's funny because 6:05 Speaker 0: a few months ago, I was even talking to Will. I was like, Dude, I'm out of nowhere getting freaking gyno again. Like, what the hell is going on? And I hadn't put it together yet. 6:15 Speaker 0: And I started pulling things out of my stack and lo and behold, it was a Kisspeptin. So for me, gentlemen, just so you know, 6:24 Speaker 0: it can increase my testosterone to the level that it started converting to estrogen 6:28 Speaker 0: and I was getting gyno again. 6:31 Speaker 0: Just be careful. 6:32 Speaker 0: Just be careful. That's just 1 of the negatives, but obviously the positives are huge. Now, 6:40 Speaker 0: Will and I have talked about this numerous times. We don't fully understand it, but everybody's different. We're big fans of each zone. For you people that do not want to run testosterone, 6:50 Speaker 0: that's on you. So if you want to not run testosterone, you're over 40, whatever, 6:56 Speaker 0: maybe try this. This will help your body to boost 7:01 Speaker 0: up your own testosterone levels. I don't think you're ever going to get what you would get if you just 7:07 Speaker 0: testosterone, but you can try. 7:09 Speaker 0: This would be a way that can help. So it can help your sperm production as well. Right. So I guess back on the testosterone, it's really interesting where 7:18 Speaker 1: HCG will 7:21 Speaker 1: boost a man's, like, they say, it's like secondary hypogonadism. 7:26 Speaker 1: Okay? So 7:27 Speaker 1: that basically means and not their primary high. So if they were born with low testosterone, HCG apparently is not going to do much to them. Now if they, 7:36 Speaker 1: through their own usual, like, steroid or excessive testosterone use, have lowered their natural testosterone output now, right, 7:44 Speaker 1: now HCG will 7:46 Speaker 1: help with that. That will help get them a bit higher to where they 7:52 Speaker 1: naturally should have been. 7:53 Speaker 1: But 7:54 Speaker 1: it's not going take them any higher than that. Anybody who, if you know, have normal testosterone and it's declining because of just natural reasons, generally, HCG isn't really going to help much at all. So that's why. 8:04 Speaker 1: But Kisspeptin 8:06 Speaker 1: will 8:07 Speaker 1: because it 8:09 Speaker 1: starts the entire natural process. Right? Yeah. Right, right, right. That So makes that is cool. So for anybody, yeah, suffering from low tests and doesn't want to actually try testosterone, 8:20 Speaker 1: I would try Kisspeptin. I'd also try probably Enclomiphene 8:25 Speaker 1: similar 8:26 Speaker 0: for 8:28 Speaker 1: and I guess the fertility portion. Yep. It's going to also increase your fertility. And, you know, everything is still being researched. This is a new 8:36 Speaker 1: peptide, 8:38 Speaker 1: and research is absolutely ongoing. But in that research, they have absolutely found 8:44 Speaker 1: a lot of people that it's increased their fertility. Not guaranteeing 8:48 Speaker 1: everything. Like, you're not gonna guarantee you're gonna make a baby just because you take this, but it's worth a try. 8:53 Speaker 1: Any help I is 8:55 Speaker 0: think in today's world, 8:58 Speaker 0: especially guys, we just have worked with a lot of men in regards to fitness and just coaching and personal training, blah, blah, blah. And we've seen it, men's testosterone levels have plummeted. 9:08 Speaker 0: We could go on and on about the why. 9:10 Speaker 0: We'll set it to the side because it's not important. It is what it is. 9:13 Speaker 0: So these are things that are going to help you. Fertility, the same thing. Fertility ratios are down in regards to people. So, I mean, that was the reason, that was the main reason I started taking it. I've talked about it numerous times. My bride wants to have another baby. I'm gonna leave that in God's hands, but I will do the things that I need to do to help that maybe happen. So that's why I was That was the main reason why I was taking the Kisspeptin months ago, 9:37 Speaker 0: because of the fertility. I mean, the cool thing about women, too, is it's gonna regulate estrogen and progesterone. 9:43 Speaker 0: So 9:44 Speaker 0: it really is just going to regulate hormone levels. 9:47 Speaker 0: I think it's going to really try to just really regulate those. 9:51 Speaker 0: And in today's world, I think in my opinion, for whatever that's worth, I think the food is just shaking up our hormones and just they're just all out of whack just because the food's injected with hormones and blah, blah, blah, blah, blah. So this is gonna help that for sure. Absolutely. And so that yes, you're right. That's cool. So men take it. It's gonna go help directly kind of create some more testosterone. 10:14 Speaker 1: Women, 10:15 Speaker 1: yes, it will 10:17 Speaker 1: create a little bit more testosterone. But really, 10:19 Speaker 1: you're taking it, what's cool is its main function for women now is to help just balance out your hormones, 10:27 Speaker 1: Which is perfect, right? I don't know any woman I've ever been with who hasn't talked about their hormones being out of balance. 10:34 Speaker 0: Right. Menstrual cycles. So it's going to regulate their menstrual cycle. Let's talk about that. I mean, it is what it is. We've dated a lot of women in our day, and I can't tell you 1 that hasn't talked about their menstrual cycle being out of whack. So this can help with that. It can help with that. And I think what we're going to talk about next, oxytocin, there's a little bit more evidence on that 1 really helping with that. But 10:54 Speaker 1: yes, balancing out your sex, 10:56 Speaker 1: woman's sex hormones, 10:59 Speaker 1: which is important. 11:00 Speaker 1: Boosting libido. So let's kind of sit on that for a little bit because who in the world wouldn't want that? You know what I mean? So 11:06 Speaker 1: for the people, which I don't fully understand this because 11:10 Speaker 1: I don't know, man. I mean, PT-one hundred 41 is amazing. 11:13 Speaker 1: We've talked about it numerous times, but we've also had a lot of people say that it doesn't work. So I don't really understand it. 11:19 Speaker 1: But if that's 1 of the people you can maybe try 11:22 Speaker 1: that peptide and maybe try this 1 as well, compound them and 11:27 Speaker 1: see if that because it's supposed to boost your libido, 11:30 Speaker 1: so maybe give both of them a try. Yeah. Why not? Yeah. Like I said, like the 11:36 Speaker 1: the most most conclusive research on Kisspeptin is really 11:41 Speaker 1: showing that it's going to help with sexual 11:44 Speaker 1: desire and libido. 11:46 Speaker 1: And take it on a daily basis, right? Take a small amount. I think the suggested 11:51 Speaker 1: dosage there is maybe like 300 to 500 micrograms 11:55 Speaker 1: a day. 11:56 Speaker 1: Subcutaneous works. 12:00 Speaker 1: Yeah, 12:01 Speaker 1: men and women. Yeah. 12:04 Speaker 0: Works the same. Yeah, it's, I mean, it's, I mean, the benefits behind it are huge. 12:10 Speaker 0: Yep, yep, yep. It's a priority because I don't, you don't hear that many people talk about it. I'm glad whoever would had mentioned this in the last Q and A, we appreciate it because I think we were talking about the Kisspeptin, but oxytocin, we were not. 12:22 Speaker 0: And these 2 just really run 12:24 Speaker 0: awesome together. There's a lot of similarities. Obviously, they work different, but it's a boost testosterone. 12:30 Speaker 0: It balances your hormones. It boosts your helps with fertility. 12:34 Speaker 0: It's going to help regulate women's 12:37 Speaker 0: progesterone and what is it, estrogen, which is huge. That's huge, man, in today's world. So for anybody listening, 12:45 Speaker 0: you ladies, this will help. Can bring down stress, too. I know that oxytocin is known to do that as well. 12:52 Speaker 0: We live in a stressful 12:54 Speaker 0: world, 12:55 Speaker 0: so why not? 12:57 Speaker 1: Right? Doctor. Yes, it is going to say it's going to bring down stress and happiness. 13:01 Speaker 1: I mean, I think thatbut we know that testosterone 13:04 Speaker 1: does that for a man, right? True. Look, if you start taking testosterone, 13:08 Speaker 1: you're going to be happier. 13:11 Speaker 1: The little things aren't going to stress you out as much. You're gonna sleep better, right? Just everything is everything is better and happier. So 13:19 Speaker 1: to be honest, I'm not quite sure in the Kisspeptin if it's because it's increasing your testosterone. Now all those good things, mental things are happening or- It makes sense. Yeah. 13:28 Speaker 1: Makes sense. Yeah, 13:30 Speaker 0: I mean, we've talked about it for guys that, 13:33 Speaker 0: gosh, man, for you men, dude, that are just like depressed and can't get out of bed and just, 13:38 Speaker 0: it's always testosterone levels, man. Your testosterone levels are just low, dude. It's very easy to see when a man's testosterone 13:44 Speaker 0: is low. Just that depressed 13:47 Speaker 0: feeling. 13:48 Speaker 0: Low testosterone, dude. 13:50 Speaker 1: Yeah. And it's a vicious it's a domino cycle. It's like, look, dude, less testosterone, the higher estrogen, okay? The more fat that you have. The more fat that you have, the higher estrogen you have and therefore it's bringing your testosterone down and harder to burn off that fat, right? You 14:05 Speaker 1: got fat because I eat and I eat because I'm fat, right? 14:08 Speaker 1: I mean, you know, 14:10 Speaker 1: there needs to be a fundamental 14:11 Speaker 1: change to change that, right? No wonder you can't burn the fat 14:16 Speaker 1: or add the muscle 14:18 Speaker 1: because your testosterone is low and because estrogen is high and that has been high because you have too much fat. 14:24 Speaker 0: So- 14:25 Speaker 0: In the cycle. 14:27 Speaker 0: You go in the gym, you're tired, but you're still making yourself go, you're not seeing the results so you give up. Simple fix, man. Get your testosterone levels up. Ding, ding, ding, ding, ding. 14:37 Speaker 0: Yep. 14:38 Speaker 1: Often, that's a simple fix. Right. So I guess the side effects, you mentioned that, but like really, 14:45 Speaker 1: side effects are so anybody who's if a man, if your testosterone increases, okay, our bodies like our normal ratio, which is this much testosterone, right, and this much estrogen, 14:54 Speaker 1: give or take, right? Some people have higher on the scale both ways, but everybody has their own ratio. Now, if we increase your testosterone, 15:02 Speaker 1: guess what? Your estrogen is gonna go try to find that same ratio, okay? If your testosterone raises 15:08 Speaker 1: a lot, then 15:09 Speaker 1: this estrogen is gonna raise a lot. And that difference in estrogen is all bad. Basically, that's what's gonna give you estrogenic side effects, okay? That's a good way to put that. That 15:18 Speaker 1: looks good. Those are water 15:21 Speaker 1: retention, 15:22 Speaker 1: nipples being sensitive, right? 15:25 Speaker 1: Any excess acne more like dotted out on your shoulders, etcetera, more oily skin. 15:31 Speaker 1: And those all can be cured by taking an 15:35 Speaker 1: AI, 15:37 Speaker 1: which most people call it an estrogen blocker. But Arimidex, 15:40 Speaker 1: Aromacin, 15:41 Speaker 1: Letrozole in 15:43 Speaker 1: harsh cases, but I wouldn't really assume that. So 15:47 Speaker 1: if you're feeling any of those symptoms while taking Estrozole will just completely shut the estrogen 15:53 Speaker 0: off, though. So if you're talking to right. If you're comparing yeah, 15:57 Speaker 0: it'll just kind of shut that estrogen down. So if your estrogen is extremely high, you can take the letrozole and it will shut it completely down. But the Rimidex 16:04 Speaker 0: is more where it's just gonna kinda try to keep it a little bit more balanced. 16:09 Speaker 1: Yes. You would have put that, you know? Yeah, yeah, yeah. Arimidex is the weakest, and I shouldn't say weakest isn't a bad thing. Like, that's what every doctor's going to prescribe. That is- Sure. Because there is absolutely such a thing as just killing off too much estrogen. 16:23 Speaker 1: Aromacin is like is the it's not the harshest, but it is kind of the best. It is the suicidal. So it just basically goes in and just tries to kill kill off everything. 16:32 Speaker 1: And 16:34 Speaker 1: but I would start everybody with Arimidex 16:37 Speaker 1: because you don't wanna kill off all of your testosterone. 16:39 Speaker 1: If you do, you will have no sex drive at all. Yeah, 16:44 Speaker 0: that would, like, at all. Why I taking joints hurting? 16:47 Speaker 1: Your joints hurt. Your cardiovascular system isn't as good. You'll start getting winded if you walk upstairs. Your joints hurt because you have no estrogen and your body's purging all the water, you might look great. You might look super lean, but you're losing like even lubrication in your joints. 17:03 Speaker 1: So and if you've done this, I don't know if you ask me or you, like, it's easy to tell. I could just tell 100% if my estrogen is too high or too low. 100%, yeah. And the goal is to take as little of the pills as you possibly can. 17:17 Speaker 1: Acidrogen blockers or aromatase inhibitors, 17:19 Speaker 1: AI, 17:20 Speaker 1: are pills usually. 17:22 Speaker 1: They make them in liquid, but whatever. 17:25 Speaker 1: Take as little of those as possible yet still see no side effects. 17:28 Speaker 1: And everybody 17:29 Speaker 1: is different. Can't just say, Go take this many pills and it'll work. Beats me. You've got to try. 17:35 Speaker 1: I would say take 17:38 Speaker 1: Take them until you level out, symptoms are gone, 17:41 Speaker 1: stabilize 2 weeks, then drop a little bit, incrementally lower your dose, see how you do. If symptoms come back, then oops, last week bumped back up to what I was last week, that's probably your sweet spot. 17:54 Speaker 0: Yep. Yeah, I mean, obviously 17:56 Speaker 0: the best is to not run Arimidex or anything like that, right? Is funny because I mean, 1st off, if you find a doctor that prescribes you testosterone, good on you because a lot don't. So that's rad. What I have seen with a lot of people where 18:10 Speaker 0: they start breaking out and their doctor doesn't even know that's probably estrogen, which is crazy because we know that. And that can be simply fixed by Rimadex. 18:18 Speaker 0: But 18:20 Speaker 0: again, like using myself as an example, when I've struggled with that forever, 18:25 Speaker 0: and I just have it down. Don't struggle with it. I don't take Rimadex at all anymore. 18:30 Speaker 0: 180 mg generally is where if I go above that, I do. So I'm just good with that. You know what I mean? So it takes a while to kind of find that. But again, 18:40 Speaker 0: I don't need to take it, so I don't take it. But a lot of doctors prescribe it and don't, they prescribe it where you don't you shouldn't just take it. Should 18:49 Speaker 1: take it if you need it. You know what I mean? So- Well, absolutely. You should not take I have taken it too early just when this was early on. Right? Like, if your estrogen is in check and now you take it, it's gonna kill off your estrogen, okay? And now it's gonna be too low and so your body's going, Shit, I don't have enough. Now it's gonna start trying to produce even more and you've just 19:09 Speaker 1: this whole plan has just backfired on you. Yeah. Because now your body's going hyperactive 19:14 Speaker 1: of producing 19:15 Speaker 1: estrogen. 19:16 Speaker 1: I've heard that happened to me. 19:19 Speaker 0: Is kind of like, 19:21 Speaker 0: to be example, guys, like the reason we know this stuff, because we've done it for a long time and it's gonna take a while to learn your body. It's gonna take a while. It just is what it is. Trust me. It's worth it. When you can get your hormones 19:35 Speaker 0: optimized, 19:36 Speaker 0: meaning running at the best you at the running at the best levels for you, Your energy is the best. Your sex drive is the best. 19:46 Speaker 0: That's what you're trying to get. Now, also, when you get there, 19:49 Speaker 0: the peptides work better. They'll still work, but like when you are hormonally optimized, meaning you find your sweet spot, which is radically different for everybody, 19:58 Speaker 0: you're optimized. You are where kind of God wants you, so to speak. Good way to say that. And then the peptide just enhance it all. Yeah. And it takes a while to get there. It just does. We've done it for a long time, and it took me a long time to find it. Is what it is. It's worth it. For sure. 20:12 Speaker 1: It's worth it. That's 20:14 Speaker 1: good, I guess. Yeah, man. Can talk to that stuff forever, man. Yeah, right. I could go on and all Forever and ever. Of the Serms and all the other side effects that potentially come along with any, like, AES use, but maybe for another day 20:28 Speaker 1: and how to tell, etcetera. 20:31 Speaker 1: I guess the last part is dosing 20:34 Speaker 1: on this thing. So 20:35 Speaker 1: generally, 20:37 Speaker 1: personally, 20:39 Speaker 1: I would do about 300 to 500 micrograms of Kisspeptin 20:43 Speaker 1: daily for 20:44 Speaker 1: the libido 20:46 Speaker 1: and 20:49 Speaker 1: mood and sexual desire. 20:51 Speaker 1: Maybe women do about 300, men 500. 20:54 Speaker 1: If I'm 20:55 Speaker 1: trying to make a baby, I'm gonna aim for 800 micrograms daily. 20:59 Speaker 0: Right. Generally, 21:02 Speaker 1: come in 10 mg bottles, 21:05 Speaker 1: which is 10000 21:06 Speaker 1: micrograms, 21:07 Speaker 1: okay? 21:09 Speaker 1: So we're aiming for, you know, 500 21:12 Speaker 1: to 800 21:13 Speaker 1: micrograms. 21:16 Speaker 1: Hopefully, you all can do the math on that. 21:19 Speaker 1: Maybe? 21:20 Speaker 0: Sounds good. Also, we have the the Peptide Institute research website that you guys can go to that we recommend to most people. 21:29 Speaker 0: Cool, man. That's a good 1. So, yeah, as as we said, 21:33 Speaker 0: that's a cool peptide. There's a lot. There's a lot. So if you are compounding it on top of testosterone, you might have the same problems as me. If you're not taking testosterone, 21:42 Speaker 1: I mean, you might not. Whatever. Depends on what you're taking it for, but does a lot, so give it a try. Okay. I also wanna state this, like, right, for all I know I've known JD for a while and, like, know that he's had a fitness channel and 21:54 Speaker 1: seen all the haters saying like, Oh my God, how much steroids do you do? Right? 21:59 Speaker 1: Like, I know he 22:01 Speaker 1: has estrogen issues and like literally cannot do more than 180 mg of testosterone. But we haven't forever. Which 22:08 Speaker 1: is pretty much a tiny amount. 22:11 Speaker 1: So for all of you who think that 22:14 Speaker 1: that's not hard work, it is. 22:16 Speaker 1: Doctor. Discipline. 22:18 Speaker 1: Doctor. Well, testosterone just helps a little bit. 22:21 Speaker 1: It helps a 22:23 Speaker 1: lot, but not in his physique because it's not taking a whole bunch. Generally, like the low smallest, 22:27 Speaker 1: the anabolic threshold is about 400 mg a week. At that, now it's really helping to build muscle. 22:35 Speaker 1: Being less than that, it's really it's boosting 22:38 Speaker 1: metabolism, 22:39 Speaker 1: helping you keep muscle, helping libido 22:42 Speaker 1: and brain fog and sleep, etcetera, 22:44 Speaker 1: helping you feel better, but not really 22:47 Speaker 1: helping out with the physique a bunch. 22:49 Speaker 0: Yeah, I mean, the key, I think, for everybody is 22:52 Speaker 0: feeling good, man, right? Like just keeping your energy level all day. 22:57 Speaker 0: That's what I seek at least, you know, where you have those crashes 23:01 Speaker 0: and it takes a little messing around with the numbers to figure it out though. I wish I could do more testosterone without getting big. 23:09 Speaker 1: You know what I mean? Like, just for the other effects and not for the physical effects. I wish I could do more. But unfortunately, 23:15 Speaker 1: yes, it comes along with 23:18 Speaker 1: adding 20 pounds of muscle that I don't want. 23:21 Speaker 0: True that, man. Each his own, right? Yeah. 23:24 Speaker 0: Alright, man. Let's dig into oxytocin. 23:27 Speaker 0: So it's the love drug. What's the love drug all about, bro? Who should take it and why? So 23:33 Speaker 1: we all have I guess here's the general thing, like, we all have well, maybe have heard of oxytocin. 23:39 Speaker 1: K, the love drug. Right? It is what 23:42 Speaker 1: women get filled with post sex, 23:46 Speaker 1: and it's what men get filled with during sex. Right? Those of you men who know who's who've had sex, my guess is that post sex, you're really not feeling super duper cuddly because 23:56 Speaker 1: then it's flooded out of you, but women are. 23:59 Speaker 1: So they get flooded with oxytocin. 24:02 Speaker 1: Well, pre and 24:03 Speaker 1: post sex, also like a woman when they just have a baby, right, they are flooded with oxytocin. 24:09 Speaker 1: So they just feel this overwhelming, like, 24:12 Speaker 1: love and want to 24:14 Speaker 1: touch and cuddle the baby. Right? And that's a survival mechanism for our children in the ancient times. Right? We want that woman 24:21 Speaker 1: to love that baby because the baby is defenseless and weak. 24:25 Speaker 1: We need the woman to hold it tight and keep it close to her at all times or else 24:31 Speaker 1: something's gonna kill it. This is like we're talking about caveman times. This is why biology 24:36 Speaker 1: we kind of evolved this way. So 24:39 Speaker 1: it helped. This is like God's way of making sure that our species survives. 24:44 Speaker 1: Good way to put it. And 24:47 Speaker 1: so, yeah, it's gonna give you overwhelming feelings of 24:50 Speaker 1: maybe not overwhelming. It depends how much you actually do. But that's what it does normally in the body. It also, 24:55 Speaker 1: I guess, clinically nowadays, the most common use for oxytocin is 25:01 Speaker 1: to induce labor 25:03 Speaker 1: with women 25:04 Speaker 1: and to help women lactate. 25:07 Speaker 1: I So, doc, that's what it is, like, FDA approved for. 25:14 Speaker 1: And, 25:15 Speaker 1: yeah, that's a common application today. Now 25:19 Speaker 1: it can be done 25:21 Speaker 1: and used for a bunch of different reasons 25:23 Speaker 1: that are kind of cool nowadays. 25:25 Speaker 1: It'll help men. I mean, and you can help me kind of rattle off some different things that this does. But 25:30 Speaker 1: it will help both men and women the feeling during sex, right, the actual sensitivity 25:35 Speaker 1: and the orgasm 25:39 Speaker 1: ease and intensity. 25:41 Speaker 1: Guess if you're a man and you have 25:44 Speaker 1: early 25:46 Speaker 1: too fast problems, you probably don't wanna take this. 25:49 Speaker 0: Makes you really sensitive. Yeah. So don't take it with PT-one hundred 41. 25:54 Speaker 1: Or do. 25:56 Speaker 0: Double enhanced. If 25:58 Speaker 0: you wanted extra good. My wife in general, bro, when I give her that stuff, she is sensitive, bro. So I give her this too. It'll be a doozy. 26:06 Speaker 0: It's kind of interesting though, you're talking about 26:10 Speaker 0: helps them lactate. You know, 1 thing that 26:13 Speaker 0: blew my mind, I don't know, 26:15 Speaker 0: you know, women are women and, you know, I'm not 1. So, 26:18 Speaker 0: 1 thing that I was super surprised by, 26:21 Speaker 0: well, not the surprise of a lot of women don't lactate well, that, okay, that's cool. I didn't know that, but there you go. 26:27 Speaker 0: And so they need to feed their babies. So women 26:31 Speaker 0: basically swap milk. It's a common I thought it was disgusting. I don't know, whatever. Was like, what? Because my That's why women sell milk on Craigslist. I didn't know that. So my wife, you know, I think when you had Jack's, I think some of her friends weren't lactating. 26:46 Speaker 0: They would, would, she would give them milk and I was like, That is gnarly. Like, Woah. She's like, It's totally common. And like, I was like, Wow, just wow, I was blown away by that. So 26:55 Speaker 0: interesting. So this will help if you're 1 of those ladies that come, you know, have that problem, this will help. 27:00 Speaker 0: It's common is the whole point of all that is it's more common than you when you know because it was multiple women that she would give her breast milk to. I think women know that, but us men don't. 27:08 Speaker 0: Yeah, had no clue. I thought it was gross, but whatever. I guess I'm wrong. Hey, 27:13 Speaker 1: man, when I had like an eye infection, I put breast milk in my eye. I- That's brings to my wife. She told you and it fixed it. Right? You're like, where's the breast milk in it? It did. I was like, oh, but okay. 27:25 Speaker 1: Need to fix it. Yeah. 27:28 Speaker 0: We were discussing this the other day, how ironically, where, you know, like my wife in general, we've chosen to breastfeed our boys for a very long time. And 27:36 Speaker 0: 3 1 of the reason being is that stuff we feel is of superpower, 27:40 Speaker 0: and Will and I are literally just discussing this. And my son, Jax, is he's 27:44 Speaker 0: off the chart smart. So I can't say for sure that it's the breast milk, but he was breastfed for a long time, and I definitely think it's a big part of it. 27:52 Speaker 1: I think so. I think that, you know, we always it's general it's in society like, Oh, man, 27:58 Speaker 1: get your kids to stop breastfeeding as soon as possible. That's embarrassing, right? Your kids this- Our doctor would like, Dude, as long as you can. But apparently, 28:07 Speaker 1: like, I mean, that stuff is, yes, is like an elixir of the gods. It makes so 28:12 Speaker 1: a kid that is breastfed longer is gonna be healthier, 28:15 Speaker 1: stronger. 28:17 Speaker 0: So we read, so we did it because of that. Yeah. So, mean, each his own, but I mean, poor ladies, my wife, man, has been breastfeeding now because then we had Mason right after and she just went from kid to kid, poor girl, but she 28:31 Speaker 0: was built for it, man. She was built to be a mom. Don't think every woman's, not every woman is so freely, 28:36 Speaker 0: you know, like my wife, but 28:39 Speaker 0: it helps, man. We're living proof. My son seemed pretty, pretty bright. Yep, yep, yep. There you go. 28:46 Speaker 0: Emotional So bonding, trusting intimacy, 28:49 Speaker 0: that's kind of cool. I mean, I know Will has tapped on that, but it 28:52 Speaker 0: helps to bring that bond with men and women. 28:56 Speaker 0: That's kind of cool. Know, men, I don't know, at least me. We were talking about this off screen too. 29:02 Speaker 0: Don't know, I don't like talking about emotions and all that stuff, my poor wife. I don't 29:06 Speaker 0: like to talk about all that stuff, you know? So this stuff kind of helps with that stuff, apparently. I haven't tried it, so maybe I need to try it. We have like a sensual talk. Yeah. Let's talk about emotions today. Yes. 29:17 Speaker 1: They have quoted in this 29:22 Speaker 1: We were reading a study earlier and it said, like the direct line was, Gives you a warm, peaceful, 29:30 Speaker 1: content state. 29:32 Speaker 0: Yeah, which is cool. Yeah. Well, it brings down cortisol, and we wouldn't even brought that up, which is a huge 1 because, 29:39 Speaker 0: like 29:41 Speaker 0: we were saying earlier, 29:44 Speaker 0: when you're ready to, like, fight or flight, like, it's because you had to fight something off like a bear. There's no bears anymore, 29:50 Speaker 0: but there is a bear. It's sitting in traffic. I don't know if you're like me. When I'm in traffic, I'm pissed. I hate it. I hate sitting in traffic. We live in Orange County, so it's part of the game, but 30:01 Speaker 0: this helps with that, man. It brings down cortisol to stress. So pretty darn cool. Yeah, if you could, I mean, which is huge, right? If this 30:10 Speaker 1: really, really effectively 30:12 Speaker 1: reduces and brings down cortisol, you can extrapolate 30:15 Speaker 1: that Essentially, if our cortisol hormone is going off, right, that's 30:21 Speaker 1: our fight or flight reaction, okay? 30:24 Speaker 1: When we are in that state, 30:26 Speaker 1: the last thing if we're talking about fitness, right, the last thing our body is doing is burning fat or building muscle, okay? 30:33 Speaker 1: Again, like you said, if that's going off, our body is programmed to be in ancient times, right, our body is actively literally just disintegrating our muscle, turning 30:43 Speaker 1: it into sugar and filling our blood with sugar to give us fast energy right now. It does not care about the future. It just wants us to get through this situation we're dealing with And right that would be like fighting a bear off in a cave with no food and it's freezing. 30:59 Speaker 1: So 31:01 Speaker 1: that sucks. So if we can and this is the same reason that we build muscle primarily. Really, all your muscle is built at night while you're sleeping. Why? Because we're not stressed out. Right? Our cortisol is that hormone is not going off, and our body can finally, 31:16 Speaker 1: Okay, I don't got to deal with these exterior stressors and deal with that. I can now just go back to kind of base mode, which is rebuilding everything, 31:25 Speaker 1: putting long short term memory 31:27 Speaker 1: into long term memory, 31:28 Speaker 1: building up actual muscle. 31:31 Speaker 1: You believe it or not, like, if you have a good night's sleep, you'll burn a lot of fat. Yeah. You will wake up later because your body is getting rid of all this excess bad stuff. This is getting rid of It doesn't need those fat stores anymore if you are relaxed. 31:47 Speaker 0: I don't even think we talk about that enough. I mean, I'll give you a quick little story just about me recently where I've actually talked about it quite a bit. I don't sleep well. I don't know, man. Like I said, I have a 4 year old and an 18 old. They're often in my bed and it's just is what it is. It's part of the game, right? So I'm getting kicked in the head, blah, blah, blah, and I don't sleep well. So anyways, I recently had my blood work from a good buddy of mine, and we're going through my blood work and blah, blah, And we're talking about, I've just been really tired, and like, take enough, I'm healthy, I eat right, blah, blah, blah. I shouldn't be as tired. And he said, 32:19 Speaker 0: Well, how are you sleeping? As doctors should. 32:22 Speaker 0: This is how doctors should talk. They should dig into things. Right? And I said, I'm 32:28 Speaker 0: not sleeping well. I haven't slept well for a long time, but I've just become used to it. So he and I were talking about this sleep, blah, blah, blah. 32:36 Speaker 0: A few days later, my wife and I got a babysitter for the 1st time since my 2nd son was born. We got a hotel. We got a ton of sleep. The next day, the boys were so tired, so they fell asleep really early, so I had 2 32:47 Speaker 0: rad nights of sleep. Here's the point. 32:50 Speaker 0: The next 2 days, I was firing on all cylinders. 32:55 Speaker 0: I was focused. 32:56 Speaker 0: I felt great at work. 32:58 Speaker 0: The point of that is sleep, man. I don't think we talk about it enough. If you're not sleeping well, man, like Will said, your body repairs, 33:04 Speaker 0: it's a big, big deal. And I know that, but I had not thought of it in a long time. My buddy kind of shined the line of it, and it's, man, sleep is huge. It's huge. It's huge. You ask any, like, pro bodybuilder where that's their job or 33:18 Speaker 1: athlete, right? I mean, when I was playing college football, like, our strength coach would be like, Now go get some sleep. Do not stay out partying all night long. Right. 33:25 Speaker 1: Get some damn sleep so your muscles can recover. 33:29 Speaker 1: Huge mess. It's 33:31 Speaker 1: so true. 33:32 Speaker 1: So, yeah, there you go. It will 33:36 Speaker 1: help stimulate and help 33:38 Speaker 1: balance out talking about hormones again, right? Really help balance women's 33:43 Speaker 1: hormones, 33:44 Speaker 1: help kind of get your menstrual cycle in check 33:49 Speaker 1: if it isn't in check. 33:52 Speaker 1: Increased orgasm, 33:53 Speaker 1: feeling of sensitivity, and just 33:56 Speaker 1: mutual 33:57 Speaker 1: feelings of closeness and bonding. 33:59 Speaker 1: They've 34:00 Speaker 1: done studies on 34:02 Speaker 1: PTSD. 34:04 Speaker 1: So given it to PTSD patients, a lot of studies say, know, some of the worst PTSD symptoms or 34:10 Speaker 1: subjects 34:11 Speaker 1: saw the most increase or decrease of their PTSD, which 34:16 Speaker 0: kind of seems Makes sense because it lowers the cortisol, so it totally makes sense. Brings calm calms calms nerves. They ran a study in 34:25 Speaker 1: addiction scenario 34:26 Speaker 1: and gave out, like, chronic alcoholics who were not 34:30 Speaker 1: who were craving alcohol when they had their worst cravings. They would give them like 40 34:36 Speaker 1: 40 34:37 Speaker 1: not milligram, 40 microgram or 40 IUs, which is like 80 micrograms 34:42 Speaker 1: dose 34:43 Speaker 1: right then and there. And the feedback on that 1 was overwhelming positive. Like, basically, everybody said, woah. It just took away my craving. Well, that's a trip, dude. Yeah. That's crazy. 34:55 Speaker 1: It's 34:57 Speaker 1: going to help you relax, 34:59 Speaker 1: take the stress off. 35:01 Speaker 0: Yeah. It kind of boosts your overall well-being, which is huge, again, with cortisol, blah, blah. But in today's world, is go, go, go, go, go, we are all caught in the rat race. 35:12 Speaker 1: This is 1 that's gonna help with that. Yeah, that was the other thing. On this fight or flight thing, guys, if you drink alcohol, alcohol is poison. Okay? So 35:22 Speaker 1: We all know, like, it doesn't burn off out of you until, like, 2PM the next day. So that entire time that we have alcohol in you, 35:30 Speaker 1: your body is now in this fight or flight stage and 35:34 Speaker 1: shooting off cortisol. Right? People are like, oh, I'm fat because I drink. Right? You're not fat. You're really not fat because 35:40 Speaker 1: of the calories that alcohol gave you. You're fat now because 35:44 Speaker 1: of your cortisol. 35:45 Speaker 1: Your your body is just never burning fat, and it is trying to store fat, right, because it's stressed and thinks you gotta fight a bear off in a cave. 35:53 Speaker 1: What did you do with me? Food. So it's trying to store all your food, plus your inhibitions on on food choices go out the window there, right, and see everybody else. I know the truth. 36:02 Speaker 1: Late night, like burgers 36:04 Speaker 1: because you're drinking. A, you make worse food decisions, but b, your body is in a constant state of just trying to store fat, 36:12 Speaker 1: burn muscle, turn it into sugar, which which inevitably gets stored as long term fat, 36:17 Speaker 1: and cycle again. 36:19 Speaker 0: That damn alcohol, man. I'll tell you a quick little story, a little side note. I think my people might find it funny. So when I 1st got sober, was did my sober living, then I moved down to with a buddy down by the beach, Newport Beach, and I'd be up early, right? So I'd be up early having my coffee, reading, you know, doing my readings. And right around 06:00, 36:37 Speaker 0: every weekend, I'd be sitting on the porch 36:40 Speaker 0: and there would always be these women holding their shoes walking down the street, you know, and they would always walk by because I lived on a street that it was a common street. And I'd always say, 36:50 Speaker 0: was it worth it? And I always got stuff like, no. No. 36:55 Speaker 0: Or can't. Yeah. Kinda funny. Don't drink alcohol, ladies. You won't be that girl. Yeah. Kinda find that funny. 37:01 Speaker 1: Yeah, no, no. Actually, that's cool. Oh, last thing is, right, 37:06 Speaker 1: it's seen in these clinical models, right, for actually labor 37:10 Speaker 1: induction 37:13 Speaker 1: in producing telling women to 37:15 Speaker 1: produce more milk. 37:17 Speaker 1: They are doing, like, IV injections or intramuscular injections. 37:21 Speaker 1: But for 37:22 Speaker 1: the common recreational 37:25 Speaker 1: use, 37:26 Speaker 1: my suggestion would be, like SubQ works, but I think nasal spray is gonna be the best route of administration. 37:33 Speaker 0: Yeah. That's That's 37:35 Speaker 1: where a lot of the tests and research has been done on 37:39 Speaker 1: general kind of mood happiness, 37:42 Speaker 1: brain, anti brain fog, 37:44 Speaker 1: and, yes, feeling social. 37:47 Speaker 1: I forget the word, but basically, like, just everybody, if you're well good in social settings, 37:52 Speaker 1: which we all know some people I haven't been, and 37:56 Speaker 1: it really helps do that. You'll start to like people a little bit more. 38:01 Speaker 0: Yeah, it seems like, I know this isn't nootropic, but, you know, we have talked about this numerous times where it seems like the nootropics 38:08 Speaker 0: can best be done nasal spray. I mean, it makes sense because it's going right into your brain, but logic's 38:16 Speaker 0: there. 38:18 Speaker 0: You know what mean? 38:21 Speaker 1: And I would say dosing on that guy is between, like, 38:26 Speaker 1: what should I equate it to? About 40 38:30 Speaker 1: to 60 micrograms 38:32 Speaker 1: a day, 38:34 Speaker 1: okay, for oxytocin. 38:37 Speaker 1: That's my answer that I'm sticking with it. 38:41 Speaker 1: But 38:42 Speaker 1: it's all a research project. You know what I'm saying? Like, we all 38:45 Speaker 1: need to try and try different things. 38:48 Speaker 1: Men, if you've taken 38:50 Speaker 1: way too much of this stuff, you might find yourself wanting to hold hands with each other, and that's probably time to lower the dose. 38:57 Speaker 0: He's 38:58 Speaker 0: so sensitive. 39:00 Speaker 0: He's taking too much oxytocin. 39:04 Speaker 0: Ladies, if you get a man that doesn't open up and want to talk about feelings, 39:09 Speaker 0: maybe give him some oxytocin. 39:10 Speaker 1: My wife's probably listening to this. She's gonna- She's like, Oh, I'm gonna spike his drink 39:15 Speaker 1: with that. Yeah. 39:17 Speaker 0: I married the right woman, man. I told her long ago, like, I don't wanna talk about all my feelings and emotions. She's like, Okay. She's a good 1. Good about stuff. Yeah. Talk to your friends. Yeah. That's what they're there for. They like it. It's just gonna stress us out and, like, make us unhappy and everybody unhappy. 39:33 Speaker 0: Didn't do that, man. 39:35 Speaker 0: Each his own. 39:37 Speaker 1: That was a good 1, man. These are interesting. These are good ones. I'm glad we dug into this 1. And more honestly, like on these ones, right, just like most peptides, there's just a ton of R and D going on and 39:48 Speaker 1: more will be revealed. 39:50 Speaker 1: Yeah. Hell yeah. And the downside is nothing really. Not much at all. 39:56 Speaker 0: Yeah. 39:57 Speaker 0: I mean, as we go and go, we learn more and we learn more and we learn more. We have never even pretended that we know at all. Just try to study it and try our best to kind of articulate 40:06 Speaker 0: the stuff that we know, but we definitely are constantly learning ourselves, 40:11 Speaker 0: constantly. 40:12 Speaker 0: Some things that we even thought months ago, we're like, oh, that's actually, we need to do it a little bit different. 40:17 Speaker 0: All should be seeking that stuff. 40:20 Speaker 1: True. Trial 40:22 Speaker 0: and error is huge. I mean, we've talked about it, Will and I, to take kind of, you know, go out in left field for a 2nd where people have discussed quite a bit in regards to the dosing of like GLP-1s, 40:34 Speaker 0: blah, blah, blah. 40:35 Speaker 0: I mean, if it reads on paper, 40:38 Speaker 0: that's awesome. But like, you know, we have worked with lots of many, many, many, many, many friends with hands on in here, and we can say that's the paper's wrong. Like in our experience, 40:49 Speaker 0: we have found different. So, I mean, I don't know, that reads on paper, great. But 40:54 Speaker 0: what's better than 1st hands on, like literally seeing physically seeing the changes in people and how they dose things? There's nothing better than firsthand knowledge, man. Nope. So that's how you're gonna learn yourself. Like, try it. Yep. So 41:09 Speaker 0: good stuff, man. That was a good 1. So next 1 will be the Q and A. I will be putting out the links today and tomorrow, and we will be recording on 41:17 Speaker 0: Friday for the Q and A. But anything else before we go? This, 41:21 Speaker 1: we did this based on someone's request. 41:25 Speaker 1: I remember that was. That was a good idea. We're open to request. You know, 1 other thing, 1 thing that we were gonna do was, and somebody else requested this, was 41:33 Speaker 1: they were interested in what type of, like, over the counter supplements that we 41:37 Speaker 1: take, 41:38 Speaker 1: that we like, 41:39 Speaker 1: had experience with, kind of like BCAAs, 41:42 Speaker 1: creatine, protein. 41:44 Speaker 1: So we might 41:45 Speaker 1: do that 1. 41:47 Speaker 0: Yeah, if that's something of interest, start blowing up our DMs and like, if that's something that more people are interested in, you know, different types of creatine. We've talked about monohydrate and HCL, blah blah blah. So stuff like that. If that's of interest, let us know. We're listening. Sure. We're gonna break down the 3 42:02 Speaker 1: different types of whey protein and how they're made in like 42:05 Speaker 1: absorption times. I don't know that. That's an interesting subject. And 42:12 Speaker 1: yeah, so we're open to requests. 42:15 Speaker 0: Good stuff, man. Well, alright, guys. We will catch you on the flip side. 42:19 Speaker 3: Take care. Good night.